Dangerous Side Effects

Pharmacology of Midodrine; Definition, Mechanism of action, Pharmacokinetics, Uses, Effect
Pharmacology of Midodrine; Definition, Mechanism of action, Pharmacokinetics, Uses, Effect Side Effects 1 Views • 2 months ago

🧠 Midodrine Pharmacology Overview

Midodrine is a prodrug alpha-1 adrenergic agonist used primarily to treat symptomatic orthostatic hypotension (OH)—a condition where blood pressure drops upon standing, causing dizziness or fainting. It’s marketed under names like ProAmatine and Orvaten.

⚡ Mechanism of Action
Prodrug activation: Midodrine is converted to desglymidodrine, its active metabolite.

Alpha-1 receptor agonism: Desglymidodrine stimulates arteriolar and venous alpha-1 receptors, increasing vascular tone and blood pressure.

Peripheral selectivity: Minimal central nervous system penetration due to poor blood-brain barrier diffusion.

💊 Pharmacokinetics
Parameter Value
Bioavailability ~93% (as desglymidodrine)
Peak plasma time Midodrine: ~30 min; Desglymidodrine: ~1–2 hrs
Half-life Midodrine: ~25 min; Desglymidodrine: ~3–4 hrs
Excretion ~80% via urine (active renal secretion)
Metabolism Deglycination in tissues and liver
🧬 Pharmacodynamics
Blood pressure elevation: Increases standing systolic BP by ~15–30 mmHg within 1 hour of a 10 mg dose.

Duration: Effects persist for 2–3 hours.

No significant effect on heart rate or cardiac beta receptors.

💊 Therapeutic Uses
Indication Role of Midodrine
Orthostatic hypotension First-line treatment
Refractory ascites (off-label) Adjunct to diuretics
Hepatorenal syndrome (off-label) Combined with octreotide & albumin
Vasovagal syncope (off-label) Symptom reduction
Dialysis-induced hypotension Pre-dialysis BP support
⚠️ Safety & Side Effects
Common: Paresthesia, piloerection, chills, urinary retention, scalp itching.

Serious:

Supine hypertension (BP Greater than 200 mmHg)—monitor closely3

Bradycardia, especially with other heart rate-lowering drugs

Urinary retention

Contraindications: Pheochromocytoma, thyrotoxicosis, acute renal disease, severe heart disease

🧪 Chemical Profile
Property Value
Molecular Formula C₁₂H₁₈N₂O₄
Molecular Weight 254.28 g/mol
Drug Class Alpha-1 adrenergic agonist (prodrug)
Structure Type Ethanolamine derivative

#Midodrine

Tablet For Low Blood Pressure In Hindi | Midodrine Hydrochloride Gutron 2.5 mg
Tablet For Low Blood Pressure In Hindi | Midodrine Hydrochloride Gutron 2.5 mg Side Effects 1 Views • 2 months ago

tablet for blood pressure in hindi midodrine hydrochloride gutron 2.5 mg

Hi passi champ family 👋
Is video ke episode low blood pressure ko treat karne ke liye best tablet ka review diya hai. Is video main maine gutron 2.5 mg jis main midodrine hydrochloride 2.5 mg composition hai iske bare main btaya hai jaise iske price rate, company, uses, how to take, dosage or side effects ka ache se explain kiya hai. labialfarma iski manufacturer hai or gurmail brothers iski marketing krte hai. Yeh low blood pressure ko treat karne ke liye india main best medicines main se ek hai.
#midodrine #gutron2.5mg #tabletforlowbloodpressure
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Doctor explains METOPROLOL (Lopressor) | Uses, Doses, side effects & more [Educational video]
Doctor explains METOPROLOL (Lopressor) | Uses, Doses, side effects & more [Educational video] Side Effects 1 Views • 2 months ago

In this video Doctor O'Donovan explains key facts you need to know about Metoprolol - also known by its brand name 'Lopressor' - a medication used to treat high blood pressure (hypertension), heart problems and migraine.

What is Metoprolol?

Metoprolol is a type of medicine called a beta blocker. Like other beta blockers, metoprolol works by changing the way your body responds to some nerve impulses, especially in the heart. It slows down your heart rate and makes it easier for your heart to pump blood around your body.

What doses of Metoprolol / Tablet Strengths and Uses are available?

Metoprolol is available in 50mg and 100mg strengths, used for treating high blood pressure, chest pain, irregular heartbeat, migraine prevention, and thyrotoxicosis, with varying dosages specific to each condition.

Administration Guidelines

Metoprolol an be taken with or without food, tablets should be swallowed whole with water, and some can be split in half if indicated. The first dose might be recommended at bedtime due to possible dizziness, otherwise taken in the morning, with evenly spaced doses if multiple are required daily.

Duration and Discontinuation

Metoprolol treatment is typically long-term, potentially lifelong. Stopping abruptly can worsen the condition, so a doctor's guidance is needed for cessation. The medicine takes 1 to 2 days to leave the body after stopping.

Overdose Risks and Actions

Overdose effects vary but can include slowed heart rate, breathing difficulties, dizziness, and trembling. Immediate medical advice is necessary if an overdose occurs. Bring medication packet and any remaining pills to the emergency services.

