Norethindrone Ac (Lupaneta) is a medication used to treat women with abnormal bleeding from the uterus. It can also be used for women who have stopped having menstrual periods for several months, but are not pregnant or going through menopause. Additionally, it is used to treat endometriosis, a condition in which tissue that normally lines the inside of the uterus is found outside the uterus in the abdomen/pelvic area, causing painful/irregular periods.

Norethindrone is a type of hormone called progestin, similar to the hormone progesterone that the body naturally makes. This medication works by stopping the normal growth of the uterus lining during the menstrual cycle and signaling hormone changes in the uterus to restore normal menstrual periods.

It's important to note that this medication should not be used to test for pregnancy. Additionally, progestins are not effective in preventing miscarriages.

As for the daily dosage and optimal timing, it's best to follow the instructions given by your healthcare provider. Be sure to take the medication at the same time each day to maintain its effectiveness.
6826

This combination hormone medication is used to prevent pregnancy. It contains 2 hormones: norethindrone (a progestin) and ethinyl estradiol (an estrogen). This product also contains a small amount of iron (ferrous fumarate) in inactive tablets taken during the fourth week. The inactive pills do not contain any hormones. These tablets are meant to keep you in the habit of taking 1 tablet each day and do not have enough iron to treat iron deficiency. Besides preventing pregnancy, birth control pills may make your periods more regular, decrease blood loss and painful periods, decrease the risk of ovarian cysts, and also treat acne. Remember to take 1 tablet each day at the same time to maintain its effectiveness. Using this medication does not protect you or your partner against sexually transmitted diseases.
f928

Norethisterone 5mg tablets are commonly used to delay periods, treat heavy or irregular bleeding, and manage endometriosis. In this video, we’ll cover:
✅ What is Norethisterone?
✅ How it works & when to take it
✅ Common uses (Period Delay, Heavy Periods, HRT, etc.)
✅ Possible side effects & risks
✅ Precautions & who should avoid it

⚠️ Disclaimer: Always consult a doctor before taking any medication.

📌 Timestamps:
00:00 – Introduction
00:30 – What is Norethisterone?
01:15 – Uses & Benefits
02:45 – Dosage & How to Take It
04:00 – Side Effects & Risks
06:00 – Precautions & Warnings

🔔 Subscribe for more health videos!

YouTube Tags:

#Norethisterone #PeriodDelay #MenstrualHealth #HormonalTreatment #WomensHealth #HeavyPeriods #Endometriosis #MenstrualCycle #HormonalPills #PeriodCare #NorethisteroneSideEffects #HealthTips #MedicineGuide

Hello friends
Today we discuss about norethisterone tablets primolut n tablets norlut n tablets uses in hindi are hormonal tablets use to treat problems related to monthly periods of female.
Uses
Side effects
Warnings
Dosage
And many more
Watch full video

ALL ABOUT MEDICINE
With mohit dadhich

#lam
#mohitdadhcih
#learnaboutmedicine
#norethisterone
#registrone
#allaboutmedicinenorthi

Regestrone (Northindrone) 5mg Tablet Use Dose Side Effects and Precautions explained here in hindi

Regestrone 5mg Tablet is used to treat various menstrual problems including painful heavy or irregular periods premenstrual syndrome (PMS) and a condition called endometriosis. It is a man-made version of the natural female sex hormone progesterone.

#regestronetablet #norethindrone #norethisterone #mentrualcycle #Regestrone5mg

Regestrone Tablets ke Side-Effect. Regestrone टेबलेट खाने के नुकसान.

