Clobex Spray Lotion Shampoo Which one do I use Key PointsClobex Spray and Clobex Shampoo are both topical corticosteroid medicines used to treat psoriasisClobex Lotion is also approved to treat psoriasis as well as the swelling and itching due to other skin conditions such as eczemaClobex topical treatments are used only in patients years of age or olderClobex clobetasol propionate is a superhigh potent topical corticosteroid available as a prescription spray lotion and shampoo Clobex Spray is used to treat plaque psoriasis on the skin and Clobex Shampoo treats scalp psoriasis Clobex Lotion is approved to treat the swelling and itching due to certain skin conditions such as atopic dermatitis eczema and plaque psoriasisLotions and sprays are often more acceptable for use on the skin and hardtoreach areas while shampoos work well on the scalpHow do I use ClobexAlways follow your doctors directions for dosing and length of time to treat your skin or scalp condition Do not exceed the prescribed dose as it may increase the risk for severe side effects Read the patient medication guide each time you get a prescription If you have questions ask your doctor or pharmacistClobex Spray is approved to treat moderate to severe plaque psoriasis affecting up to of your body surface area BSAThe total dosage should not exceed g mL or fl oz per week Do not use more than sprays per application or sprays per dayTreatment should be limited to consecutive weeks Use Clobex Spray for the shortest amount of time needed to clear your skin conditionDo not use Clobex Spray on the face axillae underarm area or groin area or if there is atrophy skin thinning at the treatment site Do not use Clobex Spray to treat rosacea or perioral dermatitisClobex Lotion is used for certain skin conditions such as atopic dermatitis and psoriasis known as corticosteroidresponsive dermatosesYou should not apply more than mL fluid ounces of Clobex Lotion to your skin per weekClobex Lotion should not be used for more than weeks in a row unless your doctor tells you to use it for a longer time Clobex Lotion should only be used for the shortest amount of time needed to treat your skin conditionDo not use Clobex Lotion on the face axillae underarm area or groin area or if there is atrophy skin thinning at the treatment site Do not use Clobex Spray to treat rosacea or perioral dermatitisClobex Shampoo is used to treat moderate to severe forms of scalp psoriasisYou should not apply more than mL fluid ounces of Clobex Shampoo to your scalp per weekDo not use Clobex Shampoo for longer than weeks unless directed by your doctor Clobex Shampoo should only be used for the shortest period of time needed to treat your scalp psoriasisClobex Shampoo should not be used on your face groin or axillae underarms Do not get the medicine into your eyes or on your lips In case of contact rinse thoroughly with water all parts of the body that came in contact with the shampooRelated questions Does Clobex help hair growth How often can I use Clobex Does clobetasol cause hair loss or growth Bottom LineClobex Spray is used to treat psoriasis on the skin and Clobex Shampoo treats scalp psoriasis Clobex Lotion is also approved to treat psoriasis in addition to other skin conditions such as eczema Clobex topical treatments are used only in patients years of age or olderAlways follow your doctors directions for dosing and length of time to treat your skin or scalp condition Do not exceed the prescribed dose as it may increase the risk for severe side effectsThis is not all the information you need to know about Clobex clobetasol propionate Topical Spray lotion or shampoo for safe and effective use Review the full Clobex information and discuss this information and any questions you have with your doctor or other health care provider

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Clobetasol Propionate for Hair Growth: Fact or Fiction? • Discover the truth about clobetasol propionate and its potential for hair growth in this captivating video. Join us as we delve into the science behind this topical corticosteroid, its intended use for skin conditions, and the limited scenarios where it may be considered for hair loss. Learn about the risks and side effects associated with clobetasol propionate and why it's crucial to seek medical guidance. Don't miss out on this informative discussion that separates fact from fiction!

00:00 • Can clobetasol propionate be used for hair growth?
00:20 • What is Clobetasol Propionate?
00:41 • Can Clobetasol Propionate be used for Hair Growth?
01:30 • What are the Risks and Side Effects?

This video explains some common side effects of lumateperone capsules.

@ProfessorTushar

Got bumped up to 15 mg of Camzyos in March. Hear about how I'm doing! Feel free to reach out to me for questions, comments, or concerns.

Part 7 of my Camzyos journey. I was bumped up from 5 mg to 10 mg, and then to 15 mg. Let's hope it does the trick! Any other diabetic or PA Dutch families out there? How has HCM affected you? Let me know!

