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Briumvi: The New MS Drug That's Shaking Things Up! Side Effects 1 Views • 3 months ago

What do you get when you mix B-cells, mouse DNA, and a drug name that sounds like a sci-fi sidekick? Say hello to Briumvi—the newest MS medication strutting onto the scene like it owns the infusion suite! In this video, we break down what makes Briumvi different from the OGs like Ocrevus and Rituximab, how it works (spoiler: it’s a B-cell bouncer), and why your phlebotomist might start sending you birthday cards. If you're newly diagnosed with Multiple Sclerosis or just trying to make sense of the MS treatment rollercoaster, this one's for you—with jokes, analogies, and absolutely zero co-pay assistance. Subscribe, laugh, and learn what makes this new B-cell bouncer drug worth talking about (and maybe even trying).

#MultipleSclerosis #Briumvi #LivingWithMS #NewMSDrug #MSTreatment
#MSAwareness #MSCommunity #MSWarrior #BCellTherapy #LifeWithMS

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Please leave a comment of anything you may have questions about when it comes to Multiple Sclerosis.

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Chapters

00:00:00 The New Kid on the MS Block
00:00:35 B-Cells, CD20, and Why Mice Are Involved (Briefly)
00:01:13 Ocrevus, Rituximab, and the Case of the Familiar Face
00:01:46 Wait, Before We Go On… (Like, Subscribe, All That Jazz)
00:02:07 One and Done (Hopefully)
00:02:34 Relapses, MRIs, and Disability, Oh My!
00:03:04 From the Mildly Annoying to the "Call Your Doctor Immediately"
00:03:43 Pricey, “Me Too,” and Maybe a Good Thing?
00:04:20 Babies, Bloodwork, and Other Fun Stuff Briumvi Doesn’t Like
00:04:47 So, Is Briumvi the Hero MS Deserves? Or Just a Flashy New Sidekick?

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Please remember that the I'm Not Myelin channel is dedicated to providing informative and educational content about helping those with Multiple Sclerosis. But be advised that our videos do not provide medical advice and should not be used as a substitute for professional medical consultation, diagnosis, or treatment. Always seek guidance from a qualified healthcare provider regarding any medical concerns, and never delay or disregard professional advice based on our content. Stay informed, stay curious, and thank you for watching!

Impact of NIACIN (Vitamin B3) on Cholesterol Side Effects 1 Views • 3 months ago

NIACIN (Vitamin B3) Impact on Cholesterol
https://us.fullscript.com/plan....s/drjinsung-dr-jin-s

Nicotinic Acid(Niacin) and Nicotinamide or Niacinamide (amine group attached).
(Flushing)😡😡 (non-Flushing)

Deficiency associated with the following.
Highly refined diets-corn, refined carbs, sugars, rice and alcohol, vegan diet.
GI disease
Antacids
Certain medications
Excess alcohol use

Pellegra-4 Ds
Dermatitis
Dementia
Diarrhea
Death

Impact on cholesterol
Decreases LDL, triglycerides, Lipoprotein (a) Lpa and increase HDL.

Foods: Liver, chicken breast, tuna, salmon, turkey, anchovies, and eggs, nutritional yeast
Partially synthesized in the liver from tryptophan requires riboflavin(B2)/iron

Test:
Measured in urine-niacin metabolites.

Other benefits:
1. Brain health
2. Cholesterol levels
3. Skin health-UV protection and reactions
4. Pellagra-mental confusion, diarrhea, weakness, loss of appetite, scaly skin especially in sun exposed areas. (dermatitis, dementia and diarrhea)
5. ATP production
6. Cell signaling and making and repairing DNA/antioxidant.
7. Diabetes-insulin sensitivity.
8. Memory-brain and nerve health
9. Arthritis-reduces inflammation
10. Sleep-manages stress levels
11. Hair growth-oxygen
12. Chapped lips.
13. Nutrient metabolism-proteins, fats and carbohydrates

Dosage: 1200 to 2000 mg per day.
Side effects: Flushing(aspirin or applesauce), itchy skin, increase uric acid and on rare occasions hepatotoxicity

HPS2 Thrive-use laropiprant to get rid of the flush
AIM High-Niacin plus a statin

HPS2 Thrive https://www.nejm.org/doi/full/....10.1056/nejmoa130095
AIM High https://www.nejm.org/doi/full/....10.1056/nejmoa110757

Dr. Jin Sung is a Chiropractic Physician who specializes in the management of complex chronic conditions in Massachusetts, 30 minutes north of Boston. He utilizes natural and alternative therapies to help manage complex cases such as Hashimoto's, autoimmune conditions, IBS, SIBO, chronic fatigue, brain fog, early Alzheimer's, etc.

www.DrJinSung.com
https://www.facebook.com/DrJinWSung/

Office Contact
978 688-6999
www.drjinsung.com

SEARCH on Dr. Sung's Online Store-https://us.fullscript.com/welcome/drjinsung
Metagenics Niatin
Nicotinic Acid

Dr. Sung's Online Supplement Dispensary-conditions apply. Certain companies will require a prescription from Dr. Sung.

The content of this video is for educational purposes only and does not constitute medical advise. Please consult with your physician before embarking on any dietary changes or taking any nutritional supplements.

