Dangerous Side Effects

How to Combat 3 Common Side Effects of Tamoxifen
How to Combat 3 Common Side Effects of Tamoxifen Side Effects 4 Views • 5 months ago

Find out more about Breast Cancer Index (BCI): http://www.breastcanceranswers.....com/breastcancerind

Tamoxifen is easily the most used and recognized Hormone Therapy.

But with Tamoxifen comes with many side effects. We are sharing tips on how you can combat 3 common side effects of Tamoxifen.

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Pharmacology of Mirabegron (Myrbetriq); Mechanism of action, Pharmacokinetics, Uses, Effects
Pharmacology of Mirabegron (Myrbetriq); Mechanism of action, Pharmacokinetics, Uses, Effects Side Effects 1 Views • 5 months ago

Mirabegron is a medication primarily used to treat overactive bladder (OAB) symptoms, such as urinary urgency, frequency, and incontinence. It belongs to a class of drugs known as beta-3 adrenergic receptor agonists. Here's a detailed overview of its pharmacology:

Mechanism of Action
Mirabegron works by selectively stimulating beta-3 adrenergic receptors in the bladder. This leads to relaxation of the detrusor smooth muscle during the storage phase of the urinary bladder fill-void cycle, thereby increasing bladder capacity and reducing symptoms of OAB1.

Pharmacokinetics
Absorption: Mirabegron is rapidly absorbed after oral administration, with peak plasma concentrations reached within 3-4 hours.

Distribution: It has a volume of distribution of approximately 300 liters.

Metabolism: Mirabegron is metabolized in the liver primarily by the cytochrome P450 enzyme system, particularly CYP3A4.

Excretion: The drug and its metabolites are excreted primarily in the urine.

Half-Life: The half-life of mirabegron is about 50 hours, allowing for once-daily dosing.

Clinical Uses
Overactive Bladder (OAB): Treatment of symptoms such as urgency, frequency, and incontinence.

Neurogenic Detrusor Overactivity: Management of bladder symptoms in patients with neurological conditions.

Adverse Effects
Common: Headache, hypertension, nasopharyngitis, and urinary tract infections.

Less Common: Dizziness, constipation, and dry mouth.

Serious: Severe allergic reactions and angioedema (swelling of the deeper layers of the skin).

Drug Interactions
CYP3A4 Inhibitors: Drugs that inhibit CYP3A4 (e.g., ketoconazole, ritonavir) can increase mirabegron levels.

CYP3A4 Inducers: Drugs that induce CYP3A4 (e.g., rifampicin) can decrease mirabegron levels.

Precautions
Hypertension: Monitor blood pressure regularly, especially in patients with a history of hypertension.

Pregnancy and Breastfeeding: Use with caution and only if clearly needed.

Allergies: Inform your healthcare provider if you have any allergies to mirabegron or its components

#Mirabegron

Humira and Enbrel for Autoimmune Conditions | What's Important to Know
Humira and Enbrel for Autoimmune Conditions | What's Important to Know Side Effects 3 Views • 5 months ago

What you need to know about Humira (adalimumab) and Enbrel (etanercept) for Autoimmune Conditions.



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FDA approves over-the-counter Narcan | Here's what it means
FDA approves over-the-counter Narcan | Here's what it means Side Effects 2 Views • 5 months ago

The FDA has approved selling naloxone, or Narcan, over the counter, the first time an opioid treatment drug will be available without a prescription.

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Guaifenesin (Mucinex, Robitussin) – Side Effects, Uses, Mechanism of Action, Dosage, Warnings
Guaifenesin (Mucinex, Robitussin) – Side Effects, Uses, Mechanism of Action, Dosage, Warnings Side Effects 3 Views • 5 months ago

Guaifenesin (Mucinex, Robitussin) – Side Effects, Uses, Mechanism of Action, Dosage, Warnings
Guaifenesin, found in over-the-counter products like Mucinex and Robitussin, is an expectorant used to relieve chest congestion in conditions like colds and bronchitis. It works by increasing the volume and reducing the viscosity of secretions in the respiratory tract, aiding in mucus clearance. Common side effects include nausea, vomiting, drowsiness, dizziness, and rash. Dosages vary by age, with adults typically taking 200-400 mg every 4 hours, not exceeding 2.4 grams daily. Guaifenesin can interact with other cough medications, antihistamines, decongestants, and alcohol, which may increase the risk of side effects. Warnings include avoiding use if allergic, and consulting a healthcare provider if pregnant, breastfeeding, or having chronic respiratory conditions.
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If You Suffer from Premenstrual Dysphoria - Watch This
If You Suffer from Premenstrual Dysphoria - Watch This Side Effects 3 Views • 5 months ago

PMDD stands for premenstrual dysphoric disorder. This is not to be confused with Premenstrual Syndrome or PMS. PMS is changes in mood during certain parts of the menstrual cycle. It affects 80% of women. The mood changes can be mild to moderate. In fact, some women will just see it as feeling a little moody the week before their menstrual cycle.

