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You're Taking the WRONG Vitamin B12: Methylcobalamin vs. Cyanocobalamin Side Effects 3 Views • 5 months ago

You're Taking the WRONG Vitamin B12: Methylcobalamin vs. Cyanocobalamin: In this video, we will explore how to choose the right vitamin B12 for you. Methylcobalamin vs. Cyanocobalamin
#DrJedosaThePharmD

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SUMMARY:
Many people don’t realize that not all B12 supplements are created equal and choosing the wrong one could mean poor absorption, wasted money, and even health risks.
In this video, I break down the key differences between methylcobalamin and cyanocobalamin, explain which one your body actually needs, and help you make the best choice for your health.

0:00- Intro: Vitamin B12: Methylcobalamin vs. Cyanocobalamin
1:02- Why Is Vitamin B12 So Important?
1:58- Types of Vitamins B12 Methylcobalamin vs. Cyanocobalamin
3:25- So which B12 Works Better?
5:08- How to Choose the Right Vitamin B12

Other Videos to Watch:
7 Powerful Nutrients to Strengthen Your HEART After 50: https://youtu.be/pVevual_hkw
Vitamin B12 Explained: Why Your Body Desperately Needs It Now!: https://youtu.be/6_7Wa1SUzsU
Vitamin B12 Deficiency Symptoms That You Should Never Ignore!: https://youtu.be/Glc7sXoxi64
Fish Oil (Omega-3) Explained: https://youtu.be/8BqW5-Y6CT4
7 Vitamins and Supplements to Clean CALCIUM out of Your ARTERIES: https://youtu.be/P0URKea9gSo
6 BEST Vitamins and Supplements to REMOVE PLAQUE From Your ARTERIES: https://www.youtube.com/watch?v=SG2TNm_n9f0&list=UULFKUyy-K_A8wq2U71WKg69gg
7 BEST Vitamins and Supplements to Increase BLOOD FLOW and Circulation: https://youtu.be/MKQ0fFb8pJk
Top 4 Powerful Vitamins to Lower Your Bad CHOLESTEROL Naturally: https://youtu.be/bLq0IkVFJ94

***Disclaimer:
This channel does not offer any medical advice. These videos and all comments are provided solely for educational purposes and are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Consult your doctor or another qualified healthcare provider if you have any questions about a medical condition. In addition, videos on this channel may contain information on the use of agents that have not been approved by the Food and Drug Administration of the United States (FDA). Dr. JedosaThePharmD does not advocate for the use of any unapproved agents.

Thanks for watching. I hope this video helps you understand how to choose the right vitamin B12 for you. Methylcobalamin vs. Cyanocobalamin

The Best Type of Vitamin B12: Cyanocobalamin or Methylcobalamin? Side Effects 3 Views • 5 months ago

Cyanocobalamin versus methylcobalamin: For prevention and treatment of vitamin B12 deficiency, cyanocobalamin in chewable, sublingual, or liquid forms (rather than in a multivitamin) is best under most circumstances.

New subscribers to our e-newsletter always receive a free gift. Get yours here: https://nutritionfacts.org/subscribe/

Whoa, that video was packed to the hilt. The dosage needed to treat B12 deficiency, how oral is better than injectable, why the cheaper form (cyanocobalamin) is superior to the more expensive form (methylcobalamin), why you can’t just take it in a multivitamin because of the analogs, and you shouldn’t just take it in a pill you just swallow (because it needs to mix with that saliva protein), and then with the toothpaste thing totally coming out of left field.

I mentioned my book, How Not to Diet, which you can find out more about here (https://nutritionfacts.org/how-not-to-diet/). It’s funny how I said it was my “last” book, not aware at the time I recorded it that little did I know I’d have a whole new book out by then out of nowhere. How to Survive a Pandemic (https://nutritionfacts.org/how....-to-survive-a-pandem out now in softcover, audiobook (read by me), and e-book form.

This is the last in a 5-video series on B12. You can find all of these videos in a digital download here (https://drgreger.org/collectio....ns/downloads/product along with two additional videos that will be coming out in a few months the potential for B12 side-effects.

If you missed any in this series, check out:
• The Symptoms of Vitamin B21 Deficiency (http://nutritionfacts.org/vide....o/the-symptoms-of-vi
• The Optimal Vitamin B12 Dosage for Adults (http://nutritionfacts.org/vide....o/the-optimal-vitami
• Healthiest Food Sources of Vitamin B12 (http://nutritionfacts.org/vide....o/healthiest-food-so
• The Optimal Vitamin B12 Dosage for Kids, Pregnancy, and Seniors (http://nutritionfacts.org/vide....o/the-optimal-vitami

Have a question about this video? Leave it in the comment section at http://nutritionfacts.org/vide....o/the-best-type-of-v and someone on the NutritionFacts.org team will try to answer it.