#DrBabitaRathore
#BabitaHealthTips
#FastConceiveTips
#Pregnancytest
#Pregnancytestkaborkesekre
#Unwantedkitusevidio
#Abortioninformation
#HemaMahara
#PregnancytipsandAdvice
#drbabitarathore
#MifegestkitUseVidio

Aygestin Norethindrone offers a range of benefits for women seeking hormonal regulation. Firstly, it can effectively regulate the menstrual cycle, making it an ideal choice for those with irregular periods. By providing a steady dose of progesterone, it helps establish a predictable and regular menstrual cycle, alleviating the stress and uncertainty caused by irregular bleeding.
Additionally, Aygestin Norethindrone is commonly prescribed to manage endometriosis, a condition in which the tissue lining the uterus grows outside of it. This can cause severe pain and infertility. By suppressing ovulation and reducing the growth of endometrial tissue, Aygestin Norethindrone helps control the symptoms of endometriosis and improve overall quality of life for those affected by this condition.
Furthermore, Aygestin Norethindrone is effective in reducing heavy menstrual bleeding, a common problem faced by many women. Excessive bleeding can lead to anemia and significantly impact daily activities. By stabilizing hormone levels and regulating the menstrual cycle, Aygestin Norethindrone can help reduce the severity and duration of heavy bleeding, providing much-needed relief.
How Aygestin Norethindrone works.
Aygestin Norethindrone works by mimicking the effects of progesterone in the body. It inhibits the release of follicle-stimulating hormone (FSH) and luteinizing hormone (LH) from the pituitary gland, which in turn prevents ovulation. By suppressing ovulation, Aygestin Norethindrone helps regulate the menstrual cycle and reduces the symptoms associated with hormonal imbalances.
Additionally, Aygestin Norethindrone thickens the cervical mucus, making it more difficult for sperm to reach the egg. This further decreases the chances of pregnancy, making Aygestin Norethindrone an effective contraceptive option for women looking to prevent pregnancy while also managing their hormonal imbalances.
It is important to note that Aygestin Norethindrone should be taken consistently and as prescribed by a healthcare professional to ensure its effectiveness. Skipping doses or taking it irregularly may decrease its efficacy and compromise the desired hormonal regulation.
Dosage and administration guidelines.
The dosage of Aygestin Norethindrone may vary depending on the specific condition being treated and individual patient factors. It is crucial to consult with a healthcare provider to determine the appropriate dosage for your needs.
Typically, Aygestin Norethindrone is taken orally in the form of tablets. The medication is usually started on the first or fifth day of the menstrual cycle and taken for a specific duration as prescribed by the healthcare provider. It is important to follow the prescribed schedule and complete the full course of treatment for optimal results.
In cases where Aygestin Norethindrone is used as a contraceptive, it is important to take it consistently every day, preferably at the same time each day. This ensures that the hormone levels remain stable and the contraceptive effect is maintained.
Potential side effects and precautions.
Like any medication, Aygestin Norethindrone may cause side effects in some individuals. Common side effects include bloating, breast tenderness, nausea, headache, and changes in menstrual bleeding patterns. These side effects are usually mild and temporary, but if they persist or become bothersome, it is important to consult a healthcare provider.
In rare cases, Aygestin Norethindrone may cause more serious side effects, such as blood clots, liver problems, or allergic reactions. It is important to be aware of these potential risks and seek medical attention immediately if any unusual symptoms or severe side effects occur.
It is also important to disclose any existing medical conditions or medications you are taking to your healthcare provider before starting Aygestin Norethindrone. Certain conditions, such as liver disease or a history of blood clots, may increase the risks associated with this medication. Your healthcare provider will be able to determine if Aygestin Norethindrone is a suitable option for you based on your individual circumstances.
-----
"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately.

💬 Curious about Norethindrone? Whether you're using it for birth control, endometriosis, or hormonal balance, I break down real user experiences and what you need to know before starting it.