0:10 Welcome!
1:35 Diabetes and HCM
1:59 Affected Populations
2:56 Taking my Dose (Almost Dying)
4:22 Shoutouts (and Suggestions for BMS)

Mavacameten is a medication used in the treatment of hypertrophic cardiomyopathy. This video explains what it is and how it works, and some of the common side-effects you need to be aware of.

Mavacamten, marketed under the brand name Camzyos, is a medication specifically approved for the treatment of hypertrophic cardiomyopathy (HCM), particularly obstructive HCM. This is a genetic condition characterized by the thickening of the heart muscle, which can lead to obstruction of blood flow and various symptoms such as shortness of breath, chest pain, and fatigue.

How Mavacamten Works
Mavacamten is a first-in-class cardiac myosin inhibitor.

Targeting Myosin: Myosin is a motor protein in heart muscle cells responsible for contraction. In HCM, there is an excessive interaction between myosin and actin (another protein), leading to hypercontractility and thickening of the heart muscle.

Mechanism of Action: Mavacamten works by selectively inhibiting cardiac myosin. This reduces the excessive contractility of the heart muscle, helps relax the muscle, and reduces the obstruction in the left ventricular outflow tract (LVOT). As a result, blood flow from the heart is improved, and symptoms are alleviated.

Indication and Use
Mavacamten is approved for the treatment of symptomatic obstructive hypertrophic cardiomyopathy in adults.

Symptomatic Obstructive HCM: This form of HCM involves a thickened heart muscle that obstructs blood flow out of the heart, leading to symptoms like shortness of breath, chest pain, and fainting. Mavacamten is particularly beneficial for patients who remain symptomatic despite other treatments, such as beta-blockers or calcium channel blockers.

Benefits
Mavacamten offers several important benefits for patients with obstructive HCM:

Reduction in Symptoms: Clinical trials have shown that mavacamten significantly reduces symptoms associated with obstructive HCM, such as shortness of breath, chest pain, and exercise intolerance.

Improved Exercise Capacity: Patients treated with mavacamten have demonstrated improved exercise capacity, as measured by cardiopulmonary exercise testing (CPET). This improvement in exercise tolerance is a significant benefit for patients with HCM, who often experience limitations in physical activity.

Reduction in LVOT Gradient: Mavacamten effectively reduces the LVOT gradient, which is the pressure difference caused by the obstruction in blood flow. Lowering this gradient helps to alleviate symptoms and improve heart function.

Potential to Avoid Surgery: For some patients, mavacamten may reduce the need for invasive procedures, such as septal myectomy (surgical removal of part of the thickened heart muscle) or alcohol septal ablation.

Side Effects
While mavacamten is generally well-tolerated, it can cause side effects, particularly related to its impact on heart function:

Heart Failure: Because mavacamten reduces heart contractility, there is a risk of heart failure if the dose is too high. This necessitates careful monitoring of heart function, particularly ejection fraction (a measure of how well the heart is pumping blood).

Arrhythmias: There is a potential risk for arrhythmias (irregular heartbeats), which also requires monitoring.

Other Side Effects: Some patients may experience symptoms like dizziness, fainting, and fatigue.

Drug Interactions: Mavacamten can interact with other medications, especially those metabolized by the liver enzyme CYP2C19. This necessitates caution when prescribing mavacamten alongside other drugs.

Human Impact
Hypertrophic cardiomyopathy is a condition that can significantly impact a person's quality of life, leading to symptoms that interfere with daily activities and increase the risk of serious complications, including sudden cardiac death. Traditional treatments focus on managing symptoms and reducing the risk of complications, but they do not directly address the underlying hypercontractility of the heart muscle.

Mavacamten (Camzyos) represents a groundbreaking treatment for obstructive HCM because it directly targets the excessive contractility of the heart muscle, offering a novel mechanism of action compared to traditional therapies. For patients with symptomatic obstructive HCM, mavacamten provides a new option that can reduce symptoms, improve quality of life, and potentially decrease the need for surgical interventions.

The development of mavacamten is a significant milestone in the management of hypertrophic cardiomyopathy, providing hope for improved outcomes in a condition that has been difficult to manage with existing therapies. By addressing the root cause of the obstruction, mavacamten offers a targeted and effective treatment that can help patients with HCM live more active and comfortable lives.