Are there any side effects of metoprolol?

According to the NHS UK website "Metoprolol is generally safe to take for a long time. In fact, it works best when taken for long periods of time."

********************************************************************

Content and timestamps:

00:00 - Introduction
01:03 - Who can and can't take metoprolol (lopressor)
01:57 - How and when to take metoprolol
05:04 - Side effects
06:50 - Interactions with other medications
08:33 - Common questions

***************************************************************************

References and resources

NHS information:
https://www.nhs.uk/medicines/metoprolol/

WebMD: https://www.webmd.com/drugs/2/....drug-8814-2372/metop

National Institute for Clinical Excellence (NICE UK): https://bnf.nice.org.uk/drugs/metoprolol-tartrate/

#doctor #health #medication #pharmacy #lopressor #metoprolol #betablocker #bloodpressure #highbloodpressure #hypertension

Video published: 1st April 2024. Next review: 2027.
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The video is intended as an educational resource only. The information within this video or on this channel isn't designed to replace professional input, so if you have any medical issues please consult a medical provider. No professional relationship is being created by watching this video. Dr. O'Donovan cannot give any individual medical advice. All information should be verified for accuracy by the individual user. Dr O'Donovan accepts no responsibility for individual interpretation of data, although it is always accurate to the best of his knowledge at the time of the video being published. This is an EDUCATIONAL video. Images are used in accordance with fair use guidelines.

Legal information:

Content provided via YouTube is for general information purposes ONLY. Information videos are not produced to provide individualised medical advice. Medical education videos on Doctor O'Donovan are not a substitute for professional professional medical advice, diagnosis or treatment. NEVER ignore professional medical advice because of something you have heard here. ALWAYS consult your doctor regarding any concerns about your condition or treatment.

Midodrine in the ICU: Saving Lives Podcast
Midodrine in the ICU: Saving Lives Podcast Side Effects 1 Views • 2 months ago

Ever have a patient who is on low dose norepinephrine or another vasopressor who you can't get out of the ICU solely for that reason? Have you tried to administer midodrine to increase their blood pressure? This podcast describes the FDA-approved as well as the off-label uses of midodrine, pharmacology data explained in english, dosing, side effects, and a little about the studies. I discuss the mechanism of action, midodrine uses, midodrine parameters, what's comparable to a midodrine IV drip or midodrine drip, the brand name, and more!

Show Notes:
https://eddyjoemd.com/midodrine/

The Vasopressor & Inotrope Handbook
I have written "The Vasopressor & Inotrope Handbook: A Practical Guide for Healthcare Professionals," a must-read for anyone caring for critically ill patients (check out the reviews)! You have several options to get a physical copy.
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Although great care has been taken to ensure that the information in this post is accurate, eddyjoemd, LLC shall not be held responsible or in any way liable for the continued accuracy of the information, or for any errors, omissions or inaccuracies, or for any consequences arising therefrom.

Midodrine for POTS
Midodrine for POTS Side Effects 1 Views • 2 months ago

A full transcript is available at https://drsanjayguptacardiolog....ist.com/blog/midodri
POTS is characterised by orthostatic intolerance. This means that patients feel significantly worse when they adopt an upright posture compared to when they are lying down. To try and find effective treatments, it is vital that we try and understand the physiology of what happens in the body when normal healthy people stand up.

When we stand up, blood in our vessels tends to get sucked down into our legs because of the effect of gravity. This means that there is less blood getting to our brain and ordinarily we would all pass out and fall because of a shortage of blood to the brain. This does not happen because two reflex mechanisms come into action which serve to maintain the blood flow to our brains. The first is regulated by stretch receptors in our blood vessels in the legs which try and constrict the best they can to prevent blood from pooling in the legs. Secondly the heart rate increases to try and maintain adequate blood flow to the brain. In some patients, the leg vessels don’t constrict as well and therefore they are not able to contribute to increasing the blood flow to the brain and therefore the body has to compensate for this by increasing the heart rate even further. As the heart rate goes up excessively the heart doesn’t have as much time to fill with blood and therefore pumps out less blood than it should which exacerbates the situation.

If we can in some way reduce the stretching of blood vessels especially in the lower limbs when we adopt an upright posture, it means that there is relatively more blood going round and less blood pooling which can improve symptoms.

Midodrine works by increasing the tone of our peripheral blood vessels and therefore reduces the likelihood of pooling of blood. It doesn’t really directly affect the heart as such but if there is more blood getting to the heart then that means that every heart beat is more effective and that can have the effect of improving orthostatic tolerance. Interestingly though this can also have an unwanted effect on the bladder. Because of the effect of the agent on tone, the bladder does not stretch as much and therefore bladder emptying is delayed.

