In this segment, panelists discuss the role of bevacizumab in metastatic breast cancer treatment.

ＬＩＫＥ | ＣＯＭＭＥＮＴ | ＳＨＡＲＥ | ＳＵＢＳＣＲＩＢＥ
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✅✅ Avastin ✅ Bevacizumab ✅ ✅ USES || SIDE EFFECTS || DOSAGE || DRUG INTERACTIONS
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✅ #Avastin, #Bevacizumab

Sean Dowdy, M.D., a Mayo Clinic gynecologic oncologist discusses a study showing molecular sequencing could identify ovarian cancer patients who are most likely to benefit from treatment with bevacizumab (Avastin), a Mayo Clinic-led study has found. For more information

Practitioners require an understanding of side effects for commonplace treatment options in colorectal cancer. Karon Martyn, MSN, ANP-BC, AOCNP, discusses bevacizumab/cetuximab and the associated side effects.

📌 Everything you need to know about RSV protection for babies in Australia (2025 update)

RSV (respiratory syncytial virus) is a super common virus, but for some babies — especially under 6 months — it can cause serious illness like bronchiolitis or pneumonia.

In this video, we walk through the latest RSV protection options now available in Australia, including:
✔️ The RSV vaccine for pregnant women (Abrysvo)
✔️ The long-acting monoclonal antibody for infants (Beyfortus)
✔️ Who is eligible
✔️ How they work
✔️ Common side effects
✔️ What’s different from the vaccine that was discontinued in earlier trials

We’ve kept this video calm, clear, and evidence-based — it’s not about telling you what to do, but simply explaining what’s now available and why.

If this is something you're considering, have a chat with your GP or midwife to explore what’s right for you and your baby.

#RSV #Abrysvo #Beyfortus #PregnancyVaccine #BabyHealth #Australia #RSVvaccine #NewbornCare

FDA Approves beyfortus, the first RSV drug to protect all Infants from virus.
While the infection often leads to mild, coldlike symptoms, it is the leading cause of hospitalization of infants in the U.S.

Alex sits down the PCRI's Executive Director, Mark Scholz, MD, to discuss commonly asked questions from the PCRI Helpline on the topics of Casodex (bicalutamide), SpaceOAR, and questions related to pathology (e.g. biopsies, Gleason score).

1:01 Why is Casodex added to everything?

Originally Casodex was added to Lupron (or another hormonal agent) to counteract the testosterone flare that occurs in the first month of hormonal treatment. Additionally, studies showed a slight survival advantage—without significant additional side effects—in men who continued to use the Casodex and the Lupron together for the entire duration of the treatment. However, in the past, Casodex's high cost made it impractical to use for longer than the first month to suppress the Lupron flare.

3:01 Is Casodex Chemotherapy?

While Casodex is often designated at a chemotherapy for billing reasons, it is in a totally different class of medications than chemotherapies like Taxotere and Jevtana.

3:50 What are the side effects of Casodex?

The side effects of Casodex are similar to Lupron, except usually milder; when added to Lupron, some men will experience increased fatigue. In a small number of patients, Casodex can cause liver irritation, and so it is recommended that patients speak with their physician about checking their liver function with a hepatic panel about 4-6 weeks after starting Casodex. When used alone, Casodex can cause breast tenderness and enlargement. This can be counteracted by radiation to the nipples prior to treatment, the use of an aromatase inhibitor, or both.

6:18 What is SpaceOAR?

SpaceOAR is an injectible gel (administered through the perineum) that separates the prostate from the rectal wall to prevent radiation proctitis. Although increasingly rare as technology and practices improve, radiation proctitis can be disastrous if it occurs, and so the use of SpaceOAR is a wise choice.

10:16 Which doctors provide SpaceOAR? How do I find one?

You can find doctors that use SpaceOAR on the SpaceOAR website, or you can ask your radiation oncologist if they are familiar with the technology. If they are not, then that may be a good indication that this physician is not up to speed with the latest developments in the field.

11:37 How do I interpret my biopsy report?

Biopsy reports are given for 12-core random biopsies. Each core ought to be labeled with the location within the prostate from which it was taken. This is not universal, unfortunately, but it is good practice. Physicians are looking for the number of cores that contain cancer cells. If a core has cancer cells, then the biopsy report will say what percentage of the core involved cancer cells. The Gleason score is the final significant component of the biopsy report. Essentially, your doctor wants to know "How big is the tumor?" and "What grade is the tumor?"

15:03 How accurate are biopsy reports? Should I get a second opinion?

