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What Are The Potential Side Effects Of Using Diltiazem In A Hypertensive Crisis? Side Effects 3 Views • 5 months ago

What Are The Potential Side Effects Of Using Diltiazem In A Hypertensive Crisis? In this informative video, we will discuss the potential side effects associated with the use of diltiazem during a hypertensive crisis. Diltiazem, a calcium channel blocker, is often utilized for managing high blood pressure and certain heart rhythm issues in emergency situations. While it can provide rapid relief from dangerously high blood pressure, it is essential to be aware of the side effects that may accompany its use.

We will cover both common and serious side effects, including dizziness, headaches, and swelling, as well as more severe reactions such as low blood pressure and irregular heartbeats. Understanding these risks is vital for anyone who may be involved in managing a hypertensive crisis, whether as a patient, caregiver, or healthcare professional.

By the end of this video, you will have a clearer picture of what to expect when diltiazem is administered in critical situations. We aim to equip you with the knowledge needed to make informed decisions regarding hypertension management. Don’t forget to subscribe to our channel for more helpful discussions about hypertension and related health topics.

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#Hypertension #HighBloodPressure #Diltiazem #CalciumChannelBlockers #BloodPressureManagement #HeartHealth #MedicalEmergency #HealthRisks #PatientCare #MedicationSideEffects #CardiovascularHealth #EmergencyMedicine #HealthcareProfessionals #HypertensiveCrisis #MonitorHealth

About Us: Welcome to Hypertension Help Hub, your go-to channel for everything related to high blood pressure. Here, we provide clear and concise information on High Blood Pressure Basics, Causes of Hypertension, Symptoms, Blood Pressure Monitoring, and Lifestyle Changes for Hypertension. We cover essential topics such as the DASH Diet, Medications for High Blood Pressure, and effective strategies for managing stress to support heart health. Our goal is to equip you with practical tips for Hypertension Prevention and ways to take control of your well-being. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

What Are The Long-term Effects Of Diltiazem? - Pharmaceutical Insights Side Effects 3 Views • 5 months ago

What Are The Long-term Effects Of Diltiazem? In this informative video, we will discuss the long-term effects of diltiazem, a widely used medication for managing cardiovascular health. Diltiazem plays a vital role in treating conditions such as high blood pressure, heart disease, and irregular heart rhythms. We will cover how this medication functions within the body and its safety profile over extended periods of use.

Throughout the video, we will highlight key aspects of diltiazem, including common side effects and the importance of monitoring them with your healthcare provider. Understanding the potential benefits and risks associated with long-term use is essential for anyone considering or currently taking this medication.

We will also touch on the medication's impact on heart health, kidney and liver function, and other vital bodily processes. Regular check-ups and open communication with healthcare professionals are crucial in ensuring optimal outcomes when using diltiazem.

Join us for this engaging discussion on diltiazem and its long-term effects, and don't forget to subscribe to our channel for more informative content related to medicine and health.

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About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

This Is What Happens to Your Brain on Dilaudid (Hydromorphone) Dosage & Side Effects Side Effects 3 Views • 5 months ago

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Dilaudid's side effects can be dangerous. This video explores Dilaudid drug facts, use consequences, and interactions.

🌟 Explore the World of Dilaudid: Unveiling Its Effects and Risks 🌟

Welcome to our comprehensive guide on Dilaudid Side Effects! If you or a loved one has encountered this potent opioid pain medication, it's crucial to understand its nuances, potential risks, and the impact it can have on your life. Join us as we delve into the various facets of Dilaudid in this enlightening video.

🔍 Dilaudid Unveiled
Discover the origins of Dilaudid, a powerful opioid analgesic derived from morphine. Known by its brand name, Dilaudid, this drug is a double-edged sword—offering relief from severe pain but posing a risk of abuse and dependency.

💊 The Dark Side of Dilaudid Addiction
Learn about the intricate web of Dilaudid addiction. Explore the National Institutes of Health's insights into how repeated use alters the brain's structure, leading to dependence that permeates every aspect of life. Discover the thin line between therapeutic use and abuse.

🚨 Unmasking Dilaudid Side Effects
Delve into the typical side effects of Dilaudid, from nausea to constipation. Understand the importance of recognizing and addressing these effects promptly. We provide practical tips to mitigate issues like constipation and dizziness.

🔄 Long-Term Effects & Duration of Action
Uncover the potential long-term consequences of regular Dilaudid use. How does physical dependence develop, and what are the withdrawal symptoms? Explore the duration of action and the powerful pain relief that Dilaudid offers.