Want to get a list of links to all the scientific sources used in this video? Click on Sources Cited at https://nutritionfacts.org/vid....eo/the-best-type-of- You’ll also find a transcript and acknowledgements for the video, my blog and speaking tour schedule, and an easy way to search (by translated language even) through our videos spanning more than 2,000 health topics.

If you’d rather watch these videos on YouTube, subscribe to my YouTube Channel here: https://www.youtube.com/subscr....iption_center?add_us

Thanks for watching. I hope you’ll join in the evidence-based nutrition revolution!
-Michael Greger, MD FACLM

Captions for this video are available in several languages; you can find yours in the video settings. View important information about our translated resources: https://nutritionfacts.org/translations-info/

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THE TRUTH ABOUT CRESTOR SIDE-EFFECTS: MUSCLE ACHES, DIABETES AND MEMORY LOSS Side Effects 3 Views • 5 months ago

Rosuvastatin is a type of Statin drug that works by reducing the amount of blood cholesterol produced in the liver. Rosuvastatin isn't suitable for everyone and we will discuss who should and who should not take Rosuvastatin, the potential side-effects in some people and the most commonly asked questions in my clinic.

https://youtu.be/XVIg4asMqYg
https://youtu.be/k4dyxULRlvM
https://youtu.be/-hC1WGEy11Q
https://youtu.be/5cpN9VPg1TU

Clinical Data:

The New England Journal of Medicine Article (SATURN Trial):
https://www.nejm.org/doi/pdf/1....0.1056/NEJMoa1110874

FDA Drug Safety Communication:
https://www.fda.gov/drugs/drug....-safety-and-availabi

Timeline:
00:00 Introduction
00:50 What is Rosuvastatin?
01:30 What is Cholesterol?
02:41 How does it work?
03:18 How long does it take to work?
03:50 What is the correct dose?
04:39 How do you take it?
05:01 Is there any food or drink you should avoid?
05:14 Can you drink alcohol?
05:27 Does it interact with any other medicines?
06:43 Who may or may not be able to take Rosuvastatin?
07:35 What are the common side-effects?
07:58 What are the serious side-effects?
09:24 What is the difference between Atorvastatin and Rosuvastatin?
10:38 Are my muscle aches being caused by Rosuvastatin?
11:05 Taking rosuvastatin will increase the risk of Diabetes?
11:48 Can Rosuvastatin cause memory loss?

#rosuvastatin #crestor #statins

*ABOUT THIS VIDEO*
This video explains how Rosuvastatin (CRESTOR) belongs to a a group of drugs called HMG CoA reductase inhibitors, or "statins." Rosuvastatin is used together with diet to lower blood levels of "bad" cholesterol (low-density lipoprotein, or LDL), to increase levels of "good" cholesterol (high-density lipoprotein, or HDL), and to lower triglycerides (a type of fat in the blood).
Rosuvastatin is used in adults to slow the progression of atherosclerosis (a build-up of plaque in blood vessels that can block blood flow). It is also used to lower the risk of stroke, heart attack, and certain other heart complications in men and women who have coronary heart disease or other risk factors.
This video also explains how to take Rosuvastatin, as it can be taken as a single dose at any time of day, with or without food. Choose a time of day that will work best for you, and then take the medicine at the same time each day.
In addition the video explains, who may or may not be able to take it, which medications can interact with Rosuvastatin, and common side effects and serious side effects.

Disclaimer: The videos posted will be for general informational purposes only. They should not be used to self-diagnose or a substitute for a medical exam, cure, treatment, diagnosis, prescription, or recommendation. You should not make any changes to your health regimen or diet before first consulting a doctor.

The Dangers of STATINS & GRAPEFRUIT | A DOCTORS Guide | Increased Side Effects Side Effects 3 Views • 5 months ago

In this video, we explore the interaction between statins and grapefruit. Statins are a commonly prescribed medication used to lower cholesterol levels, but what happens when you consume grapefruit while taking statins? You'll find out that some statins are more affected by grapefruit than others. We delve into the science behind this interaction and provide some tips on how to safely manage your medication and diet. Watch now to learn more!

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#statin #statins #cholesterol #cholesterolmanagement #PatientInfo

Grapefruit juice affects certain statins more than others:

Large effect:
- atorvastatin (Lipitor)
- lovastatin (Mevacor)
- simvastatin (Zocor)

Little or no effect:
- fluvastatin (Lescol)
- rosuvastatin (Crestor)
- pravastatin (Pravachol)

..................