Benzodiazepines - Mechanism of action, Clinical Use & Side Effects
Benzodiazepines - Mechanism of action, Clinical Use & Side Effects Side Effects 1 Views • 2 months ago

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http://usmlefasttrack.com/?p=1894 Benzodiazepines, Mechanism, of, action, Clinical, Use, Side, Effects, diazepam, lorazepam, triazolam, temazepam, oxazepam, midazolam, chlordiazepoxide, alprazolam, frequency, decrease rem sleep, spasticity, status epilepticus, detoxification, flumazenil, antagonist, ligand-gated, chloride, neurology, Pharmacology, , symptoms, findings, causes, mnemonics, review, what is, video, study, Rapid Review, Clinical presenation, First Aid, for, USMLE, Step 1, images, wiki, define, wikipedia, 2013, videos, exam, prep, easy, What is usmle, mnemonic, causes,

2-Minute Neuroscience: Benzodiazepines
2-Minute Neuroscience: Benzodiazepines Side Effects 1 Views • 2 months ago

Benzodiazepines are commonly used to treat anxiety disorders and sleep disorders. They are thought to exert their effects in the brain by acting at receptors for the neurotransmitter gamma-aminobutyric acid, or GABA. In this video, I cover the the mechanism of action for benzodiazepines.

TRANSCRIPT:

Welcome to 2 minute neuroscience, where I explain neuroscience topics in 2 minutes or less. In this installment I will discuss benzodiazepines.

Benzodiazepines are a class of drugs named for their chemical structure that are commonly used to treat anxiety disorders and sleep-related disorders. They include well-known drugs like valium, xanax, and klonopin. There are dozens of drugs in the benzodiazepine class, but the mechanism by which they all exert their effects is thought to be similar.

The sedating and anxiety-reducing effects of benzodiazepines are believed to be attributable to the drugs’ actions at receptors for the neurotransmitter gamma-aminobutyic acid, or GABA. In particular, benzodiazepines act at a subtype of GABA receptors called the GABAa receptor; GABAa receptors that also bind benzodiazepines are sometimes called benzodiazepine receptors.

When benzodiazepines bind, or attach, to the GABA receptor, they bind at a location separate from where GABA itself binds, and exert an influence over GABA binding. This type of action is called an allosteric effect, and in the case of benzodiazepines it results in increased action at the GABA receptor. There is not complete consensus on exactly how benzodiazepine binding affects activity at the GABA receptor but there is evidence to suggest that it increases the likelihood that GABA binding will activate the receptor and/or increases the effect that GABA has when it binds to the receptor.

That effect is to open an ion channel and allow the passage of negatively charged chloride ions into the neuron. This influx of negatively charged ions pushes the membrane potential further from zero, or hyperpolarizes it, and makes it less likely the neuron will fire an action potential. This type of neural inhibition is the basis for the effects of benzodiazepines, for by inhibiting the activity of neurons that make up networks involved with anxiety and arousal, the drugs are able to produce calming effects.


REFERENCES:

Gielen MC, Lumb MJ, Smart TG. Benzodiazepines modulate GABAA receptors by regulating the preactivation step after GABA binding. J Neurosci. 2012 Apr 25;32(17):5707-15. doi: 10.1523/JNEUROSCI.5663-11.2012.

Möhler H, Fritschy JM, Rudolph U. A new benzodiazepine pharmacology. J Pharmacol Exp Ther. 2002 Jan;300(1):2-8.

Midazolam (Versed) - Critical Care Medications
Midazolam (Versed) - Critical Care Medications Side Effects 1 Views • 2 months ago

A medication review focused on Midazolam (Versed).

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0:00 Intro
1:54 History and Therapeutic Actions
3:06 Indications/Contraindications
4:01 Adverse Effects
4:46 Concentrations/Dosing/Pharmacokinetics
7:27 Nursing considerations
8:47 Wrap Up

#ICUAdvantage #Midazolam #Medications

MIDAZOLAM (VERSED) - PHARMACIST REVIEW - #76
MIDAZOLAM (VERSED) - PHARMACIST REVIEW - #76 Side Effects 1 Views • 2 months ago

In this episode, I discuss a medication known as midazolam (Versed, Seizalam).

My book is now available! It discusses my experience with Bipolar Disorder.
The Fifth Episode - Inside The Manic Mind.
Find it here:

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EMT/Paramedic Medication Notecards || Midazolam
EMT/Paramedic Medication Notecards || Midazolam Side Effects 1 Views • 2 months ago

Thanks for watching the video Versed in EMS!

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DISCLAIMER: The information in this video is not intended to be a replacement for professional medical advice. ALWAYS follow YOUR local protocol and scope of practice!

