Low T - Health Risks of Testosterone Therapy - Mayo Clinic. Dr. William Young.

In the realm of migraine management, Ajovy has garnered attention as an effective treatment option. Understanding Ajovy, its prefilled syringe, potential side effects like hair loss, and success stories is vital for those seeking relief from migraines.
Ajovy Overview: Ajovy is a noteworthy medication in migraine management. It belongs to a class of drugs called calcitonin gene-related peptide (CGRP) inhibitors, which play a crucial role in preventing migraines. The drug is administered via a prefilled syringe.
Ajovy Review: A comprehensive Ajovy review provides insights into its efficacy, tolerability, and overall impact on migraine frequency and intensity. Personal experiences shared by individuals who have used Ajovy can shed light on its benefits.
Ajovy Prefilled Syringe: Ajovy is commonly administered through a prefilled syringe. This form offers convenience and ease of use, allowing individuals to self-administer the medication after appropriate training and guidance.
Ajovy Prefilled Syringe vs Autoinjector: The Ajovy prefilled syringe and autoinjector are both effective modes of administration. The choice between the two depends on personal preference, ease of use, and comfort in handling either device.
Ajovy Hair Loss: Hair loss is a potential concern associated with Ajovy use. Understanding this side effect and its potential impact on individuals is crucial when considering Ajovy as a treatment option.
Ajovy Diary: Maintaining an Ajovy diary can aid in tracking migraine patterns, medication usage, and any observed side effects. This log is valuable for both individuals and healthcare providers to tailor the treatment plan effectively.
Ajovy Weight Gain: Weight gain is another potential side effect associated with Ajovy use. Understanding the risks and benefits, and discussing any concerns with a healthcare provider, is essential for informed decision-making.
Injecting Ajovy: Proper administration of Ajovy involves injecting the medication subcutaneously. Adhering to the correct injection technique and guidelines ensures optimal results and safety.
Ajovy vs Ajovy: The phrase "Ajovy vs Ajovy" might indicate comparisons or discussions about different experiences or effects of using Ajovy, emphasizing the importance of personalized treatment plans.
Ajovy Success Stories: Ajovy success stories provide encouragement and motivation for individuals seeking relief from migraines. Real-life experiences shared by those who have found relief with Ajovy can offer hope and inspiration to others.
In conclusion, Ajovy represents a significant advancement in migraine treatment. Understanding its forms, potential side effects, and success stories can help individuals make informed decisions about incorporating Ajovy into their migraine management plan.
Thank you.
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"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.



"

Learn about Ajovy, a medication for migraine prevention, with Dr. Caudill Miller. Find out how Ajovy can help manage migraine headaches in this informative video.
Welcome to our latest video discussing Ajovy, an innovative migraine preventative medication. This video explains in detail how Ajovy works, its potential side effects, and its effectiveness in treating migraines. We've compiled expert opinions, patient experiences, and medical studies to provide a comprehensive understanding of this drug. If you're seeking reliable information on Ajovy, whether you're a patient, healthcare provider, or simply intrigued by medical advancements, this video is for you. Remember to hit the subscribe button for more informative content on a range of medical topics.

Why Suffer from Migraine Headaches when you can take and Ajovy injection to end the suffering

Ajovy (fremanezumab-vfrm) is an injectable prescription medicine used to prevent migraine headaches in adults.
Ajovy works by blocking the activity of calcitonin gene-related peptide (CGRP).
Ajovy may also be used for purposes not listed in this medication guide.

With the recent FDA approval of fremanezumab (Ajovy, Teva Pharmaceuticals) and other calcitonin gene-related peptide (CGRP) inhibitors for the prevention of migraine, many patients and headache specialists alike let loose a sigh of relief, welcoming these new medicinal capabilities to their arsenal.

Although, issues and challenges for these patients with migraine remain. Despite the great efficacy of these CGRP-inhibiting agents, with regard to these therapies, one of the less often discussed topics is their impact on migraine’s detrimental effects on quality of life, as well as its comorbidities. CGRP inhibitors reduce headache days, yes, but fremanezumab has now also been shown to have a positive effect on measures of quality of life, such as depression.