TIMESTAMPS:

00:00 Intro
00:11 Statins & Grapefruit The Interaction
01:12 Side Effects - Rhabdomyelisis & Liver Injury
00:43 Personal History of Asthma
02:03 Is a small amount ok?
02:59 Outro
03:06 Legal Disclaimer
03:11 End Screen

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Further Reading - Resources for Patients

NHS - Does Grapefruit Affect my Medication
https://www.nhs.uk/common-heal....th-questions/medicin

......................

Last updated 16th July 2023

Next review date: 16th July 2026

Author: Dr Andrew Hart Pinto

Internally peer-reviewed: Dr Najeebah Jaunbocus 16th July 2023.

......................

Patient Information videos produced by GMC registered/Certified Doctors.

Videos cover definitions, aetiology, symptoms, clinical features, management, prognosis and complications of various medical topics.

Our clinicians:
1. Dr A. Hart-Pinto MBChB (Hons) BSc (Hons) MRCS
2. Dr Najeebah Jaunbocus MBChB MRCGP

Our clinical information aims to adhere to the standards set by the NHS in their Standard for Creating Health Content guidance and that agreed upon by YouTube Health.

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JHP Medical UK uses stock footage within its videos. We do not believe, nor wish to imply that individuals identifiable within stock footage suffer from the condition being discussed. If you do not want to be included in our videos, don't hesitate to contact our team via [email protected], and we will remove the footage.

......................

Background Music Licenced from Epidemic Sound

Want to try Epidemic Sound for your videos, click the link:
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....................

Legal Disclaimer

JHP Medical UK contains content generated by our doctors. Content provided via YouTube is for general information purposes ONLY. Information videos are not produced to provide individualised medical advice. Medical education videos on JHP Medical UK are not a substitute for professional medical advice, diagnosis or treatment. NEVER ignore professional medical advice because of something you have heard here. ALWAYS consult your doctor regarding any concerns about your condition or treatment.

Reasonable effort shall be made to update the information on the JHP Medical UK YouTube channel. However, we make no representations, warranties or guarantees, whether express or implied, that the content is accurate, complete or up-to-date.

Rosuvastatin Explained: 6 Surprising Side Effects of Rosuvastatin You Should Know Side Effects 3 Views • 5 months ago

Are you taking rosuvastatin? 6 Side Effects of rosuvastatin You Must Know. In today's video, we will discuss the side effects of rosuvastatin 5mg, 10mg, 20mg, and 40mg.
#DrJedosaThePharmD

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Other Videos to Watch:
Taking Lisinopril? 5 Things You Must Avoid If You Are Taking Lisinopril: https://youtu.be/p5bt3KsT_IE
Taking Atorvastatin? 5 Things to Avoid If You Are Taking Atorvastatin Now: https://youtu.be/BxOClBUUjr4
STATIN Medications Alert: 6 BAD Side Effects You Must Know [Atorvastatin, Rosuvastatin, Simvastatin]: https://youtu.be/xgVn1p_bAVI
Taking Simvastatin? 5 Things You Must Avoid If You Are Taking Simvastatin: https://youtu.be/8ZdQ1QjnLoQ
Taking Amlodipine? 5 Things to Avoid If You Are Taking Amlodipine Now:https://youtu.be/wvKYph5rH6Y
What Are The Side Effects of AMLODIPINE 10mg 5mg 2.5 mg and How to Reduce Side Effects?:https://youtu.be/PdJ7FPRwn-k
3 Powerful Drinks to Lower BLOOD PRESSURE Naturally:https://youtu.be/wOg3SNipFm0
Why Your BLOOD PRESSURE Reading is WRONG!: https://youtu.be/DBM1owhQ4D0
How to Lower BLOOD PRESSURE Naturally with High Potassium Foods:https://youtu.be/-suxYifgvEA
Low Potassium Alert: Signs and Symptoms That You Shouldn't Ignore!: https://youtu.be/USP85kOo-fI
HIGH BLOOD PRESSURE Warning Signs and Symptoms: https://youtu.be/2Vtvj67qGi0

Summary:
Are you taking rosuvastatin? Understanding the potential side effects of rosuvastatin, a commonly used medication for high cholesterol, is crucial. In this video, you will discover the potential side effects of rosuvastatin, including muscle pain, headaches, digestive issues, an increased risk of diabetes, liver damage, and rhabdomyolysis, which is a fancy word for muscle breakdown.

