What Is Phenobarbital? In this informative video, we will discuss Phenobarbital, a medication that has been utilized for many years in the treatment of seizures. As a member of the barbiturate class, Phenobarbital is primarily prescribed to individuals with epilepsy, helping to control and manage their condition. We will cover how this medication works in the brain, its various forms of administration, and its additional uses beyond epilepsy.

Phenobarbital is not only effective in managing seizures but also serves as a sedative and can assist in managing withdrawal symptoms from other drugs. However, it is essential to understand the potential risks and side effects associated with its use, including the possibility of dependence and the impact on pregnant or breastfeeding individuals.

Join us as we provide a comprehensive overview of Phenobarbital, including its benefits, risks, and the importance of medical supervision when using this medication. Don't forget to subscribe to our channel for more informative content related to medicine and drugs.

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About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Benziodiazepines vs barbiturates nursing pharmacology and mental health NCLEX review. Benzodiazepines and barbiturates are drugs that are used as sedatives due to their anxiolytic effects. These medications work by depressing the central nervous system.


In this video, Nurse Sarah highlights the similarities and differences between benzodiazepines ("benzos") and barbiturates ("barbs") for nursing students, nurses, and other healthcare professionals.

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This video talks about Barbiturates | Mechanism of action of Barbiturates | use and side effects of barbiturates


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Study this Barbiturates mnemonic and other NCLEX mnemonics with Pixorize.

Barbiturates are a class of drugs, easily recognizable with their “-barbital” ending, with the most common drug being phenobarbital. Barbiturates are CNS depressants, meaning they slow down brain and neural activity. This makes barbiturates useful in treating seizures and treating insomnia. Side effects of barbiturates include sedation, dependence, and respiratory depression. Barbiturates are not commonly prescribed anymore because of their high abuse potential and the risk of fatal overdose.

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Dr. Steve Wolf: Phenobarbital is one of our oldest anti-seizure medications that have been around. It's indicated for both seizure types. The major problem with it is sedation, sleepiness. That's why the newer medications have a lot less sleepiness and side effects and waking issues.

Patty McGoldrick: Now it still is used a lot of times in infants, children who present with neonatal seizures, and that's one of the first medications that's given to them. It's also used for people who present in status, which is prolonged seizures, and who may be in the emergency room. Not necessarily as the first medication that's used for that, but somewhere down the line.

Dr. Wolf: The problem is in the emergency room, when you use it, it can really knock you out, and put you to sleep. And of course, if you give too much of it, it actually can affect your respiration.

Patty: Now, the other big issue with phenobarbital is that we've been using it for years to control seizures in newborns and in infants. And actually, the latest research has shown it can cause much more cognitive damage than we initially thought. So we're trying not to use that as rapidly as we did in the past. We use some of the newer medications. We try to get children off phenobarbital pretty quickly if they were using it.

Dr. Wolf: There were studies in the 80's showing that it can affect hyperactivity in young children, as well as reading scores and attention scores. So again, this drug can have a lot of potential cerebral side effects. That's why it's nice about some of the newer medications that are out there that might have less cognitive effects. So it's important to discuss with the people taking care of you whether this is the right medication for you, and what are the other choices.

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Generic Name,Drug class, Brande Name
What is PHENOBARBITAL ? , 1:00
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Before taking this medicine (Precautions ), 1:27
How to use , 3:23
Dosage info - 4:33
Miss a dose, 6:34 Overdose ,6:51
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Add this Phenytoin NCLEX mnemonic and other mnemonics with Pixorize to your NCLEX study plan.

Phenytoin is an anticonvulsant drug used to treat seizures. Phenytoin has a narrow therapeutic range of 10-20 mcg/mL. High doses of phenytoin above this cutoff can lead to symptoms of acute toxicity. These symptoms include ataxia, slurred speech, and nystagmus. The provider should be notified immediately if these symptoms are seen. Another expected side effect of phenytoin is gingival hyperplasia, so encourage your patients to practice good oral hygiene and visit the dentist regularly.


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In light of the recent kindergarten drug scandal, the government is focusing on medical institutions and prescriptions of phenobarbital medications to prevent and stop dangerous misuse.