To share some insight into how fremanezumab has helped to improve these facets of the condition, Joshua Cohen, MD, the Global Medical Lead for Migraine and Headache at Teva Pharmaceuticals, sat with NeurologyLive at the American Neurological Association’s 143rd Annual Meeting.

.

Chapters

0:00 Introduction
0:48 Uses of Ajovy
1:06 Potential side effects of Ajovy
1:57 Important considerations




If you suffer from migraines, you know how debilitating they can be, affecting your daily life and overall well-being. Ajovy offers hope for millions of people looking for an effective solution to manage their migraines. In this video, we'll delve into what Ajovy is, how it works, its potential benefits, side effects, and important considerations.

Understanding Migraines:
Before we dive into Ajovy, let's briefly understand what migraines are. Migraines are severe headaches often accompanied by nausea, sensitivity to light and sound, and visual disturbances. They can significantly impact a person's quality of life, affecting work, relationships, and daily activities.

What is Ajovy?
Ajovy is a groundbreaking medication designed specifically for migraine prevention. It belongs to a class of drugs called CGRP inhibitors, which target calcitonin gene-related peptide receptors involved in migraines.

How Does Ajovy Work?
Ajovy works by blocking the activity of CGRP, a neurotransmitter associated with migraines. By inhibiting CGRP, Ajovy helps reduce the frequency and intensity of migraines.

Benefits of Ajovy:
Ajovy has shown promising results in clinical trials, demonstrating a reduction in migraine days for many patients. It offers an alternative for those who may not find relief with other treatments.

Administering Ajovy:
Ajovy is typically administered as a once-monthly injection, making it a convenient and easy treatment option for migraine prevention.

Potential Side Effects:
While Ajovy is generally well-tolerated, it may have some side effects. Common side effects include injection site reactions and mild allergic reactions. It's essential to discuss any concerns with your healthcare provider.

Important Considerations:
Before starting Ajovy, inform your doctor about your medical history, current medications, and any allergies. Ajovy may not be suitable for everyone, so your healthcare provider will assess if it's the right choice for you.

Ajovy Success Stories:
Many patients have experienced life-changing results with Ajovy. We'll share some inspiring stories of individuals who have found relief from their chronic migraines with Ajovy.

Frequently Asked Questions:
We'll answer common questions about Ajovy, such as its effectiveness, potential interactions, and how it compares to other migraine medications.

Conclusion:
If you're struggling with migraines and seeking a more effective way to manage them, Ajovy might be the solution you've been looking for. Consult your doctor to discuss if Ajovy is suitable for you and take the first step towards living a life with fewer migraines and more comfort.

Remember, this blog is for informational purposes only and not a substitute for professional medical advice. Always consult your healthcare provider before starting any new medication or treatment.

Discover what Aimovig does for migraine prevention and explore how it works and possible side effects. Share your experiences in the comments!

## Introduction to Aimovig
- Definition: Aimovig, with the full biological name Erenumab AOE, is a monthly injectable medication designed for adults to prevent migraines. It is self-administered subcutaneously, meaning just under the skin.

- Mechanism of Action: Aimovig functions by inhibiting the calcitonin gene-related peptide (CGRP), a small protein involved in pain transmission that increases during migraine attacks and contributes to their onset.

## CGRP Inhibitors Overview
- Types: There are two primary types of CGRP inhibitors used to manage migraines: monoclonal antibodies, such as Aimovig, and CGRP receptor antagonists often referred to as gepants.

- Approval Status: Aimovig was approved by the FDA on May 17, 2018, and as of this date, no generic version of the medication exists.

## Potential Side Effects
- Serious Reactions: Aimovig can cause significant side effects, including allergic reactions characterized by rash or swelling, and in severe cases, may lead to hospitalization due to constipation or high blood pressure issues.

- Common Effects: Side effects frequently reported by more than 3% of patients include pain, redness, or swelling at the injection site, constipation, and elevated blood pressure.