Here are 6 side effects of rosuvastatin you must know:
0:00- Intro: What is rosuvastatin and how does it work?
1:00- Headache
1:59- Muscle Pain and Weakness
3:18- Joint Pain
4:23- Stomach Pain
5:24- Muscle Damage
6:28- Risk Of Diabetes
7:30- Liver damage and memory loss

***Disclaimer:
This channel does not offer any medical advice. These videos and all comments are provided solely for educational purposes and are not intended to be a substitute for professional medical advice, diagnosis, or treatment. Consult your doctor or another qualified healthcare provider if you have any questions about a medical condition. In addition, videos on this channel may contain information on the use of agents that have not been approved by the Food and Drug Administration of the United States (FDA). Dr. JedosaThePharmD does not advocate for the use of any unapproved agents.

Thanks for watching. I hope this video helps you understand and learn about the side effects of rosuvastatin 5mg, 10mg, 20mg, and 40mg.

What Are The Side Effects Of Secukinumab? - Pharmaceutical Insights Side Effects 3 Views • 5 months ago

What Are The Side Effects Of Secukinumab? In this informative video, we will discuss the side effects associated with Secukinumab, a medication commonly prescribed for various inflammatory conditions such as psoriasis, psoriatic arthritis, and ankylosing spondylitis. Understanding the potential side effects is essential for anyone considering this treatment. We will cover both common and serious side effects, including symptoms related to the upper respiratory tract, injection site reactions, and the risk of infections due to the medication's impact on the immune system.

Additionally, we will highlight less common side effects that may occur and emphasize the importance of monitoring for any concerning symptoms. If you or someone you know is using Secukinumab, this video will provide valuable information on what to watch for and when to seek medical advice.

Stay informed and take charge of your health as we break down everything you need to know about Secukinumab and its side effects. Don’t forget to subscribe to our channel for more helpful discussions on medications and health topics.

⬇️ Subscribe to our channel for more valuable insights.

🔗Subscribe: https://www.youtube.com/@Pharm....aceutical-Insights/?

#Secukinumab #MedicationSideEffects #PsoriasisTreatment #PsoriaticArthritis #AnkylosingSpondylitis #InflammatoryConditions #InjectionSiteReactions #RespiratorySymptoms #AllergicReactions #InfectionRisks #HealthAwareness #PatientSafety #MedicationManagement #HealthcareTips #ChronicIllness

About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

All You Need to Know about Biologics - How They Work, When to Use Them and The Common Side Effects Side Effects 3 Views • 5 months ago

What are biologics, how do they work, what are the most common classes of biologics and what are the most common side effects of these medications. All discussed in detail in this video, by rheumatologist Dr. Diana Girnita
#biologics #rheumatoidarthritis #psoriaticarthritis #ankylosingspondylitis

Chapters
0:00 Intro
01:22 What are Biologics?
02:13 How do “Biologics” work?
03:09 What are the most common classes of biologics used in rheumatology?
04:01 TNF inhibitors ( #humira #enbrel #cimzia )
04:40 IL-6 inhibitors ( #actemra #tocilizumab )
05:04 IL-17 inhibitors ( #taltz #cosentyx )
06:00 Laboratory tests before biologics ( #tuberculosis screening )
06:53 What should you consider in preparation for biologics therapy?
07:14 What are the most common risks associated with the use of biologics?
07:34 #infections and biologics
08:43 #cancer and biologics

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Please share with others that might benefit from this knowledge.
Want to learn more from Dr. Diana Girnita and Rheumatologist OnCall?

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*Please note - we do not provide medical advice, opinions or diagnosis via email, phone or social media messaging.We are seeing patients in multiple US states (currently 10 states). Please check our website to see if we are evaluating and treating patients in your state.*

👩🏻‍⚕️ About me:
Dr Diana Girnita is a double board certified physician in rheumatology and internal medicine. She completed a PhD in immunology, a postdoctoral fellowship at Harvard University, immunology fellowship at University of Pittsburgh and rheumatology fellowship at University of Cincinnati. Dr. Girnita graduated from the Nutrition Science course from Stanford University and a Mindfulness course from The University of Massachusetts; She is the founder & CEO of Rheumatologist OnCall, a practice focused on broadening access to rheumatology and offering patients an integrative medicine approach.
Dr. Girnita teaches patients about autoimmune disease, arthritis and also helps them customized their treatment plans to incorporate the proper nutrition, exercise and management of stress: "You have a disease, but YOU are not the disease"

** The information in this video is not intended nor implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information, contained in this video is for general information purposes only and does not replace a medical consultation. Any comments and/or recommendations made in the comment section by anyone other than Rheumatologist OnCall does not reflect our opinion or recommendation.**