PMDD is a severe form of PMS. It’s almost like turning into the werewolf when the full moon rises. For some people, it’s just that drastic. It affects 3% - 8% of women. So it’s not as common as PMS.

We treat PMDD with antidepressants or hormone therapy. I show you why some women get PMDD and why the antidepressants help. I discuss the difference between intermittent and continuous dosing with antidepressants. I also discuss the two main hormone treatments.
If you do not want to take any kind of medication, you can try lifestyle changes. The first are diet modifications such as eliminating caffeine, sugar, nicotine and alcohol and minimizing sodium. You would combine this with sleeping 7-9 hours a night and getting regular exercise – like 3-5 times a week.

Some nutritional supplements have shown to be helpful. These would be Calcium 1200mg/day, Vitamin B6 50-100mg/day. Other supplements would be Magnesium 200 – 360mg/day, Vitamin E 400 IU/day.

There are some herbal remedies that have been shown in studies to be helpful.
Agnus castus fruit extract, also known as chasteberry and Gingko biloba.


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Video on Brain Zaps from medication withdrawal
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References:
Article about how SSRI’s increase allopregnalone
Griffin LD, Mellon SH. Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. Proc Natl Acad Sci U S A. 1999;96(23):13512–13517.
Bäckström T, Bixo M, et. al. Allopregnanolone and mood disorders. Prog Neurobiol. 2014 Feb; 113:88-94. Epub 2013 Aug 23.

Schiller CE, Schmidt PJ, Rubinow DR. Allopregnanolone as a mediator of affective switching in reproductive mood disorders. Psychopharmacology (Berl). 2014;231(17):3557–3567. doi:10.1007/s00213-014-3599-x

Griffin LD, Mellon SH. Selective serotonin reuptake inhibitors directly alter activity of neurosteroidogenic enzymes. Proc Natl Acad Sci U S A. 1999;96(23):13512–13517.

Khine K, Rosenstein DL, Elin RJ, Niemela JE, Schmidt PJ, Rubinow DR. Magnesium (Mg) retention and mood effects after intravenous Mg infusion in premenstrual dysphoric disorder. Biol Psychiatry. 2006 Feb 15;59(4):327-33.

Yonkers KA, Pearlstein TB, Gotman N. A pilot study to compare fluoxetine, calcium, and placebo in the treatment of premenstrual syndrome. J Clin Psychopharmacol. 2013 Oct; 33(5):614-20.

Disclaimer: All of the information on this channel is for educational purposes and not intended to be specific/personal medical advice from me to you. Watching the videos or getting answers to comments/question, does not establish a doctor-patient relationship. If you have your own doctor, perhaps these videos can help prepare you for your discussion with your doctor.

How to use Xarelto - Explain Uses,Side Effects,Interactions
How to use Xarelto - Explain Uses,Side Effects,Interactions Side Effects 2 Views • 5 months ago

When you start taking Xarelto, make sure to read the Medication Guide provided by your pharmacist. Take this medication by mouth as directed by your doctor. For preventing strokes and blood clots due to an irregular heartbeat, take a dose once a day with the evening meal. For other conditions, such as after surgery or during a hospital stay, also take a dose once a day. For adults treating blood clots, take a dose twice a day for the first 3 weeks, then once a day. For children, the dose is usually once a day. If you are taking this medication to lower the risk of blood clots from forming again, the dose is usually taken once a day. Carefully follow your doctor's directions and do not change the dosage without consulting your doctor.

The 10 milligrams tablet may be taken with or without food, while the 15 milligrams and 20 milligrams tablet should be taken with food. If you have any questions about how to take Xarelto, ask your doctor or pharmacist.

If you are unable to swallow whole tablets, you can crush the tablet and mix it with applesauce, but do not prepare a supply for future use. If you are giving this medication through a tube into the stomach, ask your health care professional for detailed instructions on how to properly mix and give it.

The dosage and length of treatment is based on your medical condition and response to treatment. For children, the dosage is also based on weight. Take Xarelto regularly at the same time(s) each day to get the most benefit from it.
4404

Spironolactone for hair loss| Dr Dray
Spironolactone for hair loss| Dr Dray Side Effects 3 Views • 5 months ago

Dermatologist discusses spironolactone for hair loss in women. Before and after spironolactone for hair loss pictures are shown. I discuss side effects of spironolactone and dosages of spironolactone for hair loss.