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EMS Cardiology || Tachy Tuesday: Ventricular Triplets in EMS
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Chit Chat w/ the Combat Midwife || Treating Mind, Body and Soul
https://youtu.be/XWUtwAZXq08

EMT/Paramedic Medication Notecards || Atropine Sulfate (Updated ACLS 2020)
https://youtu.be/kxO1cAJs350

Strokes in EMS || Recognition is key!
https://youtu.be/ynxN13lbiM8

How to Write a Stroke Narrative in EMS || Stroke DCHART Made Easy! (Example Included)
https://youtu.be/7Iwyiw2EbBw

EMT/Paramedic Mnemonics || AEIOU-TIPS
https://youtu.be/Xgwqr9fS0xQ

BIG EMS MISTAKES!! || HOW TO HANDLE WHEN YOU MESS UP IN EMS
https://youtu.be/MU1lOR2RTXo

WHY I TOOK ALL MY PREVIOUS VIDEOS DOWN || HARD TO ADMIT!
https://youtu.be/snuOnUr8Yv8

EMS Q&A || WHAT SHOULD I STUDY TO PASS THE NREMT? HARDEST PART OF EMS? MANAGEMENT OF DKA?
https://youtu.be/2Dzce9Mue2k

HOW TO ROCK YOUR PARAMEDIC INTERNSHIP | TOP TIPS FOR SUCCESS
https://youtu.be/AhA01_S5Oho

EMS IV INSERTION EXAMPLE || EMS SKILLS
https://youtu.be/2tN8D7GAS6A

DIFFERENT EMS CAREERS | 30 WAYS TO USE YOUR EMS LICENSE
https://youtu.be/p-mLtUx2KUM

WHAT I WISH I WOULD HAVE K.tNOWN BEFORE I WENT INTO EMS || LOSING FRIENDS
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Buccolam (Midazolam)
Buccolam (Midazolam) Side Effects 1 Views • 2 months ago

Buccolam pre-filled oral syringes contain the active ingredient midazolam, which is a type of medicine called a benzodiazepine.

If you would like to find out more visit: 
http://www.lynchspharmacy.com/medicine/buccolam
http://www.lynchspharmacy.com

You can also visit Lynch's Pharmacy in Broadale, Maryborough Hill, Cork.

Please note that this video is meant for educational purposes only, and should not be used as a means to diagnose any health condition. You should always consult your doctor if you have any concerns regarding your health or medication.We are not selling or advertising any product our videos include.

Thank you for watching!

Midazolam (Versed) - Uses, Dosing, Side Effects
Midazolam (Versed) - Uses, Dosing, Side Effects Side Effects 1 Views • 2 months ago

In this episode, I discuss a medication known as midazolam (Versed, Seizalam).

My book is now available! It discusses my experience with Bipolar Disorder.
The Fifth Episode - Inside The Manic Mind.
Find it here:

BookBaby (best way to support this project):
https://store.bookbaby.com/book/the-fifth-episode

Amazon:
https://www.amazon.com/Fifth-Episode-Inside-Manic-Mind/dp/1667843451/ref=sr_1_12?crid=26PVK90TTXRBO&keywords=the+fifth+episode+paperback&qid=1654191898&sprefix=the+fifth+episode+paperback%2Caps%2C61&sr=8-12

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Support the channel on Patreon:
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Group-2 BP Tablets | Beta Blocker | Metoprolol Tablet | Control BP | Dr. Ravikanth Kongara
Group-2 BP Tablets | Beta Blocker | Metoprolol Tablet | Control BP | Dr. Ravikanth Kongara Side Effects 1 Views • 2 months ago

Group-2 BP Tablets | Beta Blocker | Metoprolol Tablet | Control BP | Dr. Ravikanth Kongara

--*****--
గత 12 సంవత్సరాలుగా రెండు తెలుగు రాష్ట్రాల ప్రజలకి అత్యాధునిక ప్రమాణాలతో సరికొత్త ఆధునిక వైద్య సేవలని డాక్టర్ కొంగర రవికాంత్ గారు అందిస్తున్నారు. విజయవాడలోని వారి కర్పోరేట్ స్థాయి హాస్పటల్లో తమ విశేష అనుభవంతో సామాన్యులకి కూడా అందుబాటులో ఉండే నాణ్యమైన వైద్య సేవలు అందిస్తూ గొప్ప పేరు సాదించారు.

అన్ని రకాల గ్యాస్ట్రో, బేరియాట్రిక్ సర్జరీ, లాపరోస్కోపీ సమస్యలకి చికిత్స అందిస్తూ దక్షిణ భారతదేశంలోనే నెలకు అత్యధిక బేరియాట్రిక్ సర్జరీలు చేస్తు గొప్ప ఫలితాలు సాదించారు. అంతేగాక 200 నుండి 250 కిలోల కంటే ఎక్కువ బరువున్న అత్యంత ప్రమాదకర బేరియాట్రిక్ సమస్యకి శస్త్రచికిత్స చేసి అసాధ్యాన్ని సుసాధ్యం చేసారు. సుమారు 200 కిలోల కంటే ఎక్కువ బరువున్న సూపర్ ఒబేసిటీ పేషెంట్లు మంచి ఫలితాలని పొందారు.

విజయవాడలో మొట్ట మొదటిసారిగా విదేశి తరహాలో అత్యాధునిక సౌకర్యాలతో 24 గంటలు వైద్యుల పర్యావేక్షణలో వైద్య సేవలు అందిస్తున్నారు. 100 పడకలతో పాటు అత్యవసర సమయంలో ఆంబులెన్స్ సౌకర్యం కలదు.