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While phenobarbital has been useful in treating conditions like anxiety; it has become a common drug for abuse and addiction. It’s a fast-acting drug and the effects do not usually last as long as other medications.

This makes people bingeing for more doses to keep its effects or use it with other substances including alcohol. When abused, it can cause several side effects and treatment is only possible in a recovery center.

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A complete description of Phenobarbital Na benefits, dosage form, Indications, antidote effects against Strychnine poisoning, epilepsy accept typical absence seizures, status epilepticus, dose, administration, precautions, contraindications, overdose, toxicity symptoms, side effects, storage condition, mechanism, indications, and ADR's.


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Are you wary of Phentermine side effects on your weight loss journey? In this video, Dr. Carter from Modern Body Clinic delves into how to safely incorporate Phentermine, a popular weight loss medication, into your regimen. Discover the pros and cons, how to avoid common pitfalls, and tips for maximizing its effectiveness through diet and exercise.

Modern Body Clinic offers a comprehensive approach to medical weight loss, blending cutting-edge treatments like Semaglutide and Phentermine with personalized care. Whether you're managing diabetes, obesity, or simply aiming for a healthier lifestyle, our team is dedicated to supporting your weight loss journey with expertise in skincare, skin rejuvenation, and anti-aging.

If you're ready to take the next step, we invite you to visit the Modern Body Clinic website https://modernbodyclinic.com or call (480) 725-4905 for a personalized consultation. Our specialists are eager to help you navigate your options and tailor a plan that's just right for you.

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CHAPTERS:
0:00 - Introduction to Phentermine
0:33 - Phentermine Pros and Cons
1:12 - Common Side Effects of Phentermine
1:55 - Safe Phentermine Usage Guidelines
2:36 - Weight Loss Tips Using Phentermine
3:32 - Phentermine Overview Conclusion

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Want to try phentermine (aka Adipex-P or Acxion or Fastin or Duromine or Lomaria or Panbesy or Terfamex) for weight loss? We'll provide an expert overview of this popular medication, including what to watch for, side effects, and how to use it most effectively.

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0:00 Intro
0:37 What is phentermine
1:11 How does it work?
1:47 Side effects
2:55 Is it addictive?
4:02 Can I drink alcohol on phentermine?
4:49 Can I have caffeine on phentermine?
5:27 Is it effective?
6:27 What to expect
7:24 Summary

****************

Learn more about:

Qsymia, a newer, similar medication to phentermine: https://youtu.be/BOROGeVB8aE

Dr. Brian Yeung, ND: https://brianyeungnd.com/about/

****************

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Qsymia (phentermine / topiramate ER) is a combination medication used to help with weight loss. It's approved for use in people over the age of 12 with obesity or adults with at least one weight-related medical condition.

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Before the GLP-1's like Semaglutide, Retatrutide and tirzepatide, phentermine was the go-to weight loss medication. Phentermine is an old school weight loss medication with some new and interesting research surrounding it. It's been around for over 60 years and has helped people lose weight predominately though appetite suppression. Even though there is a ton of research surrounding phentermine, there is some new research as well. Namely, long term phentermine use. We look at 2 different studies that take a look at off-label phentermine use including some patients who took this medication for 24 months non-stop. The dosing of phentermine is all over the board but one source showed people taking 15mg per day and 30mg per day.

Phentermine, just like all medications, can have side effects. Phentermine side effects include physical and psychological. Phentermine has a number of contraindications so make sure you're working with a qualified medical professional if this is a medication you're interested in.

We also briefly take a look at a combination weight loss therapy - phentermine and topiramate brand name Qsymia.

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Phentermine's side effects can be dangerous. This video explores Phentermine facts, use consequences, and interactions.

🚨 Phentermine Side Effects: Understanding Risks and Precautions

Planning to use Phentermine for weight loss? It's crucial to be aware of potential side effects. This video explores common and atypical side effects, usage guidelines, and interactions to ensure a safe experience.

