Dangerous Side Effects
Heparin injection |#Heparin_injection_in_hindi | Action | Uses | Dosage | Side-effects|#MedicalUpdate
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In This Video Contains :-
(1) " Heparin" Kya hai ??
(2) "M-Hep inj " Similar Brand's Name
(3) " Heparin" Uses in Details
(4) " Heparin" Common Dosage for Adults
(5) " Heparin" Side effects ( Common & Rare )
(6) " Heparin" Precautions & Warnings
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Mechanisms of action of anticoagulant drugs: Heparin, Low-Molecular-Weight Heparin (LMWH), Warfarin (Vitamin K Antagonist - VKAs), and Direct Oral Anticoagulants (DOAs).
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Anticoagulants are drugs used to reduce blood clotting, or coagulation.
Coagulation is critical for the control of bleeding, which has 4 stages:
- Stage 1: formation of platelet plugs.
- Stage 2: formation of blood clots. Coagulation cascade produces thrombin and fibrin.
- Stage 3: termination of clot formation. Antithrombin binds to thrombin, as well as several other clotting factors, and inhibits their function.
- Stage 4: dissolution of blood clots.
Medications that prevent formation of platelet plugs are antiplatelets. Medications that interfere with the function or synthesis of clotting factors are anticoagulants. Anticoagulants and antiplatelets are the 2 classes of antithrombotic drugs.
Heparin binds to antithrombin and increases its affinity for thrombin and other clotting factors, thereby enhancing antithrombin’s inhibitory effect on coagulation, typically up to thousand-fold.
Low-molecular-weight heparin is produced by chemically splitting heparin into pieces of about one-third of its original size. The smaller size reduces its non-specific binding to plasma proteins and blood components, resulting in fewer side effects, longer half-life, and a more predictable dose-dependent response, so monitoring is not usually required. However, the shorter chain length also reduces its ability to bridge between antithrombin and thrombin, producing a reduced inhibitory effect on thrombin. Its anticoagulation effect relies on inhibition of factor 10a, for which a specific five-saccharide motif is sufficient.
Fondaparinux is a synthetic drug based on this five-saccharide sequence. It has a longer half-life and is associated with less bleeding complication than low-molecular-weight heparin in some studies.
Vitamin K Antagonists, such as warfarin, act by inhibiting the enzyme required for activation of vitamin K. Vitamin K is an essential cofactor for the synthesis of many clotting factors.
Direct oral anticoagulants are a new class of synthetic drugs that includes direct thrombin inhibitors and direct factor 10a inhibitors.
The major adverse effect of all anticoagulants is uncontrolled bleeding. Reversal of anticoagulation: hemodialysis, red blood cells transfusion, platelet transfusion, activated charcoal to prevent absorption of the last dose of an oral anticoagulant. Certain anticoagulants have specific reversal agents that can counteract their effect. Heparin’s action can be reversed with protamine. Vitamin K, given orally or intravenously, can counteract warfarin. There are also specific antidotes for direct oral anticoagulants.
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On our first look at anticoagulants part 1, we looked at coumadin, the most commonly used oral anticoagulant. Now we will look at heparin, a commonly used injectable anticoagulant.
Heparin is a pharmaceutical preparation of the naturally occurring anticoagulant produced by white blood cells in various body tissues, obtained from pig intestines or the lungs of cattle. It is an injectable blood thinner used to treat & prevent the formation of clots and the extension of existing clots within the blood. It does not break down clots that have already formed, but it allows the body’s natural clot lysis mechanisms to work normally to break down clots that have formed.
Check out the first Anti-Coagulant video here: https://www.youtube.com/watch?v=V99LIqYvBL0
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Chlorhexidine (Peridex) is an antiseptic mouthwash that's used to treat gingivitis (gum inflammation) in adults. Your dentist might prescribed it for you after a dental checkup if they think you need it. Typically, you rinse with chlorhexidine (Peridex) by mouth twice daily after you've brushed your teeth. Some common side effects of chlorhexidine (Peridex) include staining of the teeth, changes in taste, and hardening of dental tartar.