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3 warnings for using yarrow
3 warnings for using yarrow Side Effects 3 Views • 5 months ago

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Yaz Side Effects Lawyer - Andy Bederman-of Greenberg & Bederman
Yaz Side Effects Lawyer - Andy Bederman-of Greenberg & Bederman Side Effects 4 Views • 5 months ago

Yaz Lawyer
Yaz Health Alert
Hello. I'm Andrew Bederman of the law firm of Greenberg and Bederman, which practices in the Washington, DC Metro area.

It's no secret that every birth control pill has a small element of risk. One of the acting ingredients in almost every oral contraceptive on the market is a hormone called progestin, which works in combination with estrogen to both prevent the egg from dropping and to prevent sperm from moving into the uterus.

The use of progestin in birth control pills has been shown in some rare cases to increase the risk of blood clotting among some women who use them. The numbers of these cases have been small enough over the years to make the use of progestin an acceptable risk. But the Bayer Corporation has not only put an oral contraceptive on the market that dramatically increases the odds of blood clotting, but has also engaged in advertising that downplayed the risks involved.

The pills in question are sold under the names Yaz, Yasmin, and a generic version called Oscella. These contraceptives were marketed as pills that can not only prevent pregnancy, but can also prevent acne and symptoms of PMS. The FDA cited Bayer this year for running misleading television commercials and last month for not following proper quality-control procedures at a plant that makes hormone ingredients. But the significant problem with Yaz, Yasmin and Oscella is that the key ingredient is a synthetic variation of progestin called drospirenone, which has been shown to increase the level of potassium in the blood and therefore increases the risks of blood clotting.

Yaz and Yasmin have received a litany of complaints from users and sanctions and penalties from the Food and Drug Administration. Between 2004 and 2008, the FDA has received fifty separate reports of deaths among women who were using either Yaz or Yasmin. The FDA has forced Bayer to change its advertising for these pills because they failed to adequately mention the higher risks of blood clotting and other very real medical dangers. These reports of deaths and injuries have caused the FDA to start a study comparing the risks of clotting and strokes between Bayer’s line of contraceptives and others that are on the market, mainly because they believe Bayer's initial study to be faulty.

It isn't only in America where these pills are having a detrimental effect on the lives of the women who use them. The medical regulatory board in Switzerland is currently investigating Yaz and Yasmin due to the death of a young woman who died of a pulmonary embolism. She had been taking Yaz for ten months.

Since these contraceptives have been put on the market, more and more women who use these pills have come forward to the Food and Drug Administration with stories of severe injuries due to strokes, pulmonary embolisms and heart attacks. The frequency of these reports has increased to the point where they can't be ignored or written off as “rare birth control side effects." And we believe the fact that Bayer advertised these products so heavily without properly warning potential users of these very real dangers was reckless and irresponsible.



The birth control pill, Yasmin, and it's smaller cousin YAZ, may contribute to a higher risk of cardiovascular problems including blood clots, stroke, and death.

Recent studies published in the British Medical Journal reveal that women who use Yaz™ or Yasmin™ oral contraceptives are more than twice as likely to suffer serious health complications than women using other oral contraceptives. Yaz™ and Yasmin™ have been linked with the following serious health complications:

heart attack
stroke
organ failure
gall bladder disease
blood clots/deep vein thrombosis
pulmonary embolism
If you have taken Yaz™ or Yasmin™ and have suffered a serious health consequence, you may be entitled to compensation from the pharmaceutical company.

For a free legal birth control consultation in Maryland, please call (301) 589-2200, ifin Washington D.C. Please call (202) 833-2200, or if in Virginia please call (888) 926-8583, or fill out our free birth control consultation form.

EMT/Paramedic Medication Notecards || Hydromorphone
EMT/Paramedic Medication Notecards || Hydromorphone Side Effects 8 Views • 5 months ago

Thanks for watching the video Dilaudid in EMS!