🌡️ Dilaudid's Potency & Comparison to Morphine
Get insights into Dilaudid's strength—approximately eight times more potent than morphine. Understand why it's crucial to dispense this opioid cautiously and only to those who can tolerate such potent medications.

🔬 Is Dilaudid an Opioid?
Addressing a common query: Is Dilaudid an opioid? Gain a clear understanding of hydromorphone as a semi-synthetic opioid agonist and the potential risks associated with its use.

🕵️ The Dangers Lurking on the Streets
Explore the ominous world of street names for Dilaudid and the risks associated with obtaining it outside legitimate channels. Understand the potential dangers of street-purchased opioids, including the frightening prevalence of fentanyl.

🧠 Dilaudid's Impact on the Body & Brain
Unravel the mysteries of how Dilaudid affects the respiratory system, induces a feeling of euphoria, and leads to tolerance and addiction. Gain insights into the withdrawal syndrome and its challenges.

💊 Dilaudid's Interaction with the Brain
Embark on a journey into the brain's response to Dilaudid. Understand how hydromorphone, the key ingredient, binds to opioid receptors, providing analgesia and altering the perception of pain.

🤔 The Itch Factor
Decode the enigma of itching as a Dilaudid side effect. Explore potential treatments for this discomfort and understand the precautions needed, such as avoiding certain drug combinations.

💪 Navigating Dilaudid Detox
Confront the reality of Dilaudid detox—a challenging but essential step toward recovery. Acknowledge the emotional, physical, and mental hurdles one may face during this process.
#DilaudidSideEffects #OpioidAwareness #PrescriptionDrugAbuse

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Pharmacology: Drugs for Heart Failure, Animation Side Effects 3 Views • 5 months ago

Mechanisms of actions of ACE inhibitors, Angiotensin receptor blockers (ARBs), Beta-blockers, Aldosterone receptor antagonists (ARAs), Digoxin, Ivabradine, Angiotensin Receptor-Neprilysin Inhibitor, ARNIs (sacubitril/valsartan), Diuretics, Vasodilators. Role of RAAS, sympathetic system and natriuretic peptide system in pathophysiology of Congestive heart failure (CHF) and rational for treatment of HF.

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Heart failure is when the heart is unable to pump effectively, called systolic heart failure; or unable to fill properly, called diastolic heart failure. In both cases, blood output is reduced. Ejection fraction is reduced in systolic heart failure, but typically preserved in diastolic heart failure.
The pathophysiology of heart failure involves a vicious cycle in which reduced cardiac output, as a compensatory response, activates the renin-angiotensin-aldosterone system (RAAS) and sympathetic system. However, these systems cause vasoconstriction, increase heart rate and blood pressure, making it even harder for the heart to pump. Increased aldosterone level also promotes ventricular remodeling, myocardial scarring, and vascular injury, worsening the disease.
On the other hand, the natriuretic peptide system is also activated. This system is protective to the heart. It promotes vasodilation, sodium and water excretion, and inhibits cardiac remodeling.
Most drugs used in heart failure therapy aim to inhibit RAAS and sympathetic activities, and/or promote the natriuretic system. Other drugs increase ventricular contractility or reduce water retention – a major heart failure symptom.
First-line therapy for patients with reduced ejection fraction typically includes an angiotensin-converting enzyme (ACE) inhibitor, and a beta-blocker.
- ACE inhibitors block the conversion of angiotensin-I to angiotensin-II in RAAS, thereby inhibiting RAAS activity. Common side effects include dry cough, headache, and hypotension. Rarely, ACE inhibitors may cause a swelling reaction known as angioedema.
- Angiotensin receptor blockers (ARBs) inhibit the effects of angiotensin-II. Their mechanism of action is similar to that of ACE inhibitors, but they do not usually cause a cough.
- Beta-blockers decrease heart rate by binding to β1-adrenergic receptor in the heart and blocking the sympathetic influences that act through these receptors. Adverse effects: hypotension, bradycardia and AV blocks.
- Vasodilators reduce blood pressure and are usually used for patients who cannot tolerate ACE inhibitors or ARBs.
- Diuretics are often prescribed to relieve fluid retention. Loop diuretics are most powerful and typically used for most patients. Thiazides are less effective, but they also have a vasodilation effect, and are thus preferred for patients with hypertension but only mild fluid retention.
- Aldosterone receptor antagonists block the action of aldosterone. Because aldosterone’s primary function is to promote sodium and water retention, and potassium excretion; aldosterone antagonists act as potassium-sparing diuretics. However, their effect in heart failure treatment is also attributed to the inhibition of aldosterone’s damaging impact on the heart and blood vessels.
- Digoxin increases cardiac contractility by inhibiting the sodium-potassium pump, causing intracellular sodium concentration to rise. This then leads to higher levels of intracellular calcium via the action of sodium-calcium exchanger. Higher calcium results in increased muscle contraction. Digoxin also decreases sympathetic activities, slowing down heart rate.
- Ivabradine slows the heart rate by inhibiting the “funny” channel responsible for spontaneous firing of the SA node. Adverse effects include bradycardia, atrial fibrillation, and vision problems.
- ARNIs are a new class of medications. ARNI therapy consists of a neprilysin inhibitor and an ARB.