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What Are The Side Effects Of Chlorhexidine? Chlorhexidine mouthwash is a popular choice for those looking to maintain oral health, especially for treating gum diseases. In this informative video, we will discuss the various side effects associated with chlorhexidine, providing you with essential information to make an informed choice about your oral care routine.
We will cover common side effects such as tooth staining and changes in taste, as well as potential discomforts like mouth soreness and tongue irritation. Additionally, we’ll touch on the more serious reactions that can occur, including allergic responses that require immediate medical attention. It's important to be aware of these side effects to ensure safe and effective use of chlorhexidine.
For those who are pregnant, breastfeeding, or considering this mouthwash for children, we will highlight the necessary precautions to take. By understanding both the benefits and risks associated with chlorhexidine, you can approach your oral health with confidence.
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Chlorhexidine mouthwash ip 0.2% W/V Everfresh antiseptic and antiplaque mouthwash benefits, usage, dosage, precautions, side effects in hindi
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hexidine mouthwash uses:
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Benzoyl peroxide vs Salicylic acid. I'll break down the differences between popular acne treatments benzoyl peroxide and salicylic acid, their benefits, potential side effects, and tips for incorporating them into your skincare routine. By the end, you'll have a clear understanding of which acne-fighting powerhouse is best for your unique skin needs. #skincarelover #acnetreatment #benzoylperoxide #salicylicacid #dermatologist #blackdoctors #acnetreatment #clearskin #glowup
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Humira | Adalimumab – Uses, Side Effects, Dosage, Warnings
Adalimumab, commonly known by its brand name Humira, is a medication that belongs to a class of drugs called tumor necrosis factor (TNF) inhibitors. It is primarily used to treat various inflammatory and autoimmune conditions, including rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis, Crohn's disease, ulcerative colitis, and plaque psoriasis.
In this video, we'll have a look at the uses and side effects of Humira (Adalimumab).
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In this video, Dr. Berg talks about the Humira alternative. Humira is an anti-inflammatory blockbuster and a top-selling prescription drug.
In the US, 70% of the population is on at least 1 drug. Glucose is highly inflammatory and a potent trigger for inflammation. Insulin is anti-inflammatory but high levels of insulin in the blood are also inflammatory.
Consuming too much glucose, sugar, and carbs will increase insulin and develop into a condition called insulin resistance. Lowering insulin resistance could lower inflammation as well.
Ways to Drop Inflammation:
• Low Carb Diet or Healthy Ketosis
• Intermittent Fasting
Dr. Eric Berg DC Bio:
Dr. Berg, age 56, is a chiropractor who specializes in Healthy Ketosis & Intermittent Fasting. He is the author of the best-selling book The Healthy Keto Plan, and is the Director of Dr. Berg Nutritionals. He no longer practices, but focuses on health education through social media.
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In this video I'm going to share with you a few of the most dangerous humira side effects, what this drug is used for and give you some other options.
Before I get started down below is a link where I'm giving away a free video guide to dietary supplements and alternative medicine!
Humira is mostly used to treat inflammation. This can come in handy when someone has arthritis or another example of it's use is with chrone's disease. This is where there is inflammation in the digestive system.
Inflammation is very bad, that is where the immune system attacks itself, it's the main cause of pain with arthritis, it accelerates the aging process and causes health problems. In fact some health experts feel that without inflammation most diseases would not even exist.
The bad news with humira is the side effects. Some people using the drug develop a fast growing type of cancer. It also can lower your ability to fight off infections and weaken the immune system.
The immune system is something you really don't want weak. It also weakens someone's ability to clot blood. This makes it easier to bleed and bruise. The side effects keep adding up, including liver problems, nervous system problems and heart problems. s and I haven't even talked about the minor side effects like allergic reactions or free radicals.
There are much better options.
You could try an anti-inflammatory diet and this includes lots of food with antioxidants and cutting back on processed meals and fast foods.
Reducing stress, mild exercise, reducing toxins, mercury and pesticides all help.
Next would be omega 3. A supplement is a great choice because you don't get the mercury of toxins from fish. Different brands give different results.