In this video, I cover:
• What Norethindrone is & how it works
• Common side effects (acne, spotting, mood changes, etc.)
• My personal 30-day experience
• Is it safe to take long-term?
• Norethindrone vs combination pills – which is better for you?
• Who should (and shouldn’t) consider it in 2025

🧪 Reviewed: May–June 2025
📌 Use cases: birth control, period regulation, endometriosis, menopause support

📌 Watch Next:

Best Birth Control Pills in 2025 – Pros & Cons 👉 [Link]

Norethindrone vs Drospirenone – Which Is Right for You? 👉 [Link]

💬 Comment: Are you on Norethindrone? How did it affect your mood, skin, or cycle? Share your story below to help others 👇

#NorethindroneReview #BirthControlPill2025 #MiniPillReview #HormoneTherapy2025 #NorethindroneSideEffects #WomenHealthReview #EndometriosisSupport #ProgesteronePills #BirthControlExperiences #NorethindroneHonestReview

Common side effects of contraceptive pills include high blood pressure, severe headaches, lower extremity pain, blood clots and loss of menses. Discover how using contraceptive pills can cause irregular periods with help from a physician's assistant in this free video on contraceptive pills.

Expert: Albert William Hedgepeth, Jr.
Bio: Al Hedgepeth is an alumnus of the University of North Carolina at Chapel Hill and earned his degree as a P.A. in 1980.
Filmmaker: Rendered Communications

This video explains some common side effects of nortriptyline tablets.

@ProfessorTushar

This is a drug review of nortriptyline (Pamelor), a tricyclic antidepressant. The mechanism of action, indications, dosing, adverse reactions, and comments were discussed.

#Nortriptyline #Pamelor #Antidepressant #Depression #Pain #Neuropathy

Disclaimer: This video is for information purposes only. Do not take nortriptyline without a prescription. The uploader of this video is not responsible for any loss or injuries of viewers.

Combinations, Avoid, Brand names, Medical use, About, Dosage, Side Effects, Drug interactions, Special precautions, Contraindications with pregabalin and gabapentin

Nortriptyline is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, and increase your energy level.

Video Content:
0:00 Nortriptyline tablets
0:25 Indications
0:38 How to use
1:37 Contraindications
2:30 Warnings
3:10 Side effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Nortriptyline #depression #medicine

Nortriptyline hydrochloride 25 mg uses | Nortriptyline for migraine |Nortriptyline 10mg

Nortriptyline is an anti depressant drug. nortriptyline is also known as nortriptyline hydrochloride tablets. nortriptyline is used used to treat Depression disorder, anxiety, nortriptyline for migraine/ Neuropethic pain | Nortriptylinefor nerve pain / neuralgia, helps to quit smoking, opium and alcohol.
Nortriptyline hydrochloride 25 mg uses | Nortriptyline for migraine |Nortriptyline 10mg brand name are
Pametor tablet
premox tablet
Nortipan tablet
nortilin tablet
Nortimer tablet, trynor tablet

we also discuss about nortriptylin hydrochloride tablet 25 mg / Nortriptyline reviews
Nortriptyline tablets brand name
nortriptyline hydrochloride tablets 25 mg uses in detail
doasge
side effects
and many more in hindi

like/ share/ subscribe

LEARN ABOUT MEDICNE

#lam
#nortriptyline
#nortriptylinetablet
#learnaboutmedicine

Welcome to MediInsights - Unlocking The Wonders of Wellness!
In today's video, we will explore Nortriptyline Tablets, a medication widely used for various health conditions. We’ll cover its uses, dosage, mechanism of action, side effects, and important advice for taking this medication. Let's dive in!

Uses of Nortriptyline Tablets:

Nortriptyline Tablets are primarily used to treat major depression. This versatile medication is also prescribed for chronic pain management, anxiety disorders, and certain types of neuropathic pain. Additionally, it may be used off-label to address conditions like migraines and attention deficit hyperactivity disorder (ADHD).

Dosage of Nortriptyline Tablets:

The dosage of Nortriptyline Tablets can vary based on the condition being treated, patient age, and individual response to the medication. For adults dealing with depression, the typical starting dose is 25 mg once daily, which can be gradually increased to a maintenance dose between 50 to 150 mg per day. Elderly patients often start at a lower dose, around 10 to 25 mg daily, to account for increased sensitivity to the drug. For chronic pain and other conditions, the starting dosage is generally lower, beginning at around 10 mg daily.