There is oftentimes disagreement among pathologists as to the exact grade of a given sample. It's a good idea, then, to get a second opinion on a pathology report. There are many good options. Jonathan Epstein of John Hopkins, for example, has a good reputation and a convenient system for sending in reports for a second opinion.

16:53 What can I do with my Gleason score?

Gleason score, among other factors, determines the best treatment (or non-treatment) for a man to balance achieving a cure (if necessary) and avoiding the side effects of overtreatment.

Who we are:

The Prostate Cancer Research Institute (PCRI) is a 501(c)(3) not-for-profit organization that is dedicated to helping you research your treatment options. We understand that you have many questions, and we can help you find the answers that are specific to your case. All of our resources are designed by a multidisciplinary team of advocates and expert physicians, for patients. We believe that by educating yourself about the disease, you will have more productive interactions with your medical professionals and receive better individualized care. Feel free to explore our website or call our free helpline at 1 (800) 641-7274 with any questions that you have. Our Federal Tax ID # is 95-4617875 and qualifies for maximum charitable gift deductions by individual donors.

The information on the Prostate Cancer Research Institute's YouTube channel is provided with the understanding that the Institute is not engaged in rendering medical advice or recommendation. The information provided in these videos should not replace consultations with qualified health care professionals to meet your individual medical needs.

#ProstateCancer #Prostate #MarkScholzMD

Casodex contains a medicine called bicalutamide.
This belongs to a group of medicines called ‘anti-androgens’.
Casodex is used to treat prostate cancer.

Hi Friends Welcome To Gyanear The Medical Channel I'm Shivam A Registered Pharmacist

Biclutamide Uses, Mode Of Action, Dose & Side Effects In Hindi

🔥🔥Take any medicine only after consulting your doctor
Because these medicines can harm you
Video is only for your information🔥🔥

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Disclaimer:All information is based on the data collected,consult a doctor before using any medication.
Some Contents Are Used For Educational Purpose Under Fair Use. 

Wondering what Pepto Bismol is and how it can help you? In this video, we explain in detail what Pepto Bismol is and its many uses. Discover how this miracle medicine works, its properties and all the benefits it can offer for your digestive health. Additionally, we provide you with clear instructions on how to take Pepto Bismol safely and inform you about possible side effects that you should be aware of. Don't miss this complete guide to understand everything about Pepto Bismol.

#PeptoBismol #DigestiveHealth #HealthTips #Medicine #Health

This video was made by Yvonne Cunningham, 2023 Pharmacist Candidate. She will review: Patient consultation points, indications, dosing and adjustments, mechanism of action, side effects, and monitoring parameters

This video was made by Randy Nguyen , 2023 Pharmacist Candidate. He will review: Patient consultation points, indications, dosing and adjustments, mechanism of action, side effects, and monitoring parameters

Learn how to use Dry Powder Inhaler (DPI) and Metered Dose Inhaler (MDI) for inhalation of steroids (Budesonide) in mild Covid-19

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Este es uno de los videos que ofrece información creíble, gratuita e integral sobre prevención y detección de enfermedades, diagnóstico, tratamiento e investigación. Nuestros videos contienen información de expertos y personas reales sobre diversos problemas de salud, respondiendo la mayoría de sus preguntas, incluyendo cómo sucedió, cómo se siente, qué puede hacer al respecto y por qué es importante

Secrets of the side effects of Breztri Aerosphere
**Common Side Effects (occurring in more than 1% of patients)**

* Upper respiratory tract infections (e.g., sore throat, sinus infection)
* Cough
* Headache
* Diarrhea
* Nausea
* Blurred vision
* Increased heart rate
* Dry mouth
* Throat irritation
* Abdominal pain
* Muscle aches
* Vomiting
* Fatigue
* Rash
* Dry cough

**Less Common Side Effects (occurring in less than 1% of patients)**

* Pneumonia
* Bronchitis
* Wheezing
* Chest tightness
* Shortness of breath
* Anxiety
* Dizziness
* Insomnia
* Taste changes
* Trembling
* Ear pain
* Dry eye

**Serious Side Effects**

* **Pneumonia:** A serious lung infection that can cause fever, chills, cough, and shortness of breath.
* **Bronchitis:** A lung infection that causes inflammation and swelling of the bronchial tubes, leading to cough, wheezing, and shortness of breath.
* **Anaphylaxis:** A severe allergic reaction that can cause difficulty breathing, swelling of the face and throat, hives, and low blood pressure.
* **Increased risk of serious cardiovascular events (e.g., heart attack, stroke):** Breztri contains formoterol, which can increase heart rate and blood pressure.
* **Hyperthyroidism:** This is a condition in which the thyroid gland produces too much thyroid hormone. Symptoms can include weight loss, increased appetite, rapid heart rate, and nervousness.