You could also try something known as green lipid mussel power.
When it comes to herbal remedies there are tons like ginger, garlic and turmeric.
Lastly, I highly recommend you view a free report and video guide on alternative medicine and supplements. It simplifies buying herbal medicine, and can be very helpful. To check it out click on the link below this video.
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UPDATED VID: https://youtu.be/8ARIAyqqmh0
Had to reup this update video. Hopefully the audio is better in this one.
I talk about how my experience with adalimumab has changed over the years (esp the past 6 months), side effects, effectiveness, and what my doctor said about continuing humira.
Hope this video is helpful! PLEASE share if you think someone else will benefit from it.
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If you or a loved one are exploring the world of Humira, this video is a vital resource to help you understand what this medication is all about.
Unveiling Humira:
In this video, we demystify Humira, a groundbreaking biologic drug that's transforming the lives of those battling chronic conditions linked to the immune system. Discover the key facts you should be aware of to make informed decisions about your health.
The Mechanism Behind Humira:
Learn how Humira works its magic by targeting TNF (tumor necrosis factor), a critical protein in your body associated with inflammation. Understanding this mechanism is pivotal to grasp how Humira can bring relief to those affected by certain health conditions.
Taking Humira with Confidence:
Are you apprehensive about self-administering Humira? Fear not! We'll guide you through the process and shed light on how it's done, ensuring you can take this step with confidence.
Potential Side Effects:
As with any medication, Humira may have side effects. We'll delve into these, detailing the most common ones such as injection site discomfort, headaches, increased susceptibility to respiratory infections, and occasional nausea or stomach discomfort. Being informed empowers you to navigate your health journey.
Consult Your Healthcare Provider:
Before embarking on the Humira journey, remember that consulting your healthcare provider is non-negotiable. Your doctor's expertise is indispensable in determining whether Humira is the right treatment for your unique condition and providing guidance on its safe usage.
In Conclusion:
Humira is a potent ally in managing chronic conditions, but it's vital to be well-informed and maintain open communication with your healthcare provider. Your well-being is paramount, and we're here to support you every step of the way.
If you found this video helpful and enlightening, be sure to show your appreciation by giving it a thumbs up. Subscribe for more insightful content on healthcare and well-being. Thank you for watching, and may you embark on your health journey with confidence and knowledge. Stay healthy!
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Administración de fármacos biológicos: Adalimumab (Humira)
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Humira: The Most Financially Successful Drug Ever!
Humira has made $200 Billion over the course of its pharmaceutical life. The original Humira patent expired, but the makers of Humira--AbbVie--filed an additional 132 patents and extended its patent-life to 2023.
During that time, AbbVie raised the price of Humira 30 times from $522 per syringe to $2,984 per syringe. It now costs $78,000 per year to treat one patient with Humira.
Consequently, AbbVie rose to be worth $270 Billion and is the 23rd most valuable company on the stock market... $80 Billion larger than the Walt Disney Company.
Express Scripts, Optum and Prime Therapeutics will offer biologic alternatives to Humira in 2023, but CVS Caremark has yet to announce any alternative to the expensive medication.
Humira shows how completely ineffective PBMs are in controlling specialty pharmacy costs.
Alternative solutions include: 1) Travel to Mexico/Canada to buy specialty drugs for less, 2) Hire own specialists (e.g. rheumatologists) who will be better stewards of the employers resources while still following clinical best-practices, 3) Have lawyers try to get plan members that take specialty medications on Disability so that Medicare will cover their medication costs, 4) Legislative Advocacy to counter the Pharma lobbying that allowed for confiscatory pricing of specialty pharmacy medications.