## Usage Instructions
- Administration: Use Aimovig as instructed by a healthcare provider, employing either a pre-filled autoinjector or a syringe, and ensure it's injected into the abdomen, thigh, or upper arm while avoiding the naval area.

- Preparation and Handling: Allow the medication to reach room temperature for 30 minutes before use and protect it from sunlight. Do not reuse the syringe or autoinjector, and discard it even if medication remains.

## Dosage Recommendations
- Standard Dosage: The recommended dosage is 70 milligrams monthly, though some individuals may require a dosage of 140 milligrams per month based on their healthcare provider's assessment.

00:00 What is Aimovig
00:40 How Aimovig Works
02:02 Usage Instructions
03:28 Important Warnings

#aimovig #whatisimovig #whatisaimovigusedfor #migraineprevention #cgrpinhibitors #monoclonalantibody #aimovigsideeffects #aimovigdosage #migrainetreatment #cgrpreceptorantagonist #aimoviginjection #ernumab #migrainemedication #subcutaneousinjection #aimovigadministration #migrainerelief #aimovigwarnings #howtoinjectaimovig #ajovyvsaimovig #newmigrainemeds #aimoviginstructions

Aimovig is a brand-name and the generic is Erenumab. In May 2018 it was the first CGRP which Works on receptor site. It blocks CGRP thereby blocks a migraine. It is given once a month at 70 to 140 mg subcutaneously that is under the skin. The half-life is 28 days. The side effects are Injection site reaction, constipation, some hypertension. Contraindications are hypersensitive reaction to the medicine or anaphylaxis and then you edema for me to discontinue the medicine and seek medical advice right away. Constipation is a major problem. You can keep it in the refrigerator but if you leave it outside the room temperature for seven days it’s OK beyond that you need to discard the medicine. It has excellent track record of preventing the migraine. It is a monoclonal antibody. It is for migraine prophylaxis or migraine prevention.
#aimoving #erenumab #migraine #migrainesymptoms #migrainetreatment #migrainerelief #prevention #migrainepain #monoclonalantibodies #antibody #CGRB #inhibitor #sideeffects #headice





Disclaimer

Views and opinions expressed on our site are not the views or pinions of anybody else but the author’s independent opinion & teaching point and will not constitute final word rather you need to read further on that subject. He or she including us are advising you that this is not a medical / legal advice. We are not giving you medical advice. The author is not implying any medical advice. The dosage and the material submitted should be confirm with the medical literature. We are not giving you any medical advice. We are not giving you any legal advice. We are not giving you any guarantees or promises of any of the products or services. The material presented in our blog and videosare to be used at the discretion of the reader in the viewer, Our site is provided for informational and educational purposes only. It does not, will not, should not, would not substitute medical advice and medical office /hospital/ER visits.

In one study, patients given Aimovig saw their migraine days cut from eight to four a month, on average. Lisa Sigell reports.

Aimovig (erenumab-aooe) is a once-monthly, self-administered injection used to prevent migraines in adults. It helps prevent migraines before they start and reduces the number of migraine days per month. Aimovig is given as an injection under the skin (subcutaneous injection) using a single-dose prefilled autoinjector or a single-dose prefilled syringe.

How it works?

Aimovig works by blocking the effect of calcitonin gene-related peptide (CGRP), a small protein involved in migraines that increases during a migraine attack. By blocking CGRP, Aimovig stops interaction between CGRP and the CGRP receptor which helps to prevent migraines.

Aimovig side effects

The most common Aimovig side effects include:

pain, redness, or swelling at the injection site (6%)

constipation (1%)

cramps, muscle spasms

These common side effects are for the 70mg dose.

Aimovig may cause serious side effects, including:

Allergic reactions, Severe constipation and High blood pressure or worsening of high blood pressure. High blood pressure or constipation are possible long-term side effects of this medicine.

Aimovig dosage

Usual Aimovig dose is 70mg once a month.

Some people may benefit from a dosage of 140mg. Aimovig 140mg is taken once a month.