**Other Possible Side Effects**

* **GlaxoSmithKline has issued a warning about the potential for serious side effects with Breztri Aerosphere.** These include:
* Increased risk of death in patients with severe asthma exacerbations
* Increased risk of serious asthma-related events (e.g., intubation, hospitalization)
* **Breztri Aerosphere should only be used by patients who are 12 years or older.**
* **Patients who are taking Breztri Aerosphere should avoid smoking.** Smoking can worsen asthma symptoms.
* **Patients who are taking Breztri Aerosphere should tell their doctor about any other medications they are taking.** Some medications can interact with Breztri Aerosphere.
* **Patients who are taking Breztri Aerosphere should get regular check-ups with their doctor to monitor their progress.**

How Breztri Aerosphere Works.
Breztri Aerosphere offers a breakthrough solution to the challenges faced in treating asthma and COPD. Its unique formulation combines three active ingredients – budesonide, glycopyrronium, and formoterol fumarate – in a single inhaler device. This triple-combination therapy targets the key components of both diseases, providing comprehensive symptom relief and improving lung function.
Budesonide, a corticosteroid, acts as an anti-inflammatory agent, reducing airway inflammation and preventing exacerbations. Glycopyrronium is an anticholinergic that helps relax the airway muscles, reducing bronchoconstriction and improving airflow. Formoterol fumarate, a long-acting beta-agonist, further enhances bronchodilation and supports long-term symptom control.
The unique formulation of Breztri Aerosphere ensures that each active ingredient is delivered directly to the lungs where it is needed most. The inhaler device utilizes advanced technology to optimize drug deposition and increase lung penetration, maximizing the therapeutic effects of the medication.
Key Benefits of Breztri Aerosphere.
Breztri Aerosphere offers several key benefits that set it apart from traditional asthma and COPD treatments. Firstly, its triple-combination therapy provides a comprehensive approach to managing symptoms, addressing inflammation, bronchoconstriction, and airflow obstruction simultaneously. This holistic approach leads to improved symptom control and better overall disease management.
In addition to symptom relief, Breztri Aerosphere also improves lung function. Clinical studies have shown that patients using the medication experience increased forced expiratory volume in one second (FEV1) – a measure of lung function – compared to those using other asthma and COPD treatments. This improvement in lung function translates to better exercise tolerance and increased overall respiratory health.
Furthermore, Breztri Aerosphere's convenient inhaler device simplifies treatment regimens and enhances patient adherence. The single inhaler design eliminates the need for multiple devices, reducing the risk of confusion and medication errors. Its easy-to-use mechanism allows patients to incorporate the medication seamlessly into their daily routines, ensuring consistent and effective treatment.
Clinical Studies and Efficacy of Breztri Aerosphere.
Clinical studies have demonstrated the efficacy and safety of Breztri Aerosphere in treating both asthma and COPD. In a randomized, double-blind trial involving patients with moderate to severe COPD, Breztri Aerosphere was found to significantly improve lung function and reduce exacerbations compared to other inhaler treatments. The study also showed that the medication was well-tolerated, with a similar safety profile to other commonly used inhalers.
Similarly, studies involving patients with asthma have shown promising results. Breztri Aerosphere was found to effectively control symptoms and improve lung function compared to other asthma treatments. Its triple-combination therapy demonstrated superior efficacy in reducing exacerbations and improving overall disease control.
The positive outcomes observed in these studies highlight the potential of Breztri Aerosphere as a game-changing treatment option for both asthma and COPD patients. Its comprehensive approach and proven efficacy make it a promising choice for healthcare providers and patients seeking optimal symptom control and improved quality of life.
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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.



"

Breztri vs Trelegy Ellipta – Don’t Get Them Mixed Up

Breztri Aerosphere
• Ingredients: Budesonide (ICS) + Glycopyrrolate (LAMA) + Formoterol (LABA)
• Device: Pressurized metered-dose inhaler (pMDI) — shake before use
• Indication: COPD (not FDA-approved for asthma in the U.S.)
• Dose: 2 puffs twice daily

⸻

Trelegy Ellipta
• Ingredients: Fluticasone furoate (ICS) + Umeclidinium (LAMA) + Vilanterol (LABA)
• Device: Dry powder inhaler (DPI) — breath-activated, no shaking
• Indication: COPD and asthma (some strengths for asthma)
• Dose: 1 inhalation once daily

⸻

Key Differences to Prevent Mix-Ups
• Device type: Breztri = MDI (press and inhale), Trelegy = DPI (inhale fast and deep)
• Frequency: Breztri = 2× daily, Trelegy = 1× daily
• Approved use: Trelegy has asthma approval; Breztri doesn’t (in U.S.)
• Appearance: Breztri = canister in inhaler body, Trelegy = flat rectangular device with cover

⸻

⚠️ Why it matters:
📌Mixing them up can cause wrong dosing, under-treatment, or overdosing. Always check the name and directions on your prescription before use.