Camzyos is a prescription medicine used to treat adults with symptomatic obstructive hypertrophic cardiomyopathy (HCM).
Camzyos may improve your symptoms and your ability to be active.

Video Content:
0:00 Camzyos capsules
0:17 How to use
1:04 Contraindications
1:32 Warnings
2:20 Side effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Camzyos #hcm #medicine

On January 22, 2021, the Food and Drug Administration approved the combination of nivolumab (Opdivo, Bristol-Myers Squibb Co.) and cabozantinib (Cabometyx, Exelixis) as first-line treatment for patients with advanced renal cell carcinoma (RCC).

Efficacy was evaluated in CHECKMATE-9ER (NCT03141177), a randomized, open-label trial in patients with previously untreated advanced RCC. Patients were randomized to receive either nivolumab 240 mg over 30 minutes every 2 weeks in combination with cabozantinib 40 mg orally once daily (n=323) or sunitinib 50 mg orally daily for the first 4 weeks of a 6-week cycle (4 weeks on treatment followed by 2 weeks off) (n=328).

The trial demonstrated a statistically significant improvement in progression-free survival (PFS), overall survival (OS) and confirmed overall response rate (ORR) for patients treated with nivolumab plus cabozantinib compared with those who received sunitinib. Median PFS per blinded independent central review (BICR) was 16.6 months versus 8.3 months; HR 0.51 (95% CI: 0.41, 0.64). Median OS was not reached in either arm; HR 0.60 (95% CI: 0.40, 0.89). Confirmed ORR per BICR was 55.7% and 27.1% in the nivolumab plus cabozantinib and sunitinib arms, respectively.

The most common adverse reactions (= 20%) in patients receiving the combination of nivolumab and cabozantinib were diarrhea, fatigue, hepatotoxicity, palmar-plantar erythrodysaesthesia syndrome, stomatitis, rash, hypertension, hypothyroidism, musculoskeletal pain, decreased appetite, nausea, dysgeusia, abdominal pain, cough, and upper respiratory tract infection.

The recommended dose is nivolumab 240 mg every 2 weeks (30-minute intravenous infusion) or 480 mg every 4 weeks (30-minute intravenous infusion) in combination with cabozantinib 40 mg orally once daily without food until disease progression or unacceptable toxicity.

View full prescribing information for Opdivo.
View full prescribing information for Cabometyx.

The nivolumab review used the Real-Time Oncology Review (RTOR) pilot program, which streamlined data submission prior to the filing of the entire clinical application. Both the nivolumab and the cabozantinib applications used the Assessment Aid, a voluntary submission from the applicant to facilitate the FDA’s assessment. The FDA approved this application approximately one month ahead of the FDA goal date.

The nivolumab application was granted fast track review, and both the nivolumab and cabozantinib applications were granted priority review. A description of FDA expedited programs is in the Guidance for Industry: Expedited Programs for Serious Conditions-Drugs and Biologics.

Healthcare professionals should report all serious adverse events suspected to be associated with the use of any medicine and device to FDA’s MedWatch Reporting System or by calling 1-800-FDA-1088.

Sumanta Kumar Pal, MD of City of Hope , Duarte, CA shares the new research in renal cell carcinoma he is most excited about at the European Society for Molecular Oncology (ESMO) 2016 Congress in Copenhagen, Denmark. He discusses data he is presenting at this congress on quality of life in the context of cabozantinib treatment (NCT01865747). Dr Pal describes the step-wise increase in quality of life seen during the course of therapy with this second-line agent in renal cell carcinoma, and argues why he prefers cabozantinib over other treatment options.

Dr. Rupeena Purewal invites special guest Saskatoon pharmacist Carley Pozniak to review Cabenuva, an antiretroviral agent for HIV. Cabenuva (Cabotegravir Extended Release Injectable Suspension) has been approved in 2020 for medical use in Canada.

Cabenuva is a long-acting injectable treatment for HIV-1, combining cabotegravir and rilpivirine. It is administered monthly or every two months and helps maintain viral suppression in people living with HIV.

Today I started Cabenuva, which is an injectable HIV treatment option. Every four weeks, I will go to the clinic to get the cabenuva injections. Although there is no cure for HIV, the ability to no longer have to take pills is hugely relieving.

Nebivolol is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems.This medication belongs to a class of drugs known as beta blockers. It works by blocking the action of certain natural substances in your body, such as epinephrine, on the heart and blood vessels. This effect lowers heart rate, blood pressure, and strain on the heart.