Mechanism of Action of Nortriptyline Tablets:

Nortriptyline belongs to the class of tricyclic antidepressants (TCAs). It functions by inhibiting the reuptake of neurotransmitters norepinephrine and serotonin in the brain, which increases their levels and prolongs their mood-enhancing effects. This mechanism helps alleviate symptoms of depression and improve mood, making it effective for other related conditions as well.

Side Effects of Nortriptyline Tablets:

Like all medications, Nortriptyline comes with potential side effects. Common side effects include dry mouth, drowsiness, dizziness, constipation, weight gain, and blurred vision. More serious side effects can involve arrhythmias, severe hypotension, seizures, and an increased risk of suicidal thoughts, especially in young adults and adolescents. It is crucial to monitor for these severe reactions and seek medical attention if they occur.

Important Advice for Using Nortriptyline Tablets:

Always take Nortriptyline exactly as prescribed by your healthcare provider.
Do not abruptly stop taking the medication without consulting your doctor to avoid withdrawal symptoms.
Avoid alcohol, as it can enhance drowsiness and dizziness.
Regular monitoring by a healthcare provider is essential to manage dosages and side effects effectively.
Inform your doctor about all other medications you are taking to avoid potential drug interactions.
Be cautious when driving or operating heavy machinery due to the potential for dizziness and drowsiness.
Conclusion:

Nortriptyline Tablets offer significant benefits for those suffering from depression, chronic pain, and other conditions. However, it's essential to follow your healthcare provider's instructions and be aware of potential side effects.

Thank you for watching MediInsights - Unlocking The Wonders of Wellness! If you found this video helpful, please like, share, and subscribe to our channel for more informative content on health and wellness. Don’t forget to hit the bell icon to stay updated with our latest videos.

Stay healthy and informed!

Disclaimer: This video is intended for educational and informational purposes only. The content provided is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or the use of medications. The information presented here is based on general knowledge and research and may not be applicable to individual circumstances. The creators of this video do not endorse or promote any specific medical products or treatment regimens. Viewers are encouraged to consult their healthcare provider for personalized medical advice. The content provided in this video complies with YouTube's community guidelines and policies.

CHAPTERS:
0:00 :INTRO
0:44 :USE OF NORTRIPTYLINE TABLETS
1:09 :DOSAGE OF NORTRIPTYLINE TABLETS
1:51 :MECHANISM OF ACTION OF NORTRIPTYLINE TABLETS
2:16 :SIDE EFFECTS OF NORTRIPTYLINE TABLETS
2:47 :IMPORTANT ADVICES FOR USING NORTRIPTYLINE TABLETS
#MediInsights #Nortriptyline #DepressionTreatment #ChronicPainRelief #MentalHealth #MedicationGuide #HealthTips #Wellness #Antidepressants #Pharmacology #Medicine #MentalWellbeing #HealthEducation #TricyclicAntidepressants #PatientAdvice #DrugSafety #Pharmacy #HealthAwareness #MedicalAdvice #WellnessJourney

This medication is used to treat mental/mood problems such as depression. It may help improve mood and feelings of well-being, relieve anxiety and tension, and increase your energy level. This medication belongs to a class of medications called tricyclic antidepressants. It works by affecting the balance of certain natural chemicals (neurotransmitters) in the brain.

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All viewers of this video recognize and acknowledge that all content presented in this video is solely for educational purposes. All viewers acknowledge and agree that if any methods, techniques or protocols learned in the video is used or implemented, it is done so appropriately, with individual discretion, for its intended purposes, and only after such individual receives guidance and advice from a professional practitioner that has evaluated and considered such individual’s situation and circumstances personally. Any methods, techniques or protocols presented in this video may have inherent risks when is individually used or implemented. Any viewer who uses or implements any learned methods, techniques or protocols found in this video recognizes such risks and acknowledge professional liabilities may result from individual use or implementation of learned methods, techniques or protocols.

All viewers should be aware of the potential risks, including, but not limited to, death or permanent medical illness, that can occur by individual use or implementation of the methods, techniques or protocols presented in this video.