📌 Gargle 💦 water after both Breztri and Trelegy.

Not medical advice. For educational purposes only.

Your Guide to Breztri Aerosphere for COPD!

Breathe easier with our friendly guide to Breztri Aerosphere for COPD! Learn how it works, tips for proper use, side effects, and important safety info. Comment and share your experience!


00:00 Getting Started
01:26 Medicine Breakdown
03:06 Usage Tips
04:14 Side Effects
05:13 Safety & Risks
07:14 Medical History
08:49 Final Tips


## Getting Started
- Overview: The video introduces COPD and highlights Breztri Aerosphere as a powerful prescription inhaler designed for long-term COPD management.
- Triple Therapy: Emphasizes the unique combination of three medications and explains that Breztri Aerosphere is FDA approved for adults with COPD.

## Medicine Breakdown
- Ingredients Explained: Each of the three components—Budesonide, Glycopyrrolate, and Formoterol Fumarate—is discussed, including their distinct roles in opening airways and reducing inflammation.
- Mechanism & Maintenance: Details how the combination therapy works and stresses that Breztri Aerosphere is a maintenance medication, not for acute symptom relief.

## Usage Tips
- How to Use: Provides step-by-step advice for inhaler use, including dosage instructions and the importance of consistency.
- Rinsing & Rescue: Stresses other practical tips such as rinsing the mouth to prevent thrush and always carrying a rescue inhaler.

## Side Effects
- Common Side Effects: Describes possible mild side effects like respiratory infections, thrush, joint pain, headache, and more.
- Serious Side Effects: Outlines potentially severe reactions, including pneumonia, allergic responses, heart effects, and glaucoma symptoms.

## Safety & Risks
- Health Monitoring: Alerts viewers to watch for signs like increased mucus, fever, or breathing changes, as Breztri may weaken the immune system and affect steroid hormone production.
- Cautions & Contraindications: Warnings for potential risks like adrenal suppression, heart and nervous system concerns, bone thinning, and effects on blood chemistry.

## Medical History
- Disclosure Importance: Encourages discussing full medical history with healthcare providers before starting Breztri Aerosphere.
- Interactions: Highlights crucial medication interactions and stresses the importance of updating medication lists.

## Final Tips
- Pregnancy & Breastfeeding: Advises consulting healthcare providers about Breztri Aerosphere's safety for pregnancy and breastfeeding.
- Specialist Guidance: Underscores the need for regular communication with healthcare professionals and summarizes key recommendations for safe, effective use.

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Aclidinium Oral Inhalation review, aclidinio: What is aclidinium?, what is aclidinium used for, aclidinium uses, aclidinium dosage, aclidinium side effects, aclidinium brand names: Tudorza Pressair, Duaklir Pressair (containing Aclidinium, Formoterol).

What is aclidinium? and What is aclidinium used for?

Aclidinium is used as a long term treatment to prevent wheezing, shortness of breath, coughing, and chest tightness in patients with chronic obstructive pulmonary disease (COPD, a group of diseases that affect the lungs and airways) such as chronic bronchitis (swelling of the air passages that lead to the lungs) and emphysema (damage to air sacs in the lungs).
Aclidinium is in a class of medications called bronchodilators.
It works by relaxing and opening the air passages to the lungs to make breathing easier.


How to use aclidinium?

Aclidinium comes as a dry powder in an inhalation device to inhale by mouth. It is usually inhaled twice a day, once every 12 hours. Inhale aclidinium at around the same times every day.
Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand.
Inhale aclidinium exactly as directed.
Do not inhale more or less of it or inhale it more often than prescribed by your doctor.

Do not use aclidinium to treat a sudden attack of wheezing or shortness of breath.
Your doctor will prescribe a rescue medication to treat sudden attacks of symptoms.
Keep this rescue medication with you at all times in case you have sudden difficulty breathing.

Your condition may worsen over time during your treatment with aclidinium. Do not take extra doses of aclidinium if this happens.
Call your doctor or get emergency medical help if your breathing problems worsen, you need to use your rescue medication to treat sudden attacks more often, or your rescue medication does not relieve your symptoms as well as it did in the past.

