New research indicates that high-dose thiamine (vitamin B1) holds promise in combating cancer by specifically targeting and disrupting the altered metabolism characteristic of tumor cells. This approach, particularly effective in pancreatic cancer and neuroblastoma, aims to restore normal metabolic pathways within cancer cells, leading to their programmed death. Unlike conventional chemotherapy, this strategy appears to achieve its effect without the severe side effects often associated with harsh drug treatments, offering a potentially gentler yet effective therapeutic avenue. The mechanism involves leveraging thiamine's role as a coenzyme in vital metabolic processes, where high doses can essentially "overload" cancer cells' unique metabolic needs, triggering apoptosis (cell death) and slowing their growth.

The most profitable drug for many years running, Humira counters the effects of a chemical known as TNF and in doing so dramatically improves moderate to severe plaque stage psoriasis. Maintenance requires twice monthly self-administered injections just under the skin akin to insulin therapy. Effectiveness may decrease over time. Since it suppresses the immune system, it may lead to spread of serious infections such as hepatitis, staphylococcus and TB. A small increase in cancers may occur.
The drug costs about $50,000 each year.

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Montelukast, sold under the brand name Singulair, is a widely prescribed medication for asthma, seasonal allergies, and exercise-induced breathing problems. In this quick guide, learn how Montelukast works, its major uses, correct dosage, and key side effects — all in under 2 minutes.

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Lipid-lowering medications, also known as lipid-lowering drugs or hypolipidemic agents, are a class of medications used to manage and lower elevated levels of lipids (fats) in the blood. These medications are primarily prescribed to reduce the risk of cardiovascular diseases, including heart attacks and strokes, which are often associated with high levels of cholesterol and other lipids in the bloodstream.

The main types of lipids that are targeted by these medications include:

1. Cholesterol: Cholesterol is a type of lipid that is essential for various bodily functions but can be harmful when present in excessive amounts. There are two main types of cholesterol: low-density lipoprotein (LDL) cholesterol (often referred to as "bad" cholesterol) and high-density lipoprotein (HDL) cholesterol (often referred to as "good" cholesterol).

2. Triglycerides: Triglycerides are another type of lipid that is stored in fat cells and released for energy when needed. High levels of triglycerides are also associated with an increased risk of cardiovascular diseases.

Lipid-lowering medications work through different mechanisms to lower cholesterol and triglyceride levels in the blood. Some of the common classes of lipid-lowering medications include:

1. Statins: Statins are one of the most widely prescribed classes of lipid-lowering medications. They work by inhibiting an enzyme in the liver that is responsible for producing cholesterol. By reducing cholesterol production, statins effectively lower LDL cholesterol levels. Examples of statin medications include atorvastatin, simvastatin, and rosuvastatin.

2. Bile Acid Sequestrants: These medications work by binding to bile acids in the intestines, which are involved in the digestion and absorption of fats. This binding prevents the reabsorption of bile acids, leading the liver to use more cholesterol to produce new bile acids, thus reducing LDL cholesterol levels. Cholestyramine and colesevelam are examples of bile acid sequestrants.

3. Ezetimibe: This medication works by inhibiting the absorption of cholesterol from the intestines. It can be used alone or in combination with other lipid-lowering drugs, such as statins.

4. Fibrates: Fibrates primarily target triglyceride levels and increase HDL cholesterol levels. They work by activating a receptor that regulates lipid metabolism in the liver and muscle cells. Fenofibrate and gemfibrozil are common fibrates.

5. PCSK9 Inhibitors: Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors are a newer class of medications that target the degradation of LDL receptors. By inhibiting PCSK9, these drugs increase the number of LDL receptors on the surface of liver cells, leading to increased removal of LDL cholesterol from the bloodstream. Evolocumab and alirocumab are examples of PCSK9 inhibitors.

6. Omega-3 Fatty Acids: Omega-3 fatty acid supplements, often derived from fish oil, can help lower triglyceride levels. They are usually recommended for individuals with high triglyceride levels.

It's important to note that lipid-lowering medications are often prescribed alongside lifestyle changes, such as a heart-healthy diet, regular exercise, and smoking cessation, to effectively manage lipid levels and reduce the risk of cardiovascular diseases. The choice of medication depends on an individual's lipid profile, medical history, and overall health status, and should be determined by a healthcare professional. Regular monitoring and follow-up are essential when taking these medications to ensure their effectiveness and address any potential side effects.