Digoxin Toxicity - Symptoms, Diagnosis & Treatment | Credihealth Side Effects 3 Views • 5 months ago

Digoxin Toxicity - Symptoms, Diagnosis & Treatment | Credihealth

Digoxin toxicity is a potentially serious condition that can occur when there are excessive levels of the medication digoxin in the body. Digoxin is a cardiac glycoside primarily used to treat various heart conditions, including heart failure, atrial fibrillation, and other supraventricular tachycardias.

The signs and symptoms of digoxin toxicity may include:

Cardiac effects:
Bradycardia (slow heart rate)
Irregular heartbeats (arrhythmias)
Cardiac conduction disturbances
Gastrointestinal effects:
Nausea and vomiting
Abdominal pain
Diarrhea
Anorexia

Neurological effects:
Visual disturbances (blurred vision, yellow-green halos)
Confusion
Drowsiness
Headache
Dizziness
Weakness

Other effects:
Electrolyte imbalances (hypokalemia, hypercalcemia)
Increased risk of digoxin toxicity in patients with kidney dysfunction
The risk of digoxin toxicity increases with factors such as:

Excessive dosage of digoxin
Impaired kidney function (reduced clearance of digoxin)
Electrolyte imbalances (hypokalemia, hypercalcemia, hypomagnesemia)
Drug interactions (e.g., with diuretics, antiarrhythmics, antibiotics)
Advanced age
Low lean body mass

If digoxin toxicity is suspected, immediate medical attention is required. Treatment may involve discontinuing digoxin, administering digoxin-specific antibody fragments (Digibind) to bind and remove digoxin from the body, correcting electrolyte imbalances, and providing supportive care as needed.

Monitoring digoxin levels, adjusting dosages based on kidney function, and avoiding drug interactions are essential measures to prevent digoxin toxicity in patients receiving this medication.

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Digoxin: Use & Effects in Heart Failure (Part 1) | Sketchy Side Effects 3 Views • 5 months ago

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An overview of digoxin, a cardiac glycoside used for symptomatic treatment of chronic heart failure. It explains how digoxin works, the drug's role as an antiarrhythmic and its potential side effects, such as hyperkalemia and gastrointestinal symptoms.

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Digitalis | Digoxin Clinical Uses and Adverse Effects Side Effects 3 Views • 5 months ago

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Digitalis | Digoxin Clinical Uses and Adverse Effects

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Digoxin is used to treat heart failure and abnormal heart rhythms (arrhythmias). It helps the heart work better and it helps control your heart rate.
Digoxin is a medication used to manage and treat heart failure and certain arrhythmias, and abortion. It is in the cardiac glycoside class of drugs. This article outlines the indications, action, and contraindications for digoxin as a valuable agent in managing heart failure and certain arrhythmias
Digoxin is used to treat heart failure, usually along with other medications. It is also used to treat certain types of irregular heartbeat (such as chronic atrial fibrillation). Treating heart failure may help maintain your ability to walk and exercise and may improve the strength of your heart. Treating an irregular heartbeat can also improve your ability to exercise.Digoxin belongs to a class of medications called cardiac glycosides. It works by affecting certain minerals (sodium and potassium) inside heart cells. This reduces strain on the heart and helps it maintain a normal, steady, and strong heartbeat.

How to use Digoxin
Take this medication by mouth with or without food as directed by your doctor, usually once daily. If you are using the liquid form of this medication, carefully measure the dose using the dropper provided by the manufacturer. Do not use a household spoon because you may not get the correct dose.