Warnings

Aimovig may cause allergic reactions. If a serious allergic reaction occurs, stop injecting and go to the emergency room. Hypersensitivity reactions can occur within hours to more than one week after administration.

May also cause constipation with serious complications and new-onset or worsening of pre-existing high blood pressure may occur.

Lawrence Robbins, MD, Robbins Headache Clinic, Riverwoods, IL, discusses the safety profile of CGRP-directed antibodies in migraine and how clinical studies can be improved. After 3 years, 50,000 adverse events in migraine patients receiving CGRP-directed antibodies have been reported by the FDA. Many side effects of CGRP therapy, such as constipation and hypertension, have emerged after initial studies predicted a much milder safety profile. This may be explained by clinical trials often lacking a checklist for adverse events, which has been associated with missed side effects in 67% of patients. Studies are also often underpowered by cohort size and time. Overall, clinical trials need to be improved to more accurately represent potential side effects. The short- and long-term side-effects of CGRP antibodies in migraine need to be uncovered. This interview was conducted during the virtual 2021 World Congress on Controversies in Neurology (CONy) meeting.

This short video will help you learn how to use a Diskus the right way so that you can breathe better. All medicine should be taken under the care of your doctor.

Advair Diskus is used for long-term treatment of asthma and chronic obstructive pulmonary disease (COPD) in certain patients. It may also be used to treat other breathing conditions as determined by your doctor.
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Don’t use ADVAIR if.

• Do not use ADVAIR to treat sudden breathing problems from asthma or COPD. Always have a rescue inhaler with you to treat sudden symptoms.
• Do not use ADVAIR DISKUS if you have a severe allergy to milk proteins. Do not use ADVAIR if you are allergic to any of the ingredients in the products. Ask your healthcare provider if you are not sure.
• Do not use ADVAIR more often than prescribed.
• Do not take ADVAIR with other medicines that contain a LABA for any reason.
• Tell your healthcare provider about all the medicines you take and about all of your health conditions.
• Call your healthcare provider or get medical care right away if your breathing problems get worse, if you need your rescue inhaler more often than usual or it does not work as well to relieve your symptoms, or if your peak flow meter results decrease. Your healthcare provider will tell you the numbers that are right for you.
• ADVAIR can cause serious side effects, including:
• fungal infection in your mouth or throat (thrush). Rinse your mouth with water without swallowing after using ADVAIR to help reduce your chance of getting thrush.

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What is Advair Diskus used for?


Advair Diskus, Advair HFA, AirDuo Respiclick is used to treat difficulty breathing, wheezing, shortness of breath, coughing, and chest tightness caused by asthma. Advair Diskus is also used to prevent and treat wheezing, shortness of breath, coughing, and chest tightness caused by chronic obstructive pulmonary disease (COPD; a group of lung diseases that includes chronic bronchitis and emphysema). Advair Diskus is used in adults and children 4 years of age and older. Advair HFA, AirDuo Respiclick are used in children 12 years of age and older.


How should this medicine be used?


Advair Diskus comes as a powder and as an inhalation solution to inhale by mouth using a specially designed inhaler. It is usually used twice a day, in the morning and evening, about 12 hours apart. Use Advair Diskus at around the same times every day. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Use Advair Diskus exactly as directed. Do not use more or less of it or use it more often than prescribed by your doctor.

Talk to your doctor about how you should take your other oral or inhaled medications for asthma during your treatment with salmeterol and fluticasone inhalation. If you were using a short-acting beta agonist inhaler such as albuterol (Proventil, Ventolin) on a regular basis, your doctor will probably tell you to stop using it regularly but to continue to use it to treat sudden attacks of asthma symptoms. Follow these directions carefully. Do not change the way you use any of your medications or stop taking any of your medications without talking to your doctor.

Do not use fluticasone and salmeterol during an attack of asthma or COPD. Your doctor will prescribe a short-acting inhaler to use during attacks.