Best Psoriatic Arthritis Treatments Side Effects 3 Views • 5 months ago

Psoriatic Arthritis Treatment new treatments
Discover the latest advancements in treating Psoriatic Arthritis (PsA) and Psoriasis. This informative video explores the efficacy, safety, and impact on patient outcomes of new and promising treatments, including biologic agents, targeted synthetic drugs, and novel therapeutic approaches. Stay up-to-date with the most effective strategies to manage these chronic inflammatory conditions and improve quality of life.
#psoriaticarthritis #psoriasis #psoriasistreatment #treatment #biologics

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🎥 watch more: https://www.youtube.com/@rheumatologistoncall
🩺 Contact us: [email protected]
or access our website

👩🏻‍⚕️ About me: Dr. Diana Girnita is a double board-certified physician in rheumatology and internal medicine. With a Ph.D. in immunology and training at Harvard and top universities, she founded Rheumatologist OnCall, offering integrative medicine to broaden rheumatology access. With a focus on personalized treatment, Dr. Girnita incorporates proper nutrition, exercise, and stress management. Experience her passion for helping patients with autoimmune disease and arthritis. This video provides general information and is not a substitute for medical advice. Views expressed in comments do not reflect the opinion of Rheumatologist OnCall. Important Notice: Medical advice, opinions, or diagnosis cannot be provided through email, phone, or social media. Our clinic serves patients in various US states. Check our website to confirm whether we accept patients in your state."

Cosentyx 101: Uses, Side Effects Interactions (Also ... Be Careful Taking With These 2 Conditions) Side Effects 3 Views • 5 months ago

11 Natural Therapies (Outside of Drugs And Surgery) That Actually Work [free checklist]: https://curtis-alexander.com/

What Is Cosentyx Used To Treat?

Cosentyx is one of the newer injectable medications on the market that's used to treat a number of different inflammatory-based conditions.

Those include Plaque Psoriasis, Psoriatic Arthritis, Ankylosing Spondylitis, and Axial Spondyloarthritis

Cosentyx MOA (Mechanism of Action)

I mentioned above that Cosentyx works by decreasing inflammation. Specifically, it does that by blocking interleukins.

The end result is a decrease in the release of cytokines and chemokines. These are substances that are involved in the inflammatory process.

But remember inflammation can be bad when there's too much of it. But it's also one of the first steps in your immune response which is a good thing.

So even though blocking interleukins sounds like a good thing in the late stages - it can also bring on some side effects which I’ll get to in a second.

How Is Cosentyx Dosed?

The dosing of Cosentyx changes a lot based off what you're treating.

But by and large you're going to see Cocentyx started with a loading dose and then moved to a maintenance dose.

It's a subcutaneous injection and the loading dose is usually 300 mg subcutaneously once a week for the first 5 weeks.

Then you move on to the maintenance dose which can vary from 150 mg to 300 mg every 4 weeks.

One of the downsides of Cosentyx is that to get the 300 mg dose requires two injections because the drug is only available in 150 milligram strength.

How Long Does It Take To Start Working?

This is a really good question and can vary from person to person.

But I like to use the 3 months rule of thumb. That means for most people you'll start noticing a difference by three months out.

In studies some people have noticed the difference is early as one month. Other people require more like 16 weeks before they see a difference it’s something you definitely have to be patient with.

What Are The Side Effects of Cosentyx?

The most common side effect you'll see with it by a long shot is increased infection rates.

This can happen in anywhere from 29% to 48% of people in studies. The types of infections can vary from the herpes virus, staph and upper respiratory tract infections.

Other less common side effects are going to be diarrhea in 3% - 4% of people. Headaches occur in around 2% of people.

It's important to remember that some people can actually see their cholesterol levels increase. But this only happens in about 2% of people.

The one thing I want to point out if you have Crohn's disease or ulcerative colitis Cosentyx can actually make those things worse. It's a very small chance that this will happen but it's something important for you and your doctor and all about.

What About Weight Gain or Hair Loss With Cosentyx?

In studies there weren’t any reports of weight gain or hair loss with Cosentyx. In fact, you're more likely to see weight loss because some of the side effects can be diarrhea and infections. So people are more likely to not be eating less when taking it.

Is It Safe to Take With My Other Medications?

A general rule of thumb here is that you don't want to take it with anything that can lower your immune system. Couple of examples would be cyclosporine or tacrolimus.

What About Monitoring?

Before your doctor starts you on this they're going to make sure to get a tuberculosis test done.

They're also going to keep an eye out for any signs or symptoms of irritable bowel disease.

Like a lot of other injectable medications Cosentyx can get pretty expensive - especially if you don't have good insurance.

So I'm going to make sure to include a link to their website where they talk about some of their financial assistance programs.