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Strokes in EMS || Recognition is key!
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How to Write a Stroke Narrative in EMS || Stroke DCHART Made Easy! (Example Included)
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BIG EMS MISTAKES!! || HOW TO HANDLE WHEN YOU MESS UP IN EMS
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WHY I TOOK ALL MY PREVIOUS VIDEOS DOWN || HARD TO ADMIT!
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EMS Q&A || WHAT SHOULD I STUDY TO PASS THE NREMT? HARDEST PART OF EMS? MANAGEMENT OF DKA?
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HOW TO ROCK YOUR PARAMEDIC INTERNSHIP | TOP TIPS FOR SUCCESS
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EMS IV INSERTION EXAMPLE || EMS SKILLS
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DIFFERENT EMS CAREERS | 30 WAYS TO USE YOUR EMS LICENSE
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WHAT I WISH I WOULD HAVE K.tNOWN BEFORE I WENT INTO EMS || LOSING FRIENDS
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ISOSORBIDE DINITRATE   - Generic Name , Brand Names, How to use, Precautions, Side Effects
ISOSORBIDE DINITRATE - Generic Name , Brand Names, How to use, Precautions, Side Effects Side Effects 1 Views • 5 months ago

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Vital information, Dosage info,
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Side Effects, Other Drugs Will Affect,
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19. BIOSTATISTICS – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
20. PATHOLOGY – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
21. NURSING EDUCATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
22. HOSPITAL MANAGEMENT AND HEALTH CARE ADMINISTRATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
23. NURSING RESEARCH – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
24. NURSING FOUNDATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
25. PHARMACOLOGY – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
26. PUBLIC HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
27. INTERNATIONAL DAYS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
28. NURSING - TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
#medicalknowledgeonline

The Worst Nausea in Existence?! | Lithium Medication Review
The Worst Nausea in Existence?! | Lithium Medication Review Side Effects 3 Views • 5 months ago

LITHIUM DRUG REVIEW!

I'm so excited to share my review of this amazing drug with you! Reviewing lithium is something I've wanted to do for a long time, so finally having this out there is WILD to me!

As promised... "How to Take Lithium Without Throwing Up" -
https://www.youtube.com/watch?v=evMku1Qlapk

Other Medication Reviews I've Done:

ZYPREXA/OLANZAPINE - https://www.youtube.com/watch?v=K9qziqMq9CQ&t=187s
SEROQUEL/QUETIAPINE - https://www.youtube.com/watch?v=aJHVF--TmzY
LAMICTAL/LAMOTRIGINE - https://www.youtube.com/watch?v=Uan_1-GLHHY&t=2s

My "Let's Talk Meds" Playlist - https://www.youtube.com/watch?v=K9qziqMq9CQ&list=PL9nV72zhqX-BmMv9tMPXplmnxw6pJbbfF

Paper:
"A History of Lithium Therapy" - https://www.notion.so/The-Hist....ory-of-Lithium-Thera

ALL MY LINKS: https://linktr.ee/schizokitzo

SCHIZOKITZO PROJECT LINKS (AKA WHERE TO FOLLOW ME AND SAY HI):
YouTube (hi): https://www.youtube.com/schizokitzo
Instagram: https://www.instagram.com/schizokitzo/
Facebook: https://www.facebook.com/schizokitzo
Twitter: https://twitter.com/SchizoKitzo

MY OTHER PROJECTS:
The Facebook Page for The Bees™: https://www.facebook.com/therealmadamebee
My Bee Aesthetic Instagram: https://www.instagram.com/beespoke_girl/

Disclaimer: I am not a qualified mental health professional. This channel exists for educational purposes, and I do my best to provide accurate and up-to-date information. In order to create content, I combine scientific resources (peer reviewed studies and easy-to-understand articles) and my own personal experiences/advice. I seek to make complicated topics easy to understand, but I am no substitute for a doctor, therapist, or other qualified mental health professional.

#schizoaffectivedisorder #mentalhealth #lithium

Xolair (omalizumab): Uses, How It Works, and Common Side Effects
Xolair (omalizumab): Uses, How It Works, and Common Side Effects Side Effects 3 Views • 5 months ago

Xolair is used to treat types of allergic asthma, nasal polyps, chronic hives, and to reduce the risk of severe food-related allergic reactions. It should not be used for asthma attacks or the emergency treatment of allergic reactions.

Learn more:
https://www.drugs.com/xolair.html

It was first approved by the FDA in 2003.

This medication is an anti-IgE antibody. It works by blocking the binding of IgE to receptors on cells, which in turn stops the release of the chemicals responsible for allergy symptoms.

Xolair is given as an injection under the skin every 2 to 4 weeks, depending on the condition. The first dose should be given under the supervision of a healthcare provider in case of a life-threatening allergic reaction.

Common Xolair side effects include joint pain, tiredness, bone fractures, stomach pain, dizziness, itching, skin rash, headache, earache, and injection site reactions. Side effects vary depending on the condition being treated and the age group of the patient.

This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Always consult with your healthcare provider.

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