Dr. Ravikanth Kongara MBBS, MS, DNB(Gastro-NIMS)
Ravi Hospital, Bariatric, gastro, laparoscopy, Swathi Press - opp Kovelamudi Street, Suryaraopeta, Vijayawada - 2, Andhra Pradesh: 520002, Phone: 0888 183 8888, 888 184 8888.
https://g.co/kgs/XJHvYA

Health Disclaimer:
___________________
The Information in this Video is Designed for EDUCATIONAL Purpose Only. It is not intended to be a substitute for informed medical advice or care. You Should not use this information to diagnose or treat any health problems. Please consult a doctor with any questions or concerns you might have regarding your or your child's condition.

#BP #BetaBlocker #MetoprololTablet #DrRaviHospital #DrRavikanthKongara

Metoclopramide Pharmacology
Metoclopramide Pharmacology Side Effects 1 Views • 2 months ago

An overview of Metoclopramide pharmacology. Check out more FOAMed videos at www.paramedicresource.ca

References:

Pathan H, Williams J. Basic opioid pharmacology: an update. British Journal of Pain. 2012;6(1):11-16. doi:10.1177/2049463712438493.

What is Reglan used for? Common uses, dosing details, potential side effects, and user experiences
What is Reglan used for? Common uses, dosing details, potential side effects, and user experiences Side Effects 1 Views • 2 months ago

Reglan, also known by its generic name metoclopramide, is a medication that is primarily used to treat gastrointestinal disorders. It works by increasing the movement and contractions of the stomach and intestines, which helps to improve the symptoms associated with certain conditions.

One of the main uses of Reglan is to treat gastroesophageal reflux disease (GERD). GERD is a chronic condition where stomach acid flows back into the esophagus, causing symptoms like heartburn, acid regurgitation, and difficulty swallowing. By enhancing the movement of the digestive system, Reglan can help reduce these symptoms and provide relief to patients.

Another common use of Reglan is for the treatment of diabetic gastroparesis. Gastroparesis is a condition where the stomach takes longer than usual to empty its contents, leading to symptoms like nausea, vomiting, and bloating. In patients with diabetes, high blood sugar levels can damage the nerves that control stomach contractions, resulting in gastroparesis. Reglan can help improve the motility of the stomach and alleviate these symptoms.

Reglan is also sometimes prescribed to individuals undergoing chemotherapy or radiation therapy to prevent or relieve nausea and vomiting caused by these treatments. It works by blocking certain receptors in the brain that trigger these symptoms, offering much-needed relief to patients who may already be dealing with the side effects of cancer treatments.

It's important to note that Reglan should only be used as directed by a healthcare professional and for the specific conditions it is prescribed for. Like any medication, Reglan can have potential side effects, and its use should be closely monitored by a healthcare provider.

In conclusion, Reglan is a medication commonly used to treat gastrointestinal disorders such as GERD, diabetic gastroparesis, and chemotherapy-induced nausea and vomiting. Its ability to enhance stomach and intestinal contractions makes it an effective option for managing symptoms associated with these conditions."
-----
"DISCLAIMER: The content of this video is for informational and educational purposes only. It should not be used as a substitute for medical consultation. You should always seek the advice of your doctor or healthcare professional before taking any medication or starting any treatment. Treatments and medications should be prescribed and supervised by a qualified medical doctor only. Individual results may vary and the effectiveness of any treatment mentioned in this video is not guaranteed. Do not self-medicate, if you have any health problems, it is important to seek medical help immediately."

Can Metoclopramide Help With Migraines? - Oncology Support Network
Can Metoclopramide Help With Migraines? - Oncology Support Network Side Effects 1 Views • 2 months ago

Can Metoclopramide Help With Migraines? Migraines can be debilitating, affecting daily activities and overall quality of life. In this informative video, we will discuss the medication Metoclopramide and its potential role in managing migraine symptoms. We will outline how Metoclopramide is primarily used for treating nausea and vomiting, and explore its effectiveness when addressing migraine-related discomfort.

You will learn about the mechanism of action of Metoclopramide and how it may help alleviate some of the distressing symptoms that often accompany migraines. We will also touch upon the importance of understanding both the benefits and risks associated with this medication, including possible side effects that may arise from its use.

If you are considering Metoclopramide for migraine relief, it’s essential to consult with a healthcare professional who can offer tailored guidance based on your health history and specific needs. This video aims to provide you with the information necessary to make informed decisions about your migraine management options.

Join us for this essential discussion, and don’t forget to subscribe to our channel for more helpful content on managing migraines and other health-related topics.

⬇️ Subscribe to our channel for more valuable insights.