🔍 Overview of Phentermine:
Phentermine, a controlled stimulant, aids short-term weight loss. Combined with a healthy lifestyle, it helps combat obesity-related risks. However, misuse can lead to dependence and adverse effects, especially in women.

📌 Phentermine Uses:
Integral to weight loss programs, Phentermine tackles obesity-related health issues. It's prescribed alongside exercise, behavior modification, and a calorie-restricted diet. Learn how shedding excess weight mitigates risks like heart disease and diabetes.

🚫 Top 10 Phentermine Side Effects:
Understand potential side effects, including elevated blood pressure, insomnia, dry mouth, dizziness, increased heart rate, gastrointestinal issues, mood swings, headaches, sexual dysfunction, and rare allergic reactions. Discover coping strategies for each.

🔄 Phentermine Interactions:
Discover the importance of tracking all medications. Uncover potential interactions with appetite-suppressant drugs, MAO inhibitors, and substances inducing drowsiness. Learn about high blood pressure drugs, phenothiazines, stimulants, and precautions with caffeinated products.

⚠️ Caution with Medical Tests:
Phentermine can affect test results, notably for Parkinson's disorder. Inform healthcare providers to ensure accurate testing. Explore the impact on brain scans and the importance of disclosing medication use.

❓ Is Phentermine Addictive?
Despite a lower addiction risk, Phentermine can lead to physical and psychological dependence. Recognize signs such as tolerance, abuse potential, withdrawal symptoms, and mental health effects. Regular updates to your doctor are essential.

👩‍⚕️ Professional Guidance:
Follow your doctor's instructions on dosage and duration to minimize addiction risk. Stay vigilant for changes in physical and psychological well-being. Professional assistance may be needed for managing withdrawal symptoms. #PhentermineAwareness #WeightLossJourney #HealthAndWellness

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Phentermine is an FDA-approved appetite suppressant that aides in weight loss and is sometimes prescribed by Options Medical Weight Loss along with other appetite suppressants (https://www.optionsmedicalweig....htloss.com/our-servi

In this video, Dr. Katrina Mattingly, board-certified obesity medicine specialist and Chief Medical Officer at Options Medical Weight Loss, talks about appetite suppressants like Phentermine and how they work to effectively help people limit food intake and overall obesity.

Phentermine is a sympathomimetic amine that has been used since the 1950s with lots of success. Learn more about if it's right for you here: https://www.optionsmedicalweig....htloss.com/get-your-

✅ My #1 Recommended Phentermine Alternative: https://tinyurl.com/phenq-discount

Phentermine turned out to be an absolute nightmare for me.

Although I had some great results in the beginning.

In the long term, it gave me serious health problems.

If you are on the verge of taking it, I would recommend you to avoid it.

There are a lots of safe alternatives to phentermine and right now, I am taking one such pill.

It's name is PhenQ and I have seen nothing but great results with it.

PhenQ helps you lose weight in 2 ways.

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#phentermineweightloss

Adipex-P (phentermine) is an appetite suppressant used in combination with diet and exercise for the short-term treatment of obesity.

What is Adipex-P used for?
How much weight can you lose on Adipex-P?
Is Adipex still used for weight loss?
What is the brand name of Adipex-P?

#Adipex-P #antiobesity #phentermine #weightloss
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Phenylephrine is an alpha-1 adrenergic agonist used in the management of hypotension, generally in the surgical setting associated with the use of anesthetics.

In this video, let’s find found:
What is phenylephrine?
What is phenylephrine used for?
Contraindication
What are the side effects of taking phenylephrine?
How does phenylephrine work?
How to use phenylephrine?

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#phenylephrine #antihistamine #advil
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Tags: he-info, phenylephrine, Advil, phenylephrine uses, phenylephrine dosage, phenylephrine side effects, phenylephrine mechanism, phenylephrine indication, phenylephrine contraindications, phenylephrine mechanism of action, decongestant, nasal congestion, phenylephrine hydrochloride, phenylephrine pharmacology, phenylephrine brompheniramine, phenylephrine drip, phenylephrine decongestant, phenylephrine drug, phenylephrine drops, phenylephrine dose, phenylephrine hcl, phenylephrine hcl 10 mg, phenylephrine nasal spray

It’s a common decongestant ingredient found in hundreds of over-the-counter medications. But now, the FDA’s Nonprescription Drugs Advisory Committee says phenylephrine doesn’t actually get rid of nasal congestion.