Fenofibrate is a medication that is used to lower cholesterol and triglyceride levels in the blood. It is a member of the fibrate class of drugs and has been used for several decades to treat these conditions. In this video, we will explore the benefits and side effects of Fenofibrate, so that you can make an informed decision about whether it is the right choice for you.
Chapters (Powered by ChapterMe) -
00:00 - Benefits and Side Effects of Fennifibrate
03:29 - Side effects of Fennifibrate
04:41 - Cholesterol and triglyceride lowering strategies and tips
06:09 - Lowering cholesterol levels through healthy eating, physical activity, and quitting smoking
08:25 - Lifestyle and medication options for lowering cholesterol
10:03 - Fennifibrate safety guidelines

What is Fenofibrate?.
Fenofibrate is a medication that is used to lower cholesterol and triglyceride levels in the blood. It works by activating the peroxisome proliferator-activated receptor alpha (PPARα), which helps to decrease the production of triglycerides and increase the production of high-density lipoprotein (HDL) cholesterol. This medication is available in different forms, such as capsules and tablets, and is usually taken once a day with food.
Fenofibrate is a prescription medication and should only be taken under the supervision of a healthcare professional. It is important to follow the dosage instructions provided by your doctor and to let them know if you experience any side effects.
Benefits of Fenofibrate.
Fenofibrate has been shown to be effective in lowering cholesterol and triglyceride levels in the blood. This can help to reduce the risk of cardiovascular disease, such as heart attacks and strokes. In addition, Fenofibrate has been shown to have other benefits, such as improving insulin resistance and reducing inflammation in the body.
One study found that Fenofibrate was able to reduce the risk of cardiovascular events by 19% in people with type 2 diabetes who had high levels of triglycerides and low levels of HDL cholesterol. Another study found that Fenofibrate was able to reduce the risk of cardiovascular events by 31% in people with metabolic syndrome.
While Fenofibrate has been shown to have benefits, it is important to note that it may not be effective for everyone. Your doctor can help you determine if Fenofibrate is the right choice for you based on your medical history and current health status.
Side effects of Fenofibrate.
Like any medication, Fenofibrate comes with its own set of side effects. Some of the most common side effects include abdominal pain, diarrhea, nausea, and vomiting. In addition, Fenofibrate can cause liver problems, such as hepatitis and jaundice. It is important to let your doctor know if you experience any of these side effects, as they may need to adjust your dosage or switch you to a different medication.
In rare cases, Fenofibrate can cause muscle problems, such as myopathy and rhabdomyolysis. These conditions can be serious and can lead to kidney damage or other complications. If you experience muscle pain, weakness, or tenderness while taking Fenofibrate, you should contact your doctor right away.
Who should take Fenofibrate?.
Fenofibrate is typically prescribed to people who have high levels of cholesterol and triglycerides in their blood. These conditions can increase the risk of cardiovascular disease, such as heart attacks and strokes. Your doctor may also prescribe Fenofibrate if you have metabolic syndrome or type 2 diabetes.
It is important to note that Fenofibrate may not be appropriate for everyone. Your doctor can help you determine if Fenofibrate is the right choice for you based on your medical history and current health status.
How to take Fenofibrate safely.
To take Fenofibrate safely, it is important to follow the dosage instructions provided by your doctor. Fenofibrate is usually taken once a day with food. It is important to take the medication at the same time each day to maintain a consistent level of the drug in your body.

"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.

Loratadine Effectiveness: Enhancing Wellness with This Medication

Loratadine is a commonly used antihistamine medication known for its effectiveness in treating allergies and related symptoms. In this video, we provide a detailed exploration of Loratadine, including its uses, benefits, and potential side effects. Join us as we delve into the medication insights, benefits for health improvement, and essential information on navigating side effects for a safe and informed usage of Loratadine.

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CINCINNATI (WKRC) - Side effects of cancer treatment can occur years later but a newer way to treat it from the inside out is showing great success.

The team at Mercy Health Fairfield Hospital says it can be life changing.

"I had to go to radiation for 50 days and five of those treatments were internal radiation," said Katheryn Sivrais.

Sivrais had radiation after a diagnosis of both breast and cervical cancer. "They tell you ahead of time, it is killing the cancer cells, but it is also going to damage good tissue."

Her surgeon Dr. James Fitzpatrick said, "She was cured of the cervical cancer, but the collateral damage was to the bladder which was right next to the cervix."

Katheryn turned to hyperbaric oxygen therapy. "It's 100 percent oxygen at a higher atmospheric pressure."

The treatment has been around for a number of years and used in general wound healing, usually for those with diabetes. But in this case, Sivrais been able to heal wounds inside her body. Hyperbaric oxygen therapy appears to reverse what's called vascular compromise that can result from radiation treatment. It is delivered two hours a day, five days a week.

"Patients will typically see improvement after 12 to 15 treatments, but we find that there's a higher success rate when they go to 40 treatments or more," said Dr. Fitzpatrick.

During treatment time patients can watch TV or movies, or take a snooze. When therapy is finished, studies show at least six out of ten have results similar to Sivrais, no more pain and complete tissue and organ healing.

There's not really a downside to this therapy but no one therapy works for everyone.

In most cases, it is covered by medical insurance plans.

There are several hospitals and health systems now in our area which offer this kind of therapy.

Singulair may trigger a journey of confusion, concern, and turmoil. For others, it ends in death. Suicidal thoughts and actions are one of the known side effects families say they didn't find out about until after their loved ones killed themselves.