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#Metoclopramide #Migraines #MigraineRelief #HeadacheTreatment #NauseaRelief #PainManagement #HealthcareAdvice #MedicationGuide #MigraineAwareness #ChronicPain #HealthTips #Pharmacy #PatientEducation #MigraineSupport #WellnessJourney

About Us: Welcome to the Oncology Support Network, your trusted source for comprehensive information and support in the field of oncology. Our channel is dedicated to empowering patients, caregivers, and healthcare professionals with the latest insights on cancer treatment, research breakthroughs, and wellness strategies. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Metoclopramide (Plasil): Mechanism of Action, Therapeutic Uses & Adverse Effects
Metoclopramide (Plasil): Mechanism of Action, Therapeutic Uses & Adverse Effects Side Effects 1 Views • 2 months ago

in this video, I talk about Metoclopramide, topics covered include:
- Mechanism of action
- Therapeutic uses
- Adverse effects
- Drug- Drug interactions
- Contraindications
=============================
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**** Picture used in the thumbnail is licensed under creative commons licensing, credit: Intropin (Mark Oniffrey), CC BY-SA 4.0 https://creativecommons.org/licenses/by-sa/4.0, via Wikimedia Commons
=============================
Video Chapters
0:00 Introduction
0:21 Mechanism of action
4:07 Therapeutic uses
6:45 Pharmacokinetics
7:58 Adverse effects
12:57 Drug- Drug interactions
15:00 Contraindications

METOCLOPRAMIDE - - Generic Name, Drug class, Brande Name ,Precautions ,  How to use,  Side Effects
METOCLOPRAMIDE - - Generic Name, Drug class, Brande Name ,Precautions , How to use, Side Effects Side Effects 1 Views • 2 months ago

#medicalknowledgeonline ,
Generic Name,Drug class, Brande Name
What is AMPICILLIN ? , 1:00
Vital information, 2:00
Before taking this medicine (Precautions ), 3:39
How to use , 5:07
Dosage info - 7:15
Miss a dose, 7:55 Overdose , 8:13
Stop or Avoid Taking , 8:23
Side Effects, 8:37
Other Drugs Will Affect, 10:20
- Generic Name, Drug class, Brande Name ,Precautions , How to use, Side Effects
#medicalknowledgeonline

TOPICS
1. ANATOMY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
2. PHYSIOLOGY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
3. DISEASES – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
4. PUBLIC HEALTH- Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
5. Rx – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
6. LABORATORY TEST – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
7. MEDICAL IMAGING – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
8. SURGICAL AND MEDICAL PROCEDURES – topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
9. MICROBIOLOGY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
10. BIOCHEMISTRY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
11. NUTRITION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
12. HEALTH TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
13. MEDICAL & SURGICAL – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
14. PAEDIATRICS / CHILD HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
15. MENTAL HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
16. MATERNAL HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
17. COMMUNITY HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
18. NURSING FOUNDATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
19. BIOSTATISTICS – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
20. PATHOLOGY – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
21. NURSING EDUCATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
22. HOSPITAL MANAGEMENT AND HEALTH CARE ADMINISTRATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
23. NURSING RESEARCH – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
24. NURSING FOUNDATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
25. PHARMACOLOGY – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
26. PUBLIC HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
27. INTERNATIONAL DAYS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
28. NURSING - TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
#medicalknowledgeonline

Metoclopramide Mechanism and Side Effects
Metoclopramide Mechanism and Side Effects Side Effects 1 Views • 2 months ago

Metoclopramide is a medication that belongs to a class of drugs known as prokinetic agents. It's primarily used to treat gastrointestinal issues such as nausea, vomiting, and certain digestive disorders. Metoclopramide works by increasing the movement of the stomach and intestines, which can help improve the passage of food and fluids through the digestive system.

Here are some key points about metoclopramide:

Indications:
1. Nausea and Vomiting: Metoclopramide is commonly prescribed to alleviate nausea and vomiting associated with various conditions, including chemotherapy-induced nausea, postoperative nausea, and migraines.
2. Gastroesophageal Reflux Disease (GERD): It can be used to treat symptoms of GERD, such as heartburn and regurgitation.
3. Digestive Disorders: Metoclopramide may be prescribed for certain gastrointestinal disorders like gastroparesis, which is a condition where the stomach doesn't empty properly.

Mechanism of Action:
Metoclopramide acts by blocking dopamine receptors in the brain and peripheral nervous system. This action helps to increase the contractions of the muscles in the stomach and intestines, thus promoting the movement of food and reducing the symptoms of nausea and vomiting.

Administration:
The medication is available in various forms, including oral tablets, oral solution, and injectable forms. The dosage and administration depend on the specific condition being treated and the patient's age and medical history.

Side Effects:
Common side effects of metoclopramide may include drowsiness, restlessness, fatigue, headache, and diarrhea. In some cases, it can also cause more serious side effects, such as involuntary muscle movements (tardive dyskinesia) if used for extended periods. Tardive dyskinesia involves repetitive, uncontrollable movements of the face, tongue, or other body parts.

Precautions and Contraindications:
- Metoclopramide should be used with caution in patients with a history of movement disorders, as it may worsen these conditions.
- It should be avoided or used with caution in patients with a history of seizure disorders, as it can lower the seizure threshold.
- The medication is generally not recommended during pregnancy unless the benefits clearly outweigh the risks.

Drug Interactions:
Metoclopramide can interact with other medications, potentially affecting their effectiveness or causing adverse effects. It's important to inform your healthcare provider about all the medications you're taking before starting metoclopramide.

Important Note:
This information is based on general knowledge up until September 2021. Always consult a healthcare professional or a pharmacist for the most up-to-date and accurate information about medications, including metoclopramide.