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Study this Ephedrine / Phenylephrine NCLEX mnemonic and other mnemonics with Pixorize.

Ephedrine, pseudoephedrine, and phenylephrine are medications that have different effects depending on their route of administration. When given nasally or orally, they can be used to treat congestion. When used as a decongestant, a potential side effect is rebound nasal congestion, so patients should not take these medications for more than 3-5 days and should taper off the drug slowly. When given through an IV, these drugs act systemically as vasopressors, where they constrict the blood vessels to increase blood pressure. Regardless of the route of administration, side effects to look out for include CNS stimulation, which can present as insomnia, restlessness, agitation, or nervousness. These drugs can also cause uncontrolled hypertension, and should not be given concurrently with other drugs that cause hypertension, or to patients who already have high blood pressure and other cardiovascular conditions.

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#Ephedrine #Phenylephrine

What Are The Side Effects Of Phenylephrine? In this informative video, we’ll discuss the side effects associated with phenylephrine, a common medication used to relieve nasal congestion. Understanding the potential reactions to this drug is essential for anyone considering its use for colds, allergies, or sinus issues. We’ll cover both common and serious side effects, including how they may impact your health.

Additionally, we’ll highlight the importance of being aware of drug interactions that can occur with phenylephrine, especially if you are taking other medications. For individuals with pre-existing health conditions, we’ll explain why monitoring is necessary and when to seek medical advice.

By the end of this video, you’ll have a clearer picture of what to expect when using phenylephrine and how to use it safely. This knowledge can help you make informed decisions about your health and medication use. Don’t forget to consult with your healthcare provider if you have any questions or concerns regarding this medication. Join us for this essential discussion, and subscribe to our channel for more useful information on medicine and health topics.

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#Phenylephrine #NasalCongestion #ColdRelief #AllergyRelief #SinusIssues #MedicationSafety #HealthTips #DrugInteractions #SideEffects #Healthcare #PatientSafety #MedicalAdvice #Pharmacy #OverTheCounter #AllergyMedications #HealthAwareness

About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

#medicalknowledgeonline
Phenylephrine is a selective alpha-1 adrenergic agonist used as a decongestant, vasopressor, and mydriatic agent. It works by causing vasoconstriction, which reduces nasal congestion and raises blood pressure, but should be used cautiously due to risks like hypertension and rebound congestion.

*************************
Contents :
1. Generic Name, Drug class, Brande Name, 0:04
2. What is?, 0:28
3. Mechanism of Action 0:43
4. indication , 1:04
5. contraindication .1:17
6. Before taking this medicine (Precautions ), 1:31
7. How to use , 1:50
8. Dosing information, 2:12
9. Miss a dose, Overdose , 2:42
10. Stop or Avoid Taking , 3:02
11. Side Effects, 3:19
12. vital information , 3:47
13. Other Drugs Will Affect 4:05
#medicalknowledgeonline ,
- Generic Name, Drug class, Brande Name ,Precautions , How to use, Side Effects
***************************************
Content Disclaimer
"This video provides educational content for informational purposes only and is not a substitute for medical advice, diagnosis, or treatment. Always consult your healthcare provider with any questions regarding a medical condition or treatment. We do not endorse any specific treatments, medications, or products discussed on this channel."
********************************************************************
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Does Phenylephrine Make You Drowsy? In this informative video, we will discuss the effects of phenylephrine, a widely used nasal decongestant. This medication is known for its ability to relieve nasal congestion by narrowing blood vessels in the nasal passages, which helps reduce swelling. Unlike many other cold medications that can cause drowsiness due to their antihistamine content, phenylephrine operates differently.

We will cover how phenylephrine works and its potential side effects, including feelings of alertness and insomnia. If you are considering using phenylephrine for nasal congestion relief, it’s important to understand how it may affect your daily activities, particularly your sleep patterns. We will also talk about the importance of timing when taking this medication and the potential interactions with other drugs that could influence your overall experience.