Sources:
https://www.fiercepharma.com/s....pecial-reports/top-1
https://news.bloomberglaw.com/....ip-law/abbvies-humir
https://www.fiercehealthcare.c....om/payers/express-sc
https://www.prnewswire.com/new....s-releases/prime-the
https://www.bloomberg.com/news..../articles/2023-01-06
https://www.biopharmadive.com/....news/humira-abbvie-b
https://clincalc.com/DrugStats/Drugs/Adalimumab
https://endpts.com/house-commi....ttee-uncovers-how-hu
https://www.liberatedstocktrad....er.com/sp-500-compan
https://www.fiercepharma.com/p....harma/humira-rings-u
https://nces.ed.gov/fastfacts/display.asp?id=75
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A review of Humira effectiveness by briefing looking at clinical trial results.
https://www.drugs.com/humira.html
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Hydralazine
Generic Name: hydralazine
Trade Name: Apresoline
Indication: hypertension
Action: arterial vasodilation by unclarified mechanism
Therapeutic Class: anti-hypertensive
Pharmacologic Class: vasodilator
Nursing Considerations
may cause tachycardia, sodium retention, arrhythmias, angina
use caution with MAOIs
monitor blood pressure
instruct patient on how to take blood pressure
This video explains some common side effects of hydralazine tablets.
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Hydralazine is an antihypertensive agent used for the management of essential hypertension or severe hypertension associated with conditions requiring immediate action, heart failure, and pre-eclampsia or eclampsia.
In this video, let’s find found:
What is hydralazine?
What is hydralazine used for?
Contraindication
What are the side effects of taking hydralazine?
How does hydralazine work?
How to use hydralazine?
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#hydralazine #vasodilators #Apresoline
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Tags: he-info, hydralazine, hydralazine uses, hydralazine dosage, hydralazine side effects, hydralazine mechanism, hydralazine indication, hydralazine contraindications, hydralazine mechanism of action, blood vessel dilators, vasodilators, hydralazine 25 mg, hydralazine 50 mg, hydralazine 25 mg tablet, hydralazine pharmacology, hydralazine 10 mg, hydralazine injection, hydralazine administration, high blood pressure, heart failure, angina pectoris, myocardial infarction
How Are Hydralazine Side Effects Managed? In this informative video, we will discuss the management of side effects associated with hydralazine, a medication commonly used to treat high blood pressure, especially in urgent situations. Understanding how medical professionals address these side effects is essential for anyone considering or currently using this medication. We will cover the common side effects that patients may experience, ranging from mild issues like headaches and dizziness to more serious complications that require immediate attention.
You’ll learn about various strategies employed by healthcare providers to manage these side effects effectively, including dose adjustments and combination therapy with other medications. Monitoring for serious symptoms is a critical aspect of treatment that we will highlight, ensuring that patients are aware of what to look for during their course of therapy.
Additionally, we will touch on the importance of patient education in managing these side effects and what steps should be taken if side effects occur. Whether you are a patient, caregiver, or simply interested in hypertension treatments, this video will provide essential information for understanding how hydralazine side effects are managed.
Join us for this detailed discussion, and don't forget to subscribe to our channel for more helpful content on hypertension and related health topics.
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About Us: Welcome to Hypertension Help Hub, your go-to channel for everything related to high blood pressure. Here, we provide clear and concise information on High Blood Pressure Basics, Causes of Hypertension, Symptoms, Blood Pressure Monitoring, and Lifestyle Changes for Hypertension. We cover essential topics such as the DASH Diet, Medications for High Blood Pressure, and effective strategies for managing stress to support heart health. Our goal is to equip you with practical tips for Hypertension Prevention and ways to take control of your well-being. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.
Hello!
Here is a short guide on how to treat hypertension using hydralazine (Apresoline). I highlighted some side effects and how to use points in this video. If you have other questions regarding the medications, please be sure to click the link down below to get recommendations from a healthcare professional;
www.demirxcare.com
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This information should not be used to decide whether or not to take this medicine or any other medicine. Only a personal healthcare provider has the knowledge and training to decide which medicines are right for a specific patient. This information does not endorse any medicine as safe, effective, or approved for treating any patient or health condition. This is only a brief summary of general information about this medicine. It does NOT include all information about the possible uses, directions, warnings, precautions, interactions, adverse effects, or risks that may apply to this medicine. This information is not specific medical advice and does not replace information you receive from the healthcare provider. You must talk with your healthcare provider for complete information about the risks and benefits of using this medicine.