Nebivolol, also known as Bystolic, is a medication used to treat high blood pressure. By lowering high blood pressure, it helps prevent strokes, heart attacks, and kidney problems. This medication belongs to a class of drugs called beta blockers, and it works by blocking the action of certain natural substances in the body, such as epinephrine, on the heart and blood vessels. This lowers heart rate, blood pressure, and strain on the heart. It is important to take Bystolic exactly as prescribed by your doctor, and the typical starting dose is 5 mg once daily. It can be taken with or without food, but it is important to take it at the same time each day. Always follow your doctor's instructions for the best results.
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There are clinics all around the state where opioid addicts are getting help, reports Bill Hudson.
WCCO 4 News At 5 – May 4, 2016

There are a growing number of investigations of novel combination therapies for chronic lymphocytic leukemia (CLL). These are discussed in this interview with Peter Hillmen, MBChB, PhD, FRCP, FRCPath, from Leeds Teaching Hospital NHS Trust, Leeds, UK, which took place at the American Society of Oncology (ASCO) 2018 Annual Meeting, held in Chicago, IL. Prof. Hillmen provides an insight into the novel agents currently in trials, as well as the pros and cons of ibrutinib, and how it stacks up against a next-generation BTK inhibitor combination that is more specific, tolerable and has shown fewer side effects for CLL patients.

Este es uno de los videos que ofrece información creíble, gratuita e integral sobre prevención y detección de enfermedades, diagnóstico, tratamiento e investigación. Nuestros videos contienen información de expertos y personas reales sobre diversos problemas de salud, respondiendo la mayoría de sus preguntas, incluyendo cómo sucedió, cómo se siente, qué puede hacer al respecto y por qué es importante

Learn how to use Dry Powder Inhaler (DPI) and Metered Dose Inhaler (MDI) for inhalation of steroids (Budesonide) in mild Covid-19

Breo Ellipta combines an inhaled steroid with a long acting compound that dilates the airways. Marketed for both asthma and chronic obstructive pulmonary disease or COPD, it often fails to provide an ideal treatment for either. For most asthmatics preferred therapy includes inhaled steroids and short acting bronchodilators. The FDA recently linked long acting bronchodilators with increased hospitalization and death related to asthma. Optimal therapy for most individuals with COPD includes a long acting bronchodilator and a long acting anti-cholinergic but not an inhaled steroid. Breo often seems misused by patient and doctor alike.

What is Breo Ellipta inhaler used for?

BREO ELLIPTA is used to treat asthma and chronic obstructive pulmonary disease (COPD). To use BREO ELLIPTA, you breathe it into your lungs through your mouth using the ELLIPTA inhaler.
Asthma is when the muscles surrounding the smaller airways become tight (bronchoconstriction), swollen and irritated (inflammation). Symptoms come and go and include shortness of breath, wheezing, chest tightness and cough.

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Ibandronate is a medication used to prevent and treat certain types of bone loss, known as osteoporosis. Osteoporosis causes bones to become thinner and break more easily, especially after menopause, as you age, or if you take corticosteroid medications for long periods. This medication works by slowing down bone loss to help maintain strong bones and reduce the risk of broken bones. Ibandronate belongs to a class of medications called bisphosphonates.
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FOSIMAX, BONIVA, ACTONEL

Boniva: Side Effects, Dosage & Uses


the Drugs is a chennel where we explain everything about drugs and side effects of drugs ans the using of it and also the doses.

Ibandronate is an amine containing bisphosphonate indicated for the treatment of osteoporosis in postmenopausal women.

Ibandronate, also known as Boniva, is a medication used to prevent and treat certain types of bone loss, specifically osteoporosis. Osteoporosis causes bones to become thinner and more prone to breaking, which can increase the risk of fractures. This medication works by slowing down the loss of bone density, helping to maintain strong bones and reduce the risk of fractures. It belongs to a class of medications called bisphosphonates. It is commonly prescribed to postmenopausal women, elderly individuals, and those who have been taking corticosteroid medications for long periods. The recommended daily dosage is typically taken on a monthly basis, and it's important to take this medication at the same time each month on an empty stomach with a full glass of water.
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Indulge in the knowledge of Pepto’s power to treat digestive symptoms due to overindulgence.