Aclidinium can help control your symptoms but does not cure COPD.
You may notice some improvement in your symptoms the first day that you use aclidinium, but it may take longer for you to feel the full benefit of the medication.
Continue to use aclidinium even if you feel well. Do not stop using aclidinium without talking to your doctor.

Before you use your aclidinium inhalation device for the first time, read the manufacturer's directions for use carefully.
Ask your doctor or pharmacist to show you how to use the device and practice using it while he or she watches.

Be careful not to get aclidinium powder in your eyes. If you get the powder in your eyes, you may experience blurred vision and sensitivity to light.

The aclidinium inhalation device does not need to be cleaned. If you want to clean the device, you may wipe the outside of the mouthpiece with a dry tissue or paper towel.
Never use water to clean the device because you might damage the medication.


When to use aclidinium?

Before using aclidinium:

tell your doctor and pharmacist if you are allergic to aclidinium, atropine (Atropen, in Lomotil, in Lonox, in Motofen), any other medications, any of the ingredients in aclidinium inhalation powder, or milk proteins.

tell your doctor and pharmacist what prescription and nonprescription medications, vitamins, nutritional supplements, and herbal products you are taking or plan to take.
Be sure to mention any of the following: antihistamines; atropine (Atropen, in Lomotil, in Lonox, in Motofen); glycopyrrolate (Lonhala Magnair, Seebri, in Bevespi Aerosphere, in Utibron); ipratropium (Atrovent); medications for irritable bowel disease, motion sickness, Parkinson's disease, ulcers, and urinary problems; tiotropium (Spiriva); and umeclidinium (Incruse Ellipta, in Anoro Ellipta, in Trelegy Ellipta).
Your doctor may need to change the doses of your medications or monitor you carefully for side effects.

tell your doctor if you have or have ever had glaucoma (increased pressure in the eye that may cause vision loss), benign prostatic hypertrophy (BPH; enlargement of a male reproductive gland), a bladder condition, or any other condition that makes it difficult for you to empty your bladder completely.

tell your doctor if you are pregnant, plan to become pregnant, or are breast-feeding. If you become pregnant while taking aclidinium, call your doctor.


What should I do if I forget a dose?

Skip the missed dose and continue your regular dosing schedule.
Do not inhale a double dose to make up for a missed one.


What side effects can aclidinium cause?

Aclidinium may cause side effects.
Tell your doctor if any of these symptoms are severe or do not go away:

headache.
runny nose and other cold symptoms.
cough.
diarrhea.

Briumvi injection belongs to a class of medications called monoclonal antibodies.
Active ingredient Ublituximab.

Video Content:
0:00 Briumvi injection
0:43 How to use
1:24 Contraindications
2:03 Warnings
2:40 Briumvi side effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Briumvi #multiplesclerosis #medicine

Three things I like about my MS disease modifying drug, Briumvi

* Only two infusions a year (instead of daily oral
meds or weekly injections)

* I get my infusion at home.

* Few side effects.

Briumvi, a monoclonal antibody for treatment of MS, targets B cells to reduce relapses which cause inflammation and nerve damage in the brain and spinal cord. It helps slow disability progression and reduce relapse frequency in relapsing forms and primary progressive MS.

General information regarding Ublituximab (Briumvi). Content created leveraging AI with the goal of bridging access across communities. Please flag any suggestions or errors in the comment section. Thank you!

In this video, Mazyar Shadman, MD, Fred Hutchinson Cancer Research Center, Seattle, WA, comments on BGB-3111-215, a Phase II trial (NCT04116437) evaluating zanubrutinib in patients with B-cell malignancies who have previously exhibited intolerance to ibrutinib and/or acalabrutinib, which has resulted in discontinuation of treatment. Dr Shadman focuses on patients with chronic lymphocytic leukemia (CLL) and elucidates that based on current data from the trial, most patients do not have recurrence of prior adverse events (AEs) experienced on ibrutinib and/or acalabrutinib when taking zanubrutinib. In those where AEs do reoccur, they are of a lower or equal grade. This interview took place at the biennial International Workshop on Chronic Lymphocytic Leukemia (iwCLL) 2023 meeting, held in Boston, MA.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

Mazyar Shadman, MD, Fred Hutchinson Cancer Research Center, Seattle, WA, shares the results of a trial which investigated the tolerability and efficacy of zanubrutinib in patients with B-cell malignancies who were intolerant to acalabrutinib. Overall, it was shown that zanubrutinib was well tolerated by the patient population, with majority of patients not experiencing the side effects that they experienced with acalabrutinib. This interview took place at the 64th ASH Annual Meeting and Exposition congress in New Orleans, LA.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

The problem is that most pharmacies don't carry it or know about it.