Top MPN specialist John Mascarenhas, MD of Mt. Sinai, talks about the current, major treatments for MPNs, specifically myelofibrosis (MF), polycythemia vera (PV), and essential thrombocythemia (ET), including hydroxyurea and newer drugs like ropeginterferon (Besremi). Dr. Mascarenhas also describes common side effects.
Featuring: John Mascarenhas, Dir., Adult Leukemia Program, Tisch Cancer Institute, Mt. Sinai & Professor, Icahn School of Medicine
Full story & transcript → Updated Soon at www.ThePatientStory.com
The interview has only been edited for clarity.
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Contents Of This Video:
00:00 - intro
00:26 - What are current treatment options?
02:00 - Tell us about hydroxyurea
04:25 - Other common MPN treatments & Side Effects
06:10 - How are these different treatments given?
08:00 - Most promising emerging treatments for MPNs
10:15 - Shift in treating MPNs → combinations?
12:09 - Determining myelofibrosis prognosis
13:43 - Determining real-world benefits of fedratinib when ruxolitinib fails
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#ThePatientStory #myeloma #MPN #Cancerexperts #Oncologists #Cancerstories #doctors #Myelofibrosis #PolycythemiaVera #EssentialThrombocythemia
Hydroxyurea Capsule : Therapeutic Uses, Warning and Precautions, Interactions, Directions for Use, Side Effects and Storage. Find out which brands carry Hydroxyurea Capsule here - https://www.netmeds.com/generics/hydroxyurea-500mg
The "JAK Inhibitors for the Successful Management of Patients with Polycythemia Vera” symposium was recorded at the 2015 US Focus on Myeloproliferative Neoplasms and Myelodysplastic Syndromes Congress held in Alexandria, VA, August 28-29, 2015. This symposium highlights key clinical data and recommendations related to the diagnosis, prognosis and therapy of patients with polycythemia vera and the integration of JAK inhibitors into clinical practice.
In this presentation, Dr. Srdan Verstovsek argues that JAK inhibitors should not be limited to hydroxyurea-resistant or intolerant patients.
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#Hydroxyurea #bloodcancer #sicklecellanemia #hematologist #drkarunakumar
In this Video Dr Karuna Kumar explains about a tablet called Hydroxyurea , it's usage in blood disorders and it's sideeffects.
Dr. Karuna Kumar Consultant Hematologist Hemat Oncologist & Bone Marrow Transplant Physician is a renowned Hematologist located in Hyderabad, India. This Channel is to bring in expert medical advice to maintain a good health and well being. Dr. Karuna Kumar will also address key issues , diseases related to Hematology and how to overcome such difficulties in life through proper medical treatments.
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✅ HYDROXYUREA (HYDREA, DROXIA, MYLOCEL, SIKLOS) reviews: Side effects, dosage (capsules 500 mg)), pregnancy, interactions, uses, contraindications, warnings, precautions, mechanism of action (moa), brand names: Hydrea, Droxia, Mylocel, Siklos and answers to questions like: what is hydroxyurea?, What is Hydroxyurea used for?, How does hydroxyurea work?, Hydroxyurea how to use?, Hydroxyurea for sickle cell?
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More information about active ingredients: https://activeingredients.online/
In this webinar, MPN specialist Dr. Naveen Pemmaraju, discusses strategies for managing symptoms and treatment side effects for people living with essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis (MF). Dr. Pemmaraju also shares advice for communicating with your healthcare team and provides an update on the latest MPN treatment and research.
Dr. Naveen Pemmaraju is Director of the Blastic Plasmacytoid Dendritic Cell Neoplasm (BPDCN) Program in the Department of Leukemia at The University of Texas MD Anderson Cancer Center. Learn more about Dr. Pemmaraju, here: https://faculty.mdanderson.org..../profiles/naveen_pem
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Hydrochlorothiazide is a water pill that helps to lower blood pressure and ease swelling from fluid (edema) caused by many health conditions, such as heart failure and kidney problems. Typically, you take hydrochlorothiazide by mouth once (sometimes twice) daily. Some common side effects of hydrochlorothiazide include dizziness and urinating more often.
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