Advair Diskus inhalation controls the symptoms of certain lung diseases but does not cure these conditions. It may take a week or longer before you feel the full benefit of Advair Diskus. Continue to use Advair Diskus even if you feel well. Do not stop using Advair Diskus without talking to your doctor. If you stop using Advair Diskus inhalation, your symptoms may return.

Before you use Advair Diskus, Advair HFA, or AirDuo Respiclick for the first time, read the written package instructions that come with it. Look at the diagrams and package instructions carefully and be sure that you recognize all the parts of the inhaler. Ask your doctor, pharmacist, or respiratory therapist to show you how to use the inhaler. Practice using your inhaler while they watch, so you are sure you are doing it the right way.

If your child will be using fluticasone and salmeterol inhalation, be sure that he or she knows how to use it. Watch your child each time they use the inhaler to be sure that they are using it correctly.

Never exhale into the inhaler, take the inhaler apart, or wash the mouthpiece or any part of the inhaler. Keep the inhaler dry. Do not use the inhaler with a spacer.


What special dietary instructions should I follow?


Talk to your doctor about eating grapefruit or drinking grapefruit juice while taking this medication.


What should I do if I forget a dose?


Skip the missed dose and continue your regular dosing schedule. Do not inhale a double dose to make up for a missed one.


What side effects can Advair Diskus cause?


Advair Diskus may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

runny nose.
sneezing.
sore throat.
throat irritation.
sinus pain.
headache.
nausea.
vomiting.
diarrhea.
stomach pain.
muscle and bone pain.
dizziness.
weakness.
tiredness.
sweating.
tooth pain.
shaking of a part of your body that you cannot control.
sleep problems.

In this episode of Know Your Drug, Brothers Jake Messina and Matthew Gaeto discuss the prescription drug Advair Diskus (fluticasone/salmeterol). Advair is commonly prescribed to prevent chronic obstructive pulminary disease (COPD). This information is a general guideline and is not meant to replace physician orders. Patients using Advair should use this medication according to their prescriber!

Please let me know if you experience any of these side effects!

Ms. Diane Tin shares why #medications are important to treat #rheumatoid #arthritis (RA) and help control RA symptoms to limit any damage it may cause. She also discusses what you should do if you have side effects from medications and who you should talk to about side effects (in addition to your doctor).

Dr. David Liew discusses abstract OP0065, "Tocilizumab in Visual Involvement of Giant Cell Arteritis. Multicenter Study of 312 Patients of Clinical Practice", presented at the virtual EULAR 2021 meeting.

Here’s a bad side effect you need to be aware of if you’re taking this particular drug.

Tocilizumab (Actemra) markedly increases rate of bowel perforation.

Amy Karon writing in Rheumatology News reported that patients with rheumatoid arthritis were 5 to 9 times more likely than patients on other biologics to develop perforation of the colon. The report comes from a study conducted in Germany after analysis of more than 15,000 patients with rheumatoid arthritis evaluated through the German biologics registry.

Comment: A well known risk but the incidence is a lot higher than we supposed.

In this comprehensive guide to Tocilizumab, we delve into its mechanism of action, various uses in medical treatment, recommended dosages, potential side effects, and important precautions to consider. Whether you are a healthcare professional or a patient looking for detailed information on Tocilizumab, this video will provide you with all the essential knowledge you need in 2024. Stay informed and educated about this important medication with our in-depth exploration.
Make sure to watch till the end to gain a thorough understanding of Tocilizumab.

#Tocilizumab #MedicationGuide #Healthcare2024

The information provided in this video is for educational and informational purposes only and is not intended as medical advice. It is not a substitute for professional medical diagnosis, treatment, or advice. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have learned from this video or any linked materials.

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Chapters

0:00 Introduction
0:51 Uses of Actemra
1:45 Potential side effects of Actemra
3:08 Important consideratiom





In the realm of medical science, there are constant efforts to develop groundbreaking treatments for various health conditions. Actemra, an innovative medicine, has emerged as a ray of hope for individuals suffering from autoimmune disorders and chronic inflammatory conditions. Today, we will delve into the wonders of Actemra, exploring its mechanism of action, benefits, potential side effects, and real-life success stories.