Microbiology Q&A CLINICAL ANTIBIOTICS Meropenem Vaborbactam Side Effects 1 Views • 3 months ago

Meropenem+vaborbactam
Meropenem+vaborbactam is a powerful antibiotic combining meropenem, a carbapenem, with vaborbactam, a novel non-β-lactam β-lactamase inhibitor. It is used to treat infections caused by certain strains of carbapenem-resistant Enterobacterales, Acinetobacter baumannii and Pseudomonas aeruginosa [2]. Vaborbactam protects meropenem from degradation by targeting and inactivating certain serine β-lactamases (Ambler class B).
This medication is considered a Reserve antibiotic, meaning it is reserved for specific situations as a last resort due to the risk of emerging resistance. The World Health Organization (WHO) recommends reserving this antibiotic for targeted treatment of severe infections caused by laboratory-confirmed Klebsiella pneumoniae carbapenemase-producing Enterobacterales. It could also be considered for severe complicated urinary tract infections, intra-abdominal infections, and hospital-acquired pneumonia when other options are unsuitable. Empiric use, where the specific pathogen is unknown, is only recommended in very select cases of seriously ill patients, such as those with sepsis or septic shock, where a multidrug-resistant pathogen is suspected.
Meropenem+vaborbactam exhibits activity against a wide range of bacteria, including Gram-positive aerobic bacteria, Gram-negative aerobic bacteria, and anaerobic bacteria. Importantly, vaborbactam boosts meropenem's effectiveness against many multidrug-resistant Gram-negative bacteria by inhibiting ESBLs, AmpC beta-lactamases, and Klebsiella pneumoniae carbapenemases. However, it is crucial to understand that it is not effective against bacteria producing metallo-beta-lactamases (NDM, VIM, IMP) or Ambler class D carbapenemases like OXA-48.
The standard adult dosage is 4g (2g meropenem + 2g vaborbactam) administered intravenously every 8 hours. Importantly, this medication is currently not licensed for use in children or neonates.
While generally well-tolerated, with side effects similar to meropenem alone, meropenem+vaborbactam is notably less harmful to the kidneys compared to other antibiotics used for similar infections.
This information is sourced from the AWaRe antibiotics book by the World Health Organization. For further details, please refer to: https://iris.who.int/bitstream..../handle/10665/365135
#AntibioticResistance #AntimicrobialResistance #Superbugs #WHO #AWaRe #MeropenemVaborbactam #ReserveAntibiotics #InfectiousDiseases #Healthcare #GlobalHealth #Sepsis #HospitalAcquiredPneumonia #UrinaryTractInfection #IntraAbdominalInfection #KlebsiellaPneumoniae
Disclaimer: This video is for informational purposes only and does not constitute medical advice. Always consult a healthcare professional for diagnosis and treatment.

What Are The Side Effects Of Midazolam Interactions? - First Response Medicine Side Effects 1 Views • 3 months ago

What Are The Side Effects Of Midazolam Interactions? In this informative video, we focus on the side effects and interactions of midazolam, a medication commonly used in emergency and critical care medicine. Understanding how midazolam interacts with other substances is essential for anyone involved in patient care, especially first responders. We will discuss the potential risks associated with combining midazolam with central nervous system depressants, which can lead to serious complications such as respiratory depression and hypotension.

We will also cover the signs of overdose, allergic reactions, and the importance of monitoring vital signs in patients who have received midazolam. First responders play a vital role in identifying these symptoms quickly and providing necessary interventions to ensure patient safety. Additionally, we will touch on the use of flumazenil, the antidote for midazolam toxicity, and the precautions that must be taken when administering it.

Join us for a detailed discussion about midazolam interactions and side effects, and subscribe to our channel for more essential information on first responders medicine.

⬇️ Subscribe to our channel for more valuable insights.

🔗Subscribe: https://www.youtube.com/@First....ResponseMedicine/?su

#Midazolam #EmergencyMedicine #CriticalCare #FirstResponders #PatientSafety #RespiratoryDepression #Hypotension #Overdose #AllergicReactions #Sedation #CNSDepressants #Flumazenil #PatientCare #MedicalInterventions #EmergencyResponse

About Us: First Response Medicine is your essential resource for all things related to emergency and critical care. Our channel is dedicated to providing clear and practical information on emergency medicine, covering topics such as trauma management, life-saving procedures, and the latest in critical care practices.
Please note that all content is for informational purposes only and should not be considered medical advice. Always conduct your own research and consult with professionals when necessary. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

6 Estradiol Side Effects & How You Can Heal Side Effects 1 Views • 3 months ago

Anytime you take exogenous hormones – meaning not what your body naturally makes, but hormones you take – you may experience some side effects. And that’s true of all hormones.

Learn more: https://genesisgold.com/hypoth....alamus/estradiol-sid

Even your own endogenous estradiol, that which your body naturally makes, can cause side effects. Especially if it’s out of balance with your progesterone. Remember estrogen is the fertilizer growing lush healthy tissue. Progesterone is the gardener – turning off estrogens growth unwanted promoting effects – like tumors.

00:00 Estradiol Side Effects and How to Deal

Side Effects Include ::

00:35 Melasma
01:08 Water retention
01:31 Breast pain and swelling
01:58 Increased uterine bleeding
02:21 Anxiety
02:31 Blood clots

Estrogen side effects are something we talk about a lot in my Hormone Support Group, which is FREE to join by the way when you sign up for my free Hormone Reboot Training.

If you have a family history of blood clots and especially if you’ve ever had a blood clot, then you are not a candidate for oral estrogen therapy especially in birth control. Talk to your health care provider to see if you might use estrogen transdermally or intravaginally.

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This video is not designed to and does not provide medical advice, professional diagnosis, opinion, treatment or services to you or to any other individual. Through my videos, blog posts, website information, I give suggestions for you and your doctor to research and provide general information for educational purposes only.

The information provided in this video or site, or through linkages to other sites, is not a substitute for medical or professional care, and you should not use the information in place of a visit, call consultation or the advice of your physician or other healthcare provider. Genesis Health Products and Deborah Maragopoulos FNP are not liable or responsible for any advice, course of treatment, diagnosis or any other information, services or product you obtain through this video or site.

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