All viewers agree that CPG Rx LLC and/or any affiliated businesses or persons do not have any legal obligations or duties to the actions performed by any viewer after viewing this video. All viewers consent to release CPG Rx LLC and/or any affiliated businesses or persons of all liabilities and obligations associated and related to any adverse actions or professional liability incurred as a result of using or implementing the methods, techniques or protocols learned in this video.

This is a drug review of amlodipine (Norvasc), an antihypertensive. The mechanism of action, indications, dosing, adverse reactions, and comments were discussed.

#Amlodipine #Norvasc #Antihypertensive #Hypertension #Angina #Heart #HighBloodPressure #Pharmacist

Disclaimer: This video is for information purposes only. Do not take amlodipine without a prescription. The uploader of this video is not responsible for any loss or injuries of viewers.

We've all seen it in our OPDs: a patient on Amlodipine comes back complaining of swollen feet (pedal edema). It's one of the most common reasons for non-compliance. Here's a quick clinical refresher on why it happens and how to manage it.
The "Why":
Amlodipine causes potent arteriolar dilation but less venular dilation. This imbalance increases capillary hydrostatic pressure, leading to fluid leakage into the interstitium.
What's the Solution? 💡
You have two excellent, evidence-based options:
ADD an ACE Inhibitor or ARB: Co-prescribing a drug like Telmisartan or Ramipril causes venodilation, which balances the hydrostatic pressure and often resolves the edema. This is why Amlodipine+Telmisartan is such a popular combination! 💊
SWITCH to Cilnidipine: Cilnidipine is an L/N-type calcium channel blocker that has a more balanced effect on arterioles and venules. Switching the patient from Amlodipine to Cilnidipine can resolve the edema while maintaining blood pressure control.
🚨 Crucial Safety Check: Before attributing edema solely to Amlodipine, always rule out systemic causes. A quick review for cardiac (CHF), renal, or hepatic dysfunction is mandatory.
What's your preferred strategy in your practice? Adding an ARB/ACEi or switching to Cilnidipine? Share your experience below! 👇
#HypertensionManagement #Amlodipine #ClinicalPearls #IndianDoctors #Pharmacology #DoctorsOfIndia #Tier2Healthcare #MedEd

Norvasc belongs to a group of medicines called calcium channel blockers or calcium ion antagonists.

Video Content:
0:00 Norvasc tablets
0:24 Indications
0:37 How to use
1:11 Contraindications
1:27 Warnings
2:06 Norvasc side effects

Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor.

#Norvasc #hypertension #medicine

Amlodipine is commonly used BP medicine but can cause constipation and edema , in addition to some other side effects.
Know all about it with how it works , side effects and uses. It comes with several brands and widely used in world and Pakistan.
Must watch this video so that you know about it.
Don’t take it without Drs prescription because it might not be good for you or there might be better drugs abia or for your condition.
#amlodipine #bloodpressurecontrol #nephchat #imchospital #drshafiqcheema

Susan L Samson, MD, PhD, FRCPC, FACE, Chair of Endocrinology at Mayo Clinic in Jacksonville, Florida, discusses the positive safety data from the open-label extension of the OPTIMAL study of oral octreotide, a drug approved for the treatment of acromegaly. Data from the open-label extension was presented at the ENDO 2022 Annual Conference.
Acromegaly is a rare endocrine disorder in which the body secretes too much growth hormone in adulthood, usually as a result of a pituitary tumor. Since the increased growth hormone occurs past puberty, the changes in bone structure can be very gradual. As a result, it can take several years for a person with acromegaly to be diagnosed.

As Dr. Samson explains, the OPTIMAL trial (NCT03252353) was a randomized, double-blind, placebo-controlled, phase 3 clinical trial of octreotide capsules in 56 adult acromegaly patients whose disease was controlled by injectable somatostatin analogs (octreotide or lanreotide). Eligible patients were then randomized 1:1 to octreotide capsules or placebo. The primary endpoint of the trial was the proportion of patients who maintained their biochemical response (insulin-like growth factor I [IGF-1] levels less than 1.0 × upper limit of normal [ULN]), at the end of the 9-month, double-blind, placebo-controlled period. The OPTIMAL study met the primary endpoint and all secondary endpoints which led to the US approval of oral octreotide, the first oral somatostatin analog, for the long-term maintenance treatment in acromegaly patients who have responded to and tolerated treatment with injectable octreotide or lanreotide.