Understanding Actemra:
Actemra is a revolutionary medicine that targets the immune system to combat inflammation. It belongs to a class of medications known as interleukin-6 receptor inhibitors, specifically targeting cytokine release syndrome associated with certain inflammatory disorders.

Treating Rheumatoid Arthritis:
One of the primary applications of Actemra is in the treatment of rheumatoid arthritis. It helps alleviate joint pain, stiffness, and inflammation, providing much-needed relief to patients.

Addressing Cytokine Release Syndrome:
Cytokine release syndrome is a severe immune response that can occur with certain medical treatments. Actemra plays a crucial role in managing this condition, preventing its potentially life-threatening consequences.

Benefits of Actemra:
Actemra offers numerous advantages, including improved joint function, reduced pain, and a better quality of life for patients battling inflammatory conditions.

Potential Side Effects:
Like any medication, Actemra may have side effects. Understanding these potential risks is essential for patients and healthcare providers to make informed decisions.

Dosage and Drug Information:
Knowing the right dosage and adhering to the prescribed treatment plan are vital aspects of Actemra therapy. We explore the recommended dosage and essential drug information in this section.

Real-Life Success Stories:
Witnessing the transformative power of Actemra is awe-inspiring. We present touching testimonials from patients whose lives have been positively impacted by this medication.

Actemra in Clinical Trials:
The development and efficacy of Actemra were extensively evaluated through clinical trials. We discuss the key findings from these trials, providing a comprehensive understanding of its performance.

Actemra as an Immunosuppressant:
We explore Actemra's role as an immunosuppressant and its significance in managing autoimmune disorders and reducing inflammatory responses.

The Future of Actemra:
Actemra represents a significant milestone in healthcare innovation. We look forward to advancements and potential new applications for this groundbreaking medication.

Conclusion:
Actemra has emerged as a game-changer in the treatment of autoimmune disorders and inflammatory conditions. Its unique mechanism of action and numerous benefits provide hope to millions of patients worldwide. As we delve deeper into the realm of medical breakthroughs, Actemra stands as a testament to the relentless pursuit of a healthier future for all.

Abiraterone: Uses, Dosage, Side Effects & Warnings

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Panelists Raoul S. Concepcion, MD; Daniel P. Petrylak, MD; Michael S. Cookson, MD, MMHC; and Neal D. Shore, MD, discuss the efficacy and safety considerations in abiraterone/prednisone, and share toxicity management strategies.

One of the standard medications to treat prostate cancer can cost $10,000 a month, but now researchers in Chicago have come up with a creative way to get a maximum benefit from the drug by combining a lower dose with food. CBS 2's Irika Sargent reports.

Dr Alibhai speaks with ecancertv at SIOG 2016 about the experience of men receiving abiraterone or docetaxel for the treatment of metastatic castrate resistant prostate cancer.

He discusses how the efficacy was similar to prior published studies, and how toxicities were slightly greater.

Andrew Armstrong, MD, Duke University, Durham, NC, discusses the five-year outcomes of the AbiRT trial (NCT05177042), which evaluated a six-month course of abiraterone acetate, prednisone, and androgen deprivation therapy (ADT) combined with curative-intent radiation in patients with high-risk prostate cancer. The study demonstrates that a significant majority of patients remain in remission with minimal toxicities and successful recovery of testosterone levels within a year. This promising short-course therapy offers a potential new approach for managing high-risk prostate cancer. This interview took place at the 2024 Advanced Prostate Cancer Consensus Conference (APCCC) in Lugano, Switzerland.

These works are owned by Magdalen Medical Publishing (MMP) and are protected by copyright laws and treaties around the world. All rights are reserved.

Leonard Gomella, MD, professor, Jefferson University, physician, chair, Department of Urology, director, Kimmel Cancer Center Network, discusses results from a study that assessed the corticosteroid-associated adverse events with long-term exposure to low-dose prednisone given with abiraterone acetate to patients with metastatic castration-resistant prostate cancer (mCRPC).