If you’ve been wondering whether phenylephrine is the right choice for you, this video aims to provide clarity and guidance. Join us for a detailed discussion on this popular medication and subscribe to our channel for more helpful information on medicines and their effects.

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#Phenylephrine #NasalDecongestant #ColdMedication #MedicationSideEffects #StayAlert #Insomnia #NasalCongestion #HealthTips #PharmacyAdvice #OverTheCounter #MedicationInformation #Healthcare #DrugInteractions #AllergyRelief #SleepHealth

About Us: Welcome to Pharmaceutical Insights! Our channel is dedicated to providing clear and informative content on a variety of topics related to pharmaceutical drugs, prescription medications, over-the-counter medicines, drug side effects, and medication safety. We also discuss medical treatments, alternative medicine, and pain management drugs, ensuring you have access to the information you need to make informed health decisions. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

What Are The Side Effects Of Phenylephrine Eye Drops? In this informative video, we will discuss the side effects associated with the use of phenylephrine eye drops, commonly utilized in optometry for pupil dilation during eye exams and procedures. Understanding the potential reactions to these drops is important for both patients and practitioners. We will cover the typical side effects that many individuals may experience after application, such as sensations of burning or stinging, blurry vision, and increased light sensitivity. Additionally, we will touch on some of the more serious reactions, which, although rare, can occur and require immediate attention.

Patient safety is a priority in optometry, and monitoring for any adverse effects is essential, especially for those with pre-existing health conditions. We will also provide guidance on what patients should do after receiving these drops, particularly regarding activities that require clear vision. If severe reactions occur, alternative dilation options may be available, and we will briefly mention those as well.

Join us for this important discussion, and don't forget to subscribe to our channel for more informative content related to eye health and optometry practices.

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#Phenylephrine #EyeDrops #PupilDilation #Optometry #EyeHealth #VisionCare #EyeExam #SideEffects #PatientSafety #LightSensitivity #BlurredVision #AllergicReactions #HeartHealth #EyeCareTips #Optometrist #DilationAgents

About Us: Welcome to Optometry Knowledge Base, your go-to resource for all things related to optometry! Our channel is dedicated to providing in-depth insights into eye health, vision care, and the latest advancements in the field of optometry. Whether you're a student looking to deepen your understanding, a practicing optometrist seeking to stay updated, or simply someone interested in learning more about eye care, you’ll find valuable content here. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

#medicalknowledgeonline ,
What is ACETAMINOPHEN, PHENIRAMINE, AND PHENYLEPHRINE ? ,
Vital information,
Before taking this medicine (Precautions ),
How to use ,
Dosing information
Miss a dose, Overdose ,
Stop or Avoid Taking ,
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Other Drugs Will Affect,
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In this video you will come to know the uses side effects and dosage of phenylephrine drug.



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FDA panel calls congestion ingredient Phenylephrine “ineffective” in tablet form [(965757)] | Read the full story: https://keyt.com/lifestyle/you....r-money/2023/09/13/f

What Is Phenylephrine? In this informative video, we will discuss phenylephrine, a medication commonly used for relief from nasal congestion. We will explain what phenylephrine is and how it works in the body to alleviate symptoms associated with a stuffy nose. You will learn about its mechanism of action, including how it constricts blood vessels in the nasal passages to reduce swelling and improve airflow.

Additionally, we will cover the various applications of phenylephrine beyond treating nasal congestion. This includes its use in raising blood pressure in certain medical situations and its role in ophthalmology for pupil dilation during eye examinations. We will also touch on the pharmacological aspects of phenylephrine, comparing it to natural substances like norepinephrine and discussing its selectivity in receptor activation.

While phenylephrine is available over the counter in many countries, we will emphasize the importance of understanding its potential side effects, especially for individuals with specific health conditions. Join us for this detailed discussion on phenylephrine, and don't forget to subscribe to our channel for more informative content on general medicine and health topics.