After the 9-month, double-blind, placebo-controlled period, patients were eligible for enrollment in the open-label extension study to evaluate the long-term efficacy and safety of oral octreotide. Overall, the safety profile of oral octreotide during the open-label extension period was consistent with previous studies and with that of injectable somatostatin analogs. No serious adverse events were reported in the open-label extension study. Interestingly, Dr. Samson notes that patients who entered the open-label extension study naive to oral octreotide tended to have fewer adverse events compared to patients who were in the treatment arm of the clinical trial. One potential reason for this is that patients in the placebo arm were initially given 60 mg of oral octreotide when they entered the open-label extension, while those in the treatment arm were dose titrated from 40 mg per day to up to a maximum of 80 mg per day. Dr. Samson suggests that the higher dose may have better control of the manifestations of acromegaly which could explain the reduction in adverse events. Further evaluation is needed to determine this.

Welcome to MediInsights, where we unlock the wonders of wellness! In today's video, we delve into the essential details of Octreotide Injection, a crucial medication in the management of specific hormonal disorders and tumors.

Use of Octreotide Injection:
Octreotide injection is a powerful medication used primarily for treating symptoms related to metastatic carcinoid tumors and VIPomas, such as severe diarrhea and flushing. It's also a key treatment for acromegaly, a condition caused by excess growth hormone, and is utilized to prevent complications following pancreatic surgery.

Dosage of Octreotide Injection:
The dosage of octreotide varies depending on the condition and patient response. For acromegaly, the starting dose is typically 50 micrograms injected subcutaneously two or three times daily, with adjustments based on the patient’s needs. For treating carcinoid tumors and VIPomas, the initial dose can range from 100 to 600 micrograms per day, divided into multiple doses. Long-acting formulations like Sandostatin LAR are administered intramuscularly every four weeks, with dosages between 20 to 30 mg.

Mechanism of Action of Octreotide Injection:
Octreotide is a synthetic analog of somatostatin, a natural hormone that inhibits various other hormones. It binds to somatostatin receptors, reducing the secretion of growth hormone, serotonin, and other peptides like insulin and glucagon. This action helps manage symptoms by controlling excessive hormone production and secretion.

Side Effects of Octreotide Injection:
While octreotide is effective, it can cause some side effects. Common issues include gastrointestinal disturbances such as nausea, vomiting, abdominal pain, and diarrhea. Patients might also experience injection site reactions and gallstones due to reduced bile flow. Other potential side effects include blood sugar imbalances (hyperglycemia or hypoglycemia), bradycardia, hypothyroidism, and, with long-term use, vitamin B12 deficiency.

Important Advice for Using Octreotide Injection:
It's crucial to follow your healthcare provider's instructions carefully. Regular monitoring of blood glucose and thyroid function is recommended due to the endocrine effects of octreotide. Rotate injection sites to avoid tissue damage and report any severe side effects, such as intense abdominal pain or symptoms of gallstones, to your healthcare provider immediately. Regular check-ups are essential to adjust the dosage and ensure the treatment's effectiveness.

Thank you for watching MediInsights! If you found this video helpful, please like, comment, and subscribe to our channel for more in-depth health insights. Don't forget to hit the bell icon to get notified about our latest videos. Unlock the wonders of wellness with us!

Disclaimer: This video is intended for educational and informational purposes only. The content provided is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition or the use of medications. The information presented here is based on general knowledge and research and may not be applicable to individual circumstances. The creators of this video do not endorse or promote any specific medical products or treatment regimens. Viewers are encouraged to consult their healthcare provider for personalized medical advice. The content provided in this video complies with YouTube's community guidelines and policies.