Prednisone for MS  3 Treatment Avenues Explained!
Prednisone for MS 3 Treatment Avenues Explained! Side Effects 1 Views • 2 months ago

Sign up for the Monthly "Boster Corner" Newsletter: https://bosterms.com/get-boster-news/

The Boster Center for Multiple Sclerosis accepts new consultations and is actively enrolling several MS clinical trials! www.BosterMS.com or call 614-304-3444 to schedule!

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NOTE: Make sure to talk to your provider before ANY treatment decision. We hope to educate, empower and energize those impacted by Multiple Sclerosis. This channel consists of a collection of formal lectures and informal video clips about MS to help educate others. These videos do not provide medical advice and are for informational/educational purposes only. The videos are not intended to be a substitute for professional medical advice, diagnosis or treatment. Always seek the advice of a qualified health provider with any questions you may have regarding a medical condition. Never disregard professional medical advice or delay in seeking it because of something you have read or seen in any of our videos. They are just to help educate you about the condition guys!

How Does Methylprednisolone Work In The Body? - Pain Medicine Network
How Does Methylprednisolone Work In The Body? - Pain Medicine Network Side Effects 1 Views • 2 months ago

How Does Methylprednisolone Work In The Body? In this informative video, we will explore the role of methylprednisolone in pain management and how it interacts with the body. Methylprednisolone is a synthetic corticosteroid known for its ability to manage inflammation, which is often a primary factor in various painful conditions. We will discuss the mechanisms through which this medication operates, including its effects on gene expression and immune responses.

You’ll learn how methylprednisolone influences immune cells and the significance of its action at both cellular and systemic levels. Additionally, we will cover the various applications of methylprednisolone in treating acute and chronic inflammatory conditions, including its use in joint injections and post-surgical recovery.

Understanding the onset of its effects and the different methods of administration will also be highlighted. While methylprednisolone is effective, it’s essential to recognize that it is not a direct pain reliever but rather works by addressing the underlying causes of pain. Consulting with a healthcare professional is vital to determine if this medication is suitable for your specific needs.

Join us for this engaging discussion, and subscribe to our channel for more helpful information on pain medicine and management.

⬇️ Subscribe to our channel for more valuable insights.

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#Methylprednisolone #PainManagement #Corticosteroids #Inflammation #PainRelief #ChronicPain #AcutePain #JointPain #RheumatoidArthritis #PolymyalgiaRheumatica #ImmuneResponse #MedicalAdvice #Healthcare #PainControl #MedicationManagement

About Us: Welcome to Pain Medicine Network, your trusted source for comprehensive information on pain management and treatment options. Our channel is dedicated to exploring the latest advancements in pain medicine, offering insights into innovative therapies, research breakthroughs, and expert interviews.
Please note that our content is purely informational and should not be considered medical advice. Always consult a healthcare professional for personalized guidance and do your own due diligence when it comes to your health and treatment options. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Betnesol tablet use / Betamethasone tablets ip 0.5 mg uses in hindi / Betnesol tablet
Betnesol tablet use / Betamethasone tablets ip 0.5 mg uses in hindi / Betnesol tablet Side Effects 1 Views • 2 months ago

Betnesol tablet use / Betamethasone tablets ip 0.5 mg uses in hindi / Betnesol tablet
#betnesoltablet #betamethasone #creativehealthcare

Betnesol tablet contains betamethasone which is a long acting corticosteroid medicine.
Betnesol tablet is used to treat allergic disorders inflammatory disorders and autoimmune disorders.
In this video we will discuss about:-
Betnesol tablet strengths
Betnesol tablet uses
Betnesol tablet mode of action
Betnesol tablet dosage
Betnesol tablet side effects
Betnesol tablet precautions
Betnesol tablet drug interactions.


#betnesoltablet #betamethasone #rheumatoidarthritis #asthma #betnesol #creativehealthcare #pharmacistdanish


Deflazacort tablets:-
https://youtu.be/9hcwDPG3OWk?si=-o-VBvevL-d68xqU

Dexamethasone tablets:-
https://youtu.be/C8pHWDmVxg4?si=CC1BpyPndY2CZ7DR

Methylprednisolone tablets:-
https://youtu.be/DfGU2KJV4Mw?si=O3pBVRZxRCRlZLV4

Mesalamine tablets:-
https://youtu.be/9DVb8dvvZ0k?si=Pmyiu7MwMIBHq9Uv

Sulfasalazine tablets:-
https://youtu.be/lWU-rq9rqf8?si=9MlZC1GBIixTRNn0

Febuxostat tablets:-
https://youtu.be/RmZcYiicJYM?si=TkI7cvmLMpgT3ltB

Cetirizine tablets:-
https://youtu.be/D1POSJsO3IQ?si=pIMRR2gp6dE7fjUZ

Montelukast levocetirizine tablets:-
https://youtu.be/_GK21sbQVec?si=yEj1DjeBycX333LB



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Disclaimer :- We create videos for education and information purpose only.Please consult your doctor before taking any medicine.we are not promoting self medication.This channel doesn't take any responsibility for any harm,side effect or any health problem caused due to the use of our content.