Hi Friends Welcome To Gyanear The Medical Channel I'm Shivam A Registered Pharmacist

Biclutamide Uses, Mode Of Action, Dose & Side Effects In Hindi

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Because these medicines can harm you
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Prostate cancer specialist, Dr. Sartor says the study in the New England Journal of Medicine followed men with low-grade prostate cancer.

Synagis, also known as Palivizumab, is a monoclonal antibody medication that is used to prevent severe RSV infections in infants and young children. RSV is a common respiratory virus that can cause mild cold-like symptoms in most people. However, in premature infants and children with certain medical conditions, RSV infections can lead to serious complications such as pneumonia and bronchiolitis.

Synagis works by targeting the RSV virus and preventing it from replicating in the body. It is administered as a monthly injection during the RSV season, which typically begins in the fall and lasts through the spring. The medication provides temporary protection against RSV, reducing the risk of severe illness and hospitalization.

It is important to note that Synagis is not a vaccine and does not provide long-term immunity against RSV. Each dose of Synagis offers protection for about a month, so it is necessary to receive monthly injections throughout the RSV season to maintain its effectiveness.
Who needs Synagis?.
Synagis is typically prescribed for infants and young children who are considered at high risk of severe RSV infections. This includes premature infants born before 29 weeks of gestation, infants with chronic lung disease or certain heart conditions, and children with certain genetic or immunodeficiency disorders.

The decision to prescribe Synagis is usually made by the child's healthcare provider based on various factors, including the child's gestational age, overall health, and the prevalence of RSV in the local community. It is essential to discuss your child's individual risk factors with your healthcare provider to determine if Synagis is appropriate for them.
Benefits of Synagis.
The primary benefit of Synagis is its ability to reduce the risk of severe RSV infections in vulnerable infants and young children. RSV can be particularly dangerous for premature babies and those with underlying health conditions, as their immune systems are not fully developed or may be compromised. By receiving Synagis, these high-risk individuals have a better chance of avoiding hospitalization and serious complications associated with RSV infections.

Studies have shown that Synagis can significantly decrease the rate of hospitalization due to RSV infections in eligible infants. It is estimated that the medication can reduce the risk of hospitalization by up to 55% in premature infants and up to 45% in children with chronic lung disease. This reduction in hospitalizations not only protects the child from potential harm but also alleviates the burden on healthcare resources.
However, it is important to remember that Synagis is not a guarantee against RSV infections. While it significantly reduces the risk, there is still a possibility for breakthrough RSV infections. Therefore, it is crucial to take additional preventive measures, such as practicing good hand hygiene and avoiding close contact with individuals who are sick, to further protect your child.
Potential side effects of Synagis.
Like any medication, Synagis may come with potential side effects. While these side effects are generally rare, it is important to be aware of them and discuss any concerns with your healthcare provider. The most common side effects reported with Synagis include redness, swelling, or tenderness at the injection site, as well as a mild fever or irritability.

In rare cases, more severe side effects may occur. These can include allergic reactions such as difficulty breathing, rash, or swelling of the face, lips, or tongue. If your child experiences any unusual symptoms after receiving Synagis, it is important to seek medical attention immediately.

It is worth noting that the benefits of Synagis in preventing severe RSV infections generally outweigh the potential risks of side effects. Your healthcare provider will carefully consider your child's individual situation and weigh the benefits and risks before recommending Synagis.

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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.



"

📌 Everything you need to know about RSV protection for babies in Australia (2025 update)

RSV (respiratory syncytial virus) is a super common virus, but for some babies — especially under 6 months — it can cause serious illness like bronchiolitis or pneumonia.

In this video, we walk through the latest RSV protection options now available in Australia, including:
✔️ The RSV vaccine for pregnant women (Abrysvo)
✔️ The long-acting monoclonal antibody for infants (Beyfortus)
✔️ Who is eligible
✔️ How they work
✔️ Common side effects
✔️ What’s different from the vaccine that was discontinued in earlier trials

We’ve kept this video calm, clear, and evidence-based — it’s not about telling you what to do, but simply explaining what’s now available and why.

If this is something you're considering, have a chat with your GP or midwife to explore what’s right for you and your baby.

#RSV #Abrysvo #Beyfortus #PregnancyVaccine #BabyHealth #Australia #RSVvaccine #NewbornCare

Avastin cleaner version

Government advisors say Avastin should not be used to treat breast cancer.