Your body may not absorb this drug as well if you also eat foods that are high in fiber or if you take certain medications. Take this medication at least 2 hours before or after eating food products that are high in fiber (such as bran). If you are also taking cholestyramine, colestipol, or psyllium, wait at least 2 hours after taking your digoxin dose before taking any of these products. If you are taking antacids, kaolin-pectin, milk of magnesia, metoclopramide, sulfasalazine, or aminosalicylic acid, take them as far apart from your digoxin dose as possible. Ask your pharmacist if you are not sure when to take any of your medications.

The dosage of this medication is based on your medical condition, age, body weight, laboratory tests, and response to treatment.

Use this medication regularly to get the most benefit from it. To help you remember, use it at the same time each day. Do not stop taking this medication without consulting your doctor. Some conditions may become worse when the drug is suddenly stopped.
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Digoxin SIDE EFFECTS you need to know NOW! Side Effects 3 Views • 5 months ago

DIGOXIN SIDE EFFECTS
Digoxin is derived from foxglove (a flowering plant of the plant genus digitalis). According to the National Capital Poison Center, “all parts of the plant are poisonous, possibly even deadly, if swallowed.”

MECHANISM OF ACTION
Fundamentally, digoxin is a poison. It exerts its therapeutic effect by poisoning a cell membrane protein known as the sodium-potassium ATPase (Na+/K+ pump). When this pump is poisoned, sodium accumulates within the cell (the therapeutic target being cardiac muscle cells). Another cell membrane protein called the sodium-calcium exchanger normally exchanges intracellular calcium for extracellular sodium. However, when the concentration of sodium inside the cell is high (as is the case for someone taking digoxin), the sodium-calcium exchanger shuts down. The consequence? Calcium accumulates within the cardiac muscle cell, which causes the heart to contract more forcefully. This can be useful for patients with heart failure.

Digoxin also stimulates the vagus nerve, which has the effect of slowing the conduction of electrical impulses. For this reason, digoxin can also be used to treat atrial fibrillation.

SIDE EFFECTS
The probability that an individual will experience side effects from digoxin is roughly 1 in 5 (20%). Side effects tend to affect one of three systems: #1 cardiac conduction system (e.g., bradycardia, tachycardia, atrioventricular (AV) block, ventricular arrhythmia); #2 central nervous system (e.g., headache, weakness, dizziness, apathy, confusion, depression, anxiety, delirium, hallucinations); #3 gastrointestinal system (e.g., diarrhea, nausea/vomiting, abdominal pain, intestinal ischemia, intestinal hemorrhagic necrosis).

DIGOXIN TOXICITY
Digoxin is a “narrow therapeutic index drug,” meaning that the difference between a dose that will result in therapeutic failure and a dose that will cause life-threatening toxicity is very small. Somewhere in the middle (a very narrow window) is the therapeutic window. That’s what doctors are aiming for, and the thing is… it is slightly different in every patient. So, the doctor will consider the clinical response of the patient in conjunction with the serum concentration of digoxin to optimize the dose and avoid overt toxicity.

“Digoxin toxicity” is a condition characterized by nausea/vomiting, cardiovascular symptoms (e.g., cardiac arrhythmias), yellow-green visual color disturbances/halo effect, dizziness, and fatigue (Cummings et al.). The symptoms can vary from one patient to another. For instance, many elderly patients exhibit vague symptoms such as dizziness and fatigue, making the diagnosis more difficult. If toxicity is suspected, the physician will order a blood test to check the serum digoxin level. Digoxin toxicity is most likely to occur when the serum digoxin concentration exceeds 2.0 ng/mL.

DIGOXIN TOXICITY TREATMENTS
If digoxin toxicity does occur, treatment do exist. For instance, in the case of a large overdose, an antidote can be given (digoxin immune Fab), which is 80-90% effective in reversing digoxin toxicity. Despite the availability of this and other treatments, digoxin toxicity is a very serious condition. Consider the following quote: “When treated promptly, the outcomes are good, but any delay in treatment can lead to death” (Cummings et al.).

PROBABILITY OF DIGOXIN TOXICITY: 1-4%
In any given patient taking digoxin, the risk of digoxin toxicity is somewhere between 1 in 100 (1%) and 1 in 25 (4%). The risk rises with age. For instance, in those age greater than 40, the risk of toxicity is 1%; however, in those age greater than 85, the risk is closer to 4% (David et al.).