CHAPTERS:
0:00 :INTRO
0:44 :USE OF OCTREOTIDE INJECTION
1:16 :DOSAGE OF OCTREOTIDE INJECTION
1:59 :MECHANISM OF ACTION OF OCTREOTIDE INJECTION
2:32 :SIDE EFFECTS OF OCTREOTIDE INJECTION
2:59 :IMPORTANT ADVICES FOR USING OCTREOTIDE INJECTION

#MediInsights #OctreotideInjection #HormoneTherapy #CancerTreatment #Acromegaly #Health #Wellness #Endocrinology #MedicalAdvice #HealthTips #WellnessJourney #MedicalEducation #PatientCare #Pharmacology #Medicine #Healthcare #MedicalInsights #HealthAwareness #WellnessTips #HormonalDisorders #TumorTreatment #HealthAndWellness

Could be:
SandoSTATIN
SandoSTATIN LAR Depot
Octreotide Acetate Omega
Class
Antidiarrheal
Antidote
Somatostatin analog

Forms
Intramuscular kit:
SandoSTATIN LAR Depot== 10mg, 20mg, 30mg

Injection:
SandoSTATIN 50ug/ml, 100ug/ml, 200ug/ml, 500ug/ml, 1000ug/ml


Through I.V/SubQ/ I.M/ Depot

Uses
1. DM
2. Chemotherapy
3. HIV
4. Graft vs Host
5. Carcinoid
6. Medullary Thyroid CA
7. VIPoma's
8. Short Bowel Syndrome
9. Bone Marrow Transplant
10. All Chronic Diarrhea
11. Zollinger – Ellison Syndrome
12. Thymoma/ Advanced Thymic Malignancy
13. Sulfonylurea – induced hypoglycemia
14. Malignant Bowel Obstruction
15. Hepatorenal Syndrome
16. Gastroesophageal variceal hemorrhage
17. Gastro –Entero- Pancreatic neuroendocrine tumors[metastic]
18. Acromegaly
19. Hypothalamic Obesity

Acromegaly
Sub or I.V
50ug TID
Up to 100ug TID
Maximum range is 300ug to 1500ug/day
Have med stopped for 4/52 every one year
Check GH, IGF[Insulin-like Growth factor 1]
Switching to Depot from SubQ:
Stability on SubQ x 2/52, then
Switch to the Depot
Give 20mg l.M. q 4/52 x 3/12
Review your parameters if the GH is less than or equal to 1ng/ml
IGF – 1 i.e. insulin, like growth factor-1 is normal,
then reduce Octreotide to 10mg I.M q 4/52
Titrate the dose based on GH and IGF – 1 levels

e.g. if GH is greater than 2.5ng/ml and IGF – 1 is elevated, then increase octreotide to 30mg I.M q4/52

If you have used maximum octreotide and not winning, add Pegvisomant [growth hormone receptor antagonist] or a Dopamine agonist
Carcinoid Crisis (Intra-operatively)
With hypotension
I.V. 500 to 1000ug bolus
Repeat at 5 minute intervals
Until symptoms are controlled
OR the bolus to be followed by 50-200ug per hour continuous infusion during the procedure
AND MANY MORE FACTS,ENJOY LISTENING!

Octreotide is a artificial peptide that copies the activity of somatostatin, a hormonal agent made through the hypothalamus. Somatostatin hinders the release of growth hormonal agent coming from the pituitary glandular and manages the secretion of other hormonal agents, including the hormone insulin and glucagon. Octreotide is used to deal with a range of problems, including acromegaly, carcinoid syndrome, and gastroenteropancreatic neuroendocrine growths.

One possible edge impact of octreotide therapy is body weight reduction. In some patients, this can easily be a desirable end result, specifically if they are overweight or obese. However, in others it may be challenging and...


"The Science Behind Octreotide and Its Effects on Weight" for Beginners



Octreotide is a artificial peptide that copies the activity of somatostatin, a hormonal agent made through the hypothalamus. Somatostatin hinders the release of growth hormonal agent coming from the pituitary glandular and manages the secretion of other hormonal agents, including the hormone insulin and glucagon. Octreotide is used to deal with a range of problems, including acromegaly, carcinoid syndrome, and gastroenteropancreatic neuroendocrine growths.