These are going to vary based off whether you can qualify for them or not. But it's worth having the information available so at least you can check into it: https://www.cosentyx.com/treatment-cost

Concerta Review: ADHD Miracle...or Overrated Hype? Side Effects 3 Views • 5 months ago

Let's take a deep dive into Concerta, a widely prescribed medication for ADHD treatment. With a special interest in ADHD and its management, Dr. Sulman Aziz Mirza provides valuable insights into Concerta's unique features, benefits, and potential side effects, as well as some of the controversies around Concerta suddenly "not working" anymore...

Don't miss out on this comprehensive guide to understanding Concerta and its role in ADHD treatment. If you or a loved one is considering Concerta or any other ADHD medication, this video provides crucial information to help you make informed decisions.

Be sure to like, share, and subscribe for more informative content on ADHD and mental health. Leave your questions and experiences in the comments section, and let's keep the conversation going!

Chapters
0:00 Intro
1:29 Concerta - psychopharmacology
2:31 What's special about OROS?
4:54 Adverse effects
6:14 What to expect on Concerta
7:58 Take home message

#Concerta #ADHD #MentalHealth #Psychiatry #Methylphenidate
__________________________________________
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DISCLAIMER: This video is purely informational and educational and does not constitute medical advice and/or recommendations. Use of information is at your own risk, and expresses my own personal views and opinions, not those of any of my employers. Sulman Aziz Mirza, MD will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness, or death.

In the event of any medical emergency or safety concerns, please go to your nearest emergency department and/or call 911.

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Methylphenidate (Ritalin, Concerta) - Uses, Dosage, Side Effects and Safety - Doctor Explains Side Effects 3 Views • 5 months ago

In this video we will cover everything you need to know about Methylphenidate, also known as Concerta or Ritalin. This video is part of a video series on mental health problems. So for more mental health related videos check out this playlist:
https://www.youtube.com/playli....st?list=PLaG3Bo3L0gX

Generic name: Methylphenidate.
Brand names: Ritalin and Concerta.
Available as a tablets, modified release tablets and capsules.

How to use it?
- Tablet: swallow it whole with half a glass of water. It is possible to chew on the tablet or break it.
- Modified release tablet or a capsule: also take it with water, but don’t break it and do not chew on it. This can decrease its effectivity.
In addition it is advised to take Methylphenidate during a meal, as this can decrease your chances on side effects.

When to use it?
Methylphenidate has a stimulating effect on the central nervous system. It has properties similar to amphetamines. It can be used to treat ADHD, narcolepsy and it can be used during palliative sedation.

What is the correct dosage?
The precise dose will depend on your specific indication of use, the side effect you might experience ,the severity of your symptoms and the brand of methylphenidate you might be using.Therefore always use the precise amount and frequency your doctor prescribed you.

- However, when treating ADHD symptoms with regular tablets in children older than 6 years or in adults: a usual starting dose would be 5mg 2x/day. If necessary this can be slowly increase up to a maximum dose of 60mg/day.
- Here it is important to note, that the dosages of modified release tablets and capsules may be different.
- When treating narcolepsy in adults, your doctor might prescribe a dose of 10mg/ 2-3 per day.

What are common the side-effects?
- Very common (10%): insomnia, nervousness, headache, palpitations, decreased appetite, nausea and a dry mouth.
- Common (1-10%): upper respiratory tract infection, shortness of breath, decreased appetite, weight loss, aggression, agitation, irritability, restlessness, anxiety, panic attack, stress, depression, decreased libido, erectile dysfunction, tics, tremor, mood swings, fast heart rate, high blood pressure , upset stomach, vomiting, diarrhoea, cough, sore throat, rash, itching, fever and fatigue.
Uncommon (0.1-1%): Hypersensitivity reactions, psychotic disorders, suicidal ideas, hallucinations, blurred vision, dry eyes, chest pain, hot flush, constipation, muscle twitching and muscle tension.
- Rare (0.01-0.1%): mania, libido disorder, disorientation, chest pain, visual impairment and menstrual disorder.

Safety:
First of all be careful to combine methylphenidate with alcohol. As this might increase its dazing effects.
In addition, it can be dangerous to drive while using this drug. As it can cause you to become drowsy, sleepy and/or dizzy. If you experiencing any of these side effects than please do not drive. This is especially true for the first few weeks you are using it.
Furthermore, methylphenidate can have interactions with other drugs your are taking. always discuss this with your prescribing doctor.
Unfortunately, the effects of methylphenidate during pregnancy or while breastfeeding are not studied properly. Therefore it could be dangerous and its usages should be avoided. Always discuss this with your personal doctor, as there might be some exceptions.

- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -

I want to give special thanks to my sponsors on Patreon:
- Sebastian Houwing: Investor

Literature:
1: Farmacotherapeutisch Kompas. (2021). Methylfenidaat
2: Apotheek.nl (2021). Methylfenidaat

* The images in this video are used for educational purposes only. Most of the images and videos in this video come from https://www.canva.com/.

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COLCHICINE - - Generic Name , Brand Names, How to use, Precautions, Side Effects Side Effects 3 Views • 5 months ago

Colchicine for Gout - PART 3: 7 Ways to Try to Avoid Side Effects - Some Need-to-Know Info! Side Effects 3 Views • 5 months ago

PHARMACIST Fi shares 7 Top Tips to help you try to avoid colchicine toxicity side effects (such as diarrhea, nausea, vomiting, stomach or intestine area pain, throat pain, etc.) - which are thankfully much less common now that a lot of doctors are prescribing
*modern, smaller dose schedules for acute gout flare treatment,
*lower colchicine dose schedules for people with kidney or liver problems, and
*managing serious interactions with certain types of other medicines - by either stopping colchicine or significantly reducing the colchicine dose schedule (depending on which medicine is interacting with colchicine).

Here is the link to PHARMACIST Fi's video about potential colchicine side effects and medicine interactions to avoid: https://youtu.be/deO0BMqNwWM

It is also important to remember to:
*avoid eating grapefruit and avoid drinking grapefruit juice while taking colchicine
*never take more colchicine than the doctor advises to take, and
*only take colchicine if it has been prescribed for you and don't give your colchicine to other people (because some people must not take colchicine due to some types of medical conditions, or potentially lethal medicine interactions with certain types of medicines).

If the doctor's instructions about how to take colchicine could be interpreted more than one way, or if you forget exactly how the doctor advised to take colchicine, as soon as possible, ask your doctor:
*how much colchicine to take per dose, and
*how much time to leave between colchicine doses, and
*whether or not there is a date that you need to stop taking colchicine (this will depend on whether the aim is to treat an acute gout flare, or to try to prevent future gout flares - because the colchicine dose schedules for these 2 different aims are likely to be quite different).

Here is the link to PHARMACIST Fi's video 'Ways to Avoid Accidentally Taking Too Much of a Medicine': https://youtu.be/zxucLmKicOc
&
Here is the link to PHARMACIST Fi's video 'Ways to Avoid Forgetting to take Medicines': https://youtu.be/e_UWtmuDfuM

Here is the link to PHARMACIST Fi's 'Colchicine Part 1' video of important things to talk about with your doctor if you have been prescribed colchicine: https://youtu.be/N6jCa795bLg

Here is the link to PHARMACIST Fi's 'Gout and Medicines' playlist (including interesting new info about gout treatment in her '10 Things You May Not Know About Gout' series): https://www.youtube.com/playli....st?list=PLwyYRbsDY3j

Here is a link to the PHARMACIST Fi video about making a Medicines, Allergies & Contacts List, & what types of info about medicines to put on your Medicines, Allergies & Contacts List, so you can check it regularly before taking medicines, to try to take medicines the best way possible: https://youtu.be/6gveHPwmc9s

Colchicine brand names in the USA include: Colcrys, Mitigare, Gloperba; colchicine brand names in Australia include: Colgout, Lengout, Colcine.

INFORMATION FOR DOCTORS:
Here is a link to an example of a modern colchicine dose schedule for treatment of acute gout flare, for people with good kidney and liver function, in the 'Treatment of Gout Flares' section at the base of page 3 of the Colcrys Prescribing Information (Revised May 2020) available on the FDA website August 2023: https://www.accessdata.fda.gov..../drugsatfda_docs/lab

Please also note that for people who do have kidney impairment or liver impairment, colchicine dose schedules for treatment of acute gout flare are in the 'Treatment of Gout Flares' sections on page 8 and 9, respectively, in the Colcrys Prescribing Information document above.

The Australian Medicines Handbook 2023 (https://shop.amh.net.au/products/digital) has further advice for prescribers about colchicine dose schedules and interaction management, although a subscription fee is required to access its information.

We hope this video was helpful for you.
Please also read the disclaimer at the end of the video.

If you would like to support PHARMACIST Fi to produce more of these Medicine Safety videos, please consider making a purchase from her Official Store at: https://pharmacist-fi.myshopif....y.com/collections/al ,
or making a paypal donation to PHARMACIST Fi at https://www.pharmacistfi.com/donate

Colchicine for Gout - Part 2: Side Effects & Interactions - Some Need-to-Know Info! Side Effects 3 Views • 5 months ago

PHARMACIST Fi shares serious potential side effects to report (thankfully these are now much less common with modern dose schedules), & some potentially lethal medicine interactions to avoid, for a medicine called colchicine when it is taken for gout.