Starting Methotrexate for Rheumatoid Arthritis: RA Patients Share Their Experience Part 1
Starting Methotrexate for Rheumatoid Arthritis: RA Patients Share Their Experience Part 1 Side Effects 1 Views • 2 months ago

Methotrexate can be very effective for treating rheumatoid arthritis, but it’s normal for people to have concerns about starting it. We asked a group of people living with RA what it’s like to take methotrexate, how they cope with side effects, and more.

Watch part two here:
https://youtu.be/h8Cu45w-3yw

This video features the perspectives of other patients. This is not medical advice and should not take the place of professional medical care.

This video is part of an educational project from researchers at @yale, Berkshire Medical Center, @cmu, @HSpecialSurgery, CreakyJoints and the Global Healthy Living Foundation, and ArthritisPower.

It was made possible with support from the Rheumatology Research Foundation.

Learn more about the project at https://creakyjoints.org/rheum....atoid-arthritis-trea

--
About CreakyJoints
CreakyJoints® is a digital community for millions of arthritis patients and caregivers worldwide who seek education, support, advocacy, and patient-centered research. We represent patients in English and Spanish through our popular social media channels, our websites, and the 50-State Network, which includes more than 1,600 trained volunteer patient, caregiver, and health care activists. Learn more at https://creakyjoints.org/.

METHOTREXATE (OTREXUP) - PHARMACIST REVIEW - #236
METHOTREXATE (OTREXUP) - PHARMACIST REVIEW - #236 Side Effects 1 Views • 2 months ago

In this episode, I discuss a medication known as methotrexate (Otrexup, Rasuvo).

My book is now available! It discusses my experience with Bipolar Disorder.
The Fifth Episode - Inside The Manic Mind.
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How Does Methocarbamol (Robaxin) Work In The Body? - Pain Medicine Network
How Does Methocarbamol (Robaxin) Work In The Body? - Pain Medicine Network Side Effects 1 Views • 2 months ago

How Does Methocarbamol (Robaxin) Work In The Body? In this informative video, we will discuss Methocarbamol, commonly known by its brand name Robaxin, and its role in managing acute musculoskeletal pain. We’ll cover how this muscle relaxant operates within the body, focusing on its central action in the brain and spinal cord. You’ll learn about the mechanisms by which Methocarbamol reduces nerve activity, leading to muscle relaxation and a decrease in spasms.

We’ll also highlight the importance of using Methocarbamol appropriately, including its recommended short-term use for conditions like back pain and injury recovery. Additionally, we’ll touch on potential side effects and the significance of combining medication with non-pharmacological approaches for optimal pain management.

Whether you are considering Methocarbamol for your pain relief or simply want to understand more about muscle relaxants, this video provides essential information to help you navigate your options. Remember, it’s always best to consult with a healthcare provider for personalized advice regarding any medication you may be considering. Join us for this informative discussion, and subscribe to our channel for more helpful content on pain management and medicine.

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#Methocarbamol #Robaxin #MuscleRelaxants #PainManagement #MusculoskeletalPain #AcutePainRelief #SpinalCord #NerveActivity #Drowsiness #PhysicalTherapy #PainRelief #HealthcareAdvice #MedicationSafety #InjuryRecovery #PainReliefStrategies

About Us: Welcome to Pain Medicine Network, your trusted source for comprehensive information on pain management and treatment options. Our channel is dedicated to exploring the latest advancements in pain medicine, offering insights into innovative therapies, research breakthroughs, and expert interviews.
Please note that our content is purely informational and should not be considered medical advice. Always consult a healthcare professional for personalized guidance and do your own due diligence when it comes to your health and treatment options. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

Will Methocarbamol Help Sciatica? - Orthopedic Support Network
Will Methocarbamol Help Sciatica? - Orthopedic Support Network Side Effects 1 Views • 2 months ago

Will Methocarbamol Help Sciatica? Are you struggling with the discomfort of sciatica and looking for potential relief options? In this informative video, we will discuss methocarbamol, a muscle relaxant that has been used since the 1950s. We’ll explain how this medication works and its role in treating muscle spasms and acute musculoskeletal pain. You’ll learn about sciatica, a condition that causes pain in the lower back and legs due to irritation of the sciatic nerve, and how muscle spasms can play a part in this condition.

We’ll also review the effectiveness of methocarbamol in managing symptoms associated with sciatica, particularly in cases where muscle spasms are present. Additionally, we’ll touch on the importance of a multi-faceted treatment plan that can include other medications, rest, and physical therapy. Understanding potential side effects is also essential, so we’ll cover what to be aware of when considering methocarbamol as part of your treatment strategy.

Always consult with a healthcare professional to discuss whether methocarbamol is suitable for your specific situation. Join us for this informative discussion and subscribe to our channel for more helpful content on orthopedics and pain management.

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About Us: Welcome to the Orthopedic Support Network, your go-to resource for all things orthopedic! Our channel is dedicated to empowering individuals with information about orthopedic health, treatments, and innovations. Whether you're dealing with joint pain, recovering from surgery, or simply looking to enhance your physical well-being, we cover a range of topics including injury prevention, rehabilitation exercises, and expert interviews with leading orthopedic specialists. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

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