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#Phenylephrine #NasalCongestion #Decongestant #BloodPressure #Ophthalmology #PupilDilation #Healthcare #Medicine #Pharmacology #HealthTips #ColdRelief #OverTheCounter #MedicalInformation #NasalSpray #GeneralMedicine

About Us: At The Health Brief, we are dedicated to making general medicine accessible and engaging for everyone. Our channel focuses on a wide range of topics, including common health concerns, medical advancements, and wellness tips. We aim to empower viewers with knowledge that can help them make informed decisions about their health and well-being. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

In this episode, I discuss a medication known as phenytoin (Dilantin).

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Levetiracetam Tablets ip 500 mg Hindi | Levepsy 500 in Hindi | Levesam 500 Tablet | Levera 500

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Levetiracetam is an antiepileptic or anticonvulsant medicine used in epilepsy treatment, Convu;sion treatment, Head injury etc. Levetiracetam is available in market as levetiracetam tablet, levetiracetam injection usp and levetiracetam syrup. Levetiracetam Tablets ip have different strength as Levetiracetam 250 mg, Levetiracetam 500 mg, Levetiracetam 750 mg and Levetiracetam 1000 mg.

The popular brand name of Levetiracetam Tablets are:
1. Levepsy Tablet | levepsy 500 | levepsy 750 | levepsy | levepsy 1000 mg | levepsy 250 | levesam 500 tablet
2. Levesam Tablet | Levesam 250 | levesam 500 | levesam 750 in hindi | levesam
3. Levera Tablet | levera 500 |
4. Keppra Tablet

In this video we discuss about uses of levetiracetam tablet, side effect of levetiracetam tablet, how to take levetiracetam tablets etc. We also discuss about:
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4. Levetiracetam tablets ip 500mg
5. Levetiracetam injection uses in hindi
6. Levetiracetam injection
7. Levepsy 500 in hindi
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11. Levesam syrup
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- This is lesson n# 20 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Phenytoin ( Dilantin ): What is Phenytoin Used For? Phenytoin Dosage, Side Effects & Precautions

- In 3 minutes you'll learn about:

- What is Phenytoin ?
- Phenytoin mechanism of action, uses, dosage, side effects, and precautions...
- MORE DRUG INFO HERE:
https://www.youtube.com/watch?v=BM5dg5f2daE&t=2s&list=PLL3y4VLBMQfgmQqcppCvUdJvlsoQVlCvI&index=2

------------

- In this video we'll briefly discuss what is Phenytoin ( Dilantin ), how it works, what it's used for, the dose and side effects, contraindications and precautions.

- Phenytoin is an anticonvulsant agent. It blocks voltage-gated sodium channels by selectively binding to the channel in the inactive state and slowing its rate of recovery. Thereby stabilizing threshold against hyperexcitability.

- It is available as 30 mg, 50 mg and 100 mg tablets. And also available as oral suspension and as injection.

- Phenytoin is used in the treatment of epilepsy, except absence seizure (petit mal).
- it is used in the control of grand mal and psychomotor seizures, prevention and treatment of seizures occurring during or after neurosurgery, control of grand mal type of status epilepticus (using parenteral administration).

Dosage

- Seizures

- Adults: 300 to 400 mg/day (maximum 600 mg/day).
- Children: 3 to 8 mg/kg/day in 2 to 3 divided doses.

Duration

- According to clinical response

Contra-indications

- Do not administer in case of hypersensitivity to phenytoin.

Adverse effects

- May cause:
- gastro-intestinal disturbances: gingival hypertrophy, nausea, vomiting.
- neurological disorders: dizziness, visual disturbances, mental confusion.
- blood disorders: monitor blood counts if possible and administer folic acid in case of prolonged use, as it may cause folic acid deficiency.
- allergic reactions: cutaneous eruption, fever, adenopathy.

Precautions

- Do not stop treatment abruptly, decrease daily doses gradually.
- It is not recommended to combine phenytoin with oral contraceptives, sulphonamides, or chloramphenicol. Combination with other drugs must be closely monitored (diazepam, phenobarbital, digoxin, corticosteroids, etc.).
- Paracetamol may increase hepatotoxicity potential with chronic phenytoin use.
- Pregnancy: avoid
- Breast-feeding: avoid

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