If you take colchicine for a medical condition other than gout, ask a doctor for advice about the info in this video or description section, as it may or may not be suitable for your medical condition.

Here is the link to the 'Gout & Medicines' playlist, including 2 more PHARMACIST Fi videos about colchicine (scroll down the playlist to find 'Colchicine for Gout Part 1 - Things to Talk About with Your Doctor', & 'Colchicine for Gout - How Does that Work?!'), plus videos about gout, & allopurinol (allopurinol is also commonly prescribed for people with gout, if it is suitable for them): https://www.youtube.com/playli....st?list=PLwyYRbsDY3j

The active ingredients of some medicines which PHARMACIST Fi lists on screen in this video (from 5 minutes 16 seconds, to 6 minutes 33 seconds) which interact seriously with colchicine, are taken from the article at this link: https://pubmed.ncbi.nlm.nih.gov/36522578/ (pages 227-233), and the 'strong CYP3A4 inhibitors' in the interactions section of 'Australian Medicines Handbook 2023'.

Here is a list of some other active ingredients which interact with colchicine to increase toxicity risk in a similar [but hopefully less major] way to the medicines PHARMACIST Fi listed in her video -
so, if you take any of the following medicines, ask your doctor for advice before taking colchicine for gout, as you may need a colchicine dose reduction to manage the interaction
*while being treated with one of the following medicines, and
*also for 2 weeks after being treated with one of the following medicines
(needing a colchicine dose reduction to manage an interaction with one of the following medicines is even more likely if you have a kidney or liver problem; doctors can find info about colchicine dose reduction in medicine prescribing information or the Australian Medicines Handbook 2023):
azithromycin
boceprevir
carvedilol
everolimus
fluconazole (commonly used antifungal medicine)
fluvoxamine
glecaprevir with pibrentasvir
isavuconazole
ledipasvir
letermovir
osimertinib
propafenone
quinidine
ranolazine
tacrolimus
tepotinib
ticagrelor
tolvaptan
vandetanib
velpatasvir
vemurafenib
venetoclax
voxilaprevir
Please note: medicines on the above list are not the only medicines which interact with colchicine in this way, so ask your doctor or pharmacist for a medicine interactions check.

Colchicine also has other types of interactions. Here are some examples of other interactions with colchicine (from Colgout brand colchicine product information for doctors):
*Alcohol increases risk of colchicine toxicity side effects like nausea, vomiting, diarrhoea, stomach or intestine pain, and increases gout flare risk by raising uric acid level
*Colchicine may increase risk of potential muscle side effects (like muscle tenderness or weakness) of some statin or fibrate medicines for cholesterol (e.g. simvastatin, atorvastatin, lovastatin, gemfibrozil, fenofibrate)
*Colchicine may increase risk of low blood cell production if taken with other medicines with this potential side effect
*Acidifying substances (like ammonium chloride, ascorbic acid (vitamin C), acid phosphates) may make colchicine less effective
*Alkalinizing substances (like sodium bicarbonate, potassium citrate) may increase the effect of colchicine
*Colchicine may increase the effect of medicines that make us sleepy, and alcohol
*Colchicine may increase the effect of adrenaline, dopamine, dobutamine, isoprenaline or ephedrine
*If colchicine is taken long-term, it may decrease absorption of vitamin B12, so ask your doctor for a blood test for vitamin B12 - to find out if you may need a vitamin B12 supplement
*The herbal medicine St John's Wort (Hypericum perforatum) may make colchicine less effective, by making our body get rid of colchicine quicker than usual; some types of medicines may interact with colchicine in this way

If you think you might have one of these interactions, ask a doctor for advice as soon as possible about whether any medicine changes may or may not be needed.
Please note: these are not all of the possible colchicine interactions, so ask a doctor or pharmacist for a medicine interactions check.

INFO FOR DOCTORS
Here is a link to Colcrys Prescribing Information on FDA website (revised 2020) with a modern colchicine dose schedule for treatment of acute gout flare for people with good kidney and liver function ('Treatment of Gout Flares', at base of page 3), plus schedules for people with kidney or liver impairment ('Treatment of Gout Flares' on pages 8 & 9, respectively): https://www.accessdata.fda.gov..../drugsatfda_docs/lab

We hope this video has been helpful for you.
Please also see disclaimer at the end of the video.

Miralax maximum = 7 days? Side Effects 3 Views • 5 months ago

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DISCLAIMER: This video is purely educational and does not constitute medical advice. The content of this video is my personal opinion and not that of my employer(s). Use of this information is at your own risk. Albert Chung, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness, or death.