One possible edge impact of octreotide therapy is body weight reduction. In some patients, this can easily be a desirable end result, specifically if they are overweight or obese. However, in others it may be challenging and require assistance.

The mechanism through which octreotide causes weight loss is not entirely clear. One probability is that it lowers hunger through decreasing ghrelin secretion. Ghrelin is a hormone produced in the stomach that boosts hunger and food items consumption. Studies have presented that octreotide can minimize ghrelin degrees in healthy and balanced volunteers and in patients along with acromegaly or style 2 diabetic issues mellitus.

One more potential device for octreotide-induced weight loss is change of blood sugar metabolism. Octreotide has been presented to enhance blood insulin sensitivity in clients with kind 2 diabetes mellitus by decreasing hepatic glucose development and enhancing outer blood sugar uptake. This impact might additionally contribute to weight reduction by minimizing spreading sugar amounts and advertising fat oxidation.

In addition to these metabolic impacts, octreotide may possess direct effects on adipose tissue physiology. In vitro studies have presented that somatostatin receptors are present on adipocytes (fatty tissue cells) and that somatostatin can prevent lipolysis (the break down of saved fat). It is possible that octreotide has actually comparable results on adipose cells metabolic rate in vivo.

Professional studies have illustrated the effectiveness of octreotide for weight loss in various patient populaces. For example, a randomized controlled trial published in JAMA in 2008 matched up the effects of octreotide and inactive medicine on body weight loss in overweight grownups along with type 2 diabetes mellitus mellitus. After 16 weeks of therapy, the octreotide group shed an standard of 4.4 kilograms (9.7 lbs) matched up to a nasty weight increase of 0.5 kg (1.1 lbs) in the inactive medicine team.

An additional research study released in the Journal of Clinical Endocrinology and Metabolism in 2013 analyzed the results of octreotide on physical body body weight and make-up in clients along with acromegaly. After six months of procedure, individuals experienced substantial decreases in body weight, body mass index, and waistline circumference.

While octreotide can easily be helpful for weight reduction, it is not without risks and edge effects. Usual edge effects feature intestinal disturbances such as nausea or vomiting, diarrhea, and stomach pain. Unusual but serious side effects feature gallstones, pancreatitis, and heart arrhythmias.

In conclusion, octreotide is a man-made peptide that imitates the activity of somatostatin and has actually a range of therapeutic usage. One prospective side impact is body weight loss, which may be mediated by alterations in appetite guideline, glucose metabolic process, and adipose tissue anatomy. While successful for some clients, it is important to meticulously consider the risks and advantages just before initiating treatment along with octreotide for body weight loss functions.

Octreotide is a synthetic peptide that imitates the action of somatostatin, a hormone produced through the hypoth...

Susan Samson, MD, PhD, of Baylor College of Medicine talks about the recently approved Mycapssa (octreotide) capsules as long-term maintenance therapy for people with acromegaly.

Mycapssa is the only oral form of octreotide, a somatostatin analog, approved by the US Food and Drug Administration (FDA) to treat acromegaly.

Acromegaly is a rare endocrine disorder usually caused by a benign pituitary tumor and is characterized by excess production of growth hormone and insulin-like growth factor-1 hormone.

As Dr. Samson explains in this interview, the approval was largely based on the pivotal phase 3 CHIASMA OPTIMAL clinical trial showing Mycapssa to be superior to placebo in the randomized, double-blind, placebo-controlled, nine-month study.

The most common adverse events observed with Mycapssa were: cholelithiasis and complications of cholelithiasis; hyperglycemia and hypoglycemia; thyroid function abnormalities; cardiac function abnormalities; and decreased vitamin B12 levels and abnormal Schilling’s tests.

Patient Day 2014

octreotide - Indications, Dosage, Side Effects and Precautions
The Official Guide to octreotide - Indications, Dosage, Side Effects and Precautions