00:00 Introduction
00:18 Narrow therapeutic index
00:47 Theapeutic effects
01:03 Probability of side effects
01:29 Side effects
03:15 Digoxin toxicity
03:41 Digoxin toxicity: symptoms
04:35 Starry Night by Vincent Van Gogh
05:15 Digoxin toxicity: predisposing factors
06:13 Digoxin toxicity: risk by age
06:29 Digoxin toxicity: treatment
07:15 Digoxin drug interactions
08:10 Prevent arrhythmias after ablation

DISCLAIMER
These videos have not been peer-reviewed. This content should not be used as medical advice, and must never replace the professional judgement of a licensed physician. All content on this channel is for educational purposes only.

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Diflucan 150mg 1 capsule | diflucan 150 mg fluconazole | diflucan for fungal & Yeast infection | Side Effects 3 Views • 5 months ago

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Today video is related to antifungal medicine which is used in wide condtions. The medicine name is Diflucan which contains active ingredient Flucanaol. diflucan comes in 50mg and 150 mg capsule. the complete script of video is as follows

Today our video is regarding an oral medicine which is used to treat fungal infection. There are antifungal creams availaible in the market for fungal infection, but some time, creams are not effective so you have to take tablets in order to eliminate the infection
The medicine which we are talking about is Fluconazole, which comes under the brand name of diflucan, which is used to prevent and treat a variety of fungal and yeast infections. It belongs to a class of drugs called azole antifungals. It works by stopping the growth of certain types of fungus.

Fluconazole is used to treat many fungal infections caused by candida including:

Vaginal yeast infections caused by Candida, skin irritation on the head of the penis (balanitis), and fungal infection of the mouth (oral thrush)
infections in your blood or elsewhere in your body
Fluconazole is also used to treat a brain infection called cryptococcal meningitis. This is caused by a fungus called cryptococcus.
urinary tract infection caused by Candida

Lets see the dosage form for Fluconazole .

Fluconazole is available as capsules or a liquid .
for adults Fluconazole comes in 50mg, 150mg or 200mg. the doctor will prescribe you daily or on weekly basis based on your medical condition.
The liquid usually comes in 2 different strengths:

50mg fluconazole in a 5ml spoonful (50mg/5ml)
200mg fluconazole in a 5ml spoonful (200mg/5ml)

The dose for different condtion is given in chart, which dr will prescribed you after seeing your condtion.

oral (mouth) thrush – 50mg a day, taken for 7 to 14 days
vaginal thrush or balanitis – 150mg, taken as a single dose
vaginal thrush that keeps coming back – 150mg, taken once every 72 hours for the first 3 doses, then take 150mg once a week for 6 months
candida infections (in your blood or elsewhere in your body) – 200mg to 800mg a day for several weeks
cryptococcal meningitis – 200mg to 800mg a day for several weeks
to stop cryptococcal meningitis coming back – 200mg a day, taken long term
to prevent fungal infections if you have a weakened immune system (a low white blood cell count) – 50mg to 400mg a day, until your white blood cell count improves

side effects usually include nausea, diarrhea.

Also remember Fluconazole is usually not recommended in pregnancy

#Diflucan
#flucanazol
#antifungal

SYNTHESIS OF DICYCLOMINE | MEDICINAL CHEMISTRY | GPAT-2020 | B.PHARM-4TH SEM Side Effects 3 Views • 5 months ago

📖 Topic Covered in this video:
✔️SYNTHESIS OF DICYCLOMINE
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💊 𝙂𝘿𝘾 (𝙂𝙋𝘼𝙏 𝘿𝙄𝙎𝘾𝙐𝙎𝙎𝙄𝙊𝙉 𝘾𝙀𝙉𝙏𝙀𝙍) 𝙎𝙊𝘾𝙄𝘼𝙇 𝙈𝙀𝘿𝙄𝘼 -
🌐𝙏𝙚𝙡𝙚𝙜𝙧𝙖𝙢:https://t.me/gdc4gpat
🌐𝙞𝙣𝙨𝙝𝙩𝙖𝙜𝙧𝙖𝙢:https://www.instagram.com/gpat_discussion_center/
🌐𝙮𝙤𝙪 𝙩𝙪𝙗𝙚 :https://www.youtube.com/c/GPATDISCUSSIONCENTER
🌐𝙏𝙬𝙞𝙩𝙩𝙚𝙧:https://twitter.com/GPAT_Discussion
🌐𝙁𝙖𝙘𝙚𝙗𝙤𝙤𝙠:https://www.facebook.com/GPATDISCUSSION/
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Free Batch Codes for GDC Classes App :-
Weekly Test - gdcquiz
Pharmacist - pharmacist
Drug Inspector - gdcdi
Pharma Helping Hands - help21
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