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- This is lesson n# 91 in "A DRUG IN BRIEF" Series. In this video I'm gonna discuss almost all you need to know about Clozapine ( Clozaril ): What is Clozapine? Clozaril Uses, Dose, Adverse Effects, Precautions and mechanism of action

- In 3 minutes you'll learn:

- What is Clozapine ( Clozaril ): What is Clozapine? Clozapine uses, Side effects of Clozapine & Clozapine dose

- Clozapine is an antipsychotic medicine. It is a dopamine and serotonin antagonist in CNS. It also antagonizes adrenergic, cholinergic, and histaminergic neurotransmission.

- It is available as 25 mg, 50 mg,100 mg, and 200 mg tablets.

- Clozapine is used in the management of severely and chronically mentally ill schizophrenic patients who have not responded to or cannot tolerate standard antipsychotic drug treatment.

- Learn more about Clozapine ( Clozaril ) mechanism of action, uses, dosage, side effects, and precautions in this video...

- MORE "DRUG IN BRIEF" VIDEOS HERE:
https://www.youtube.com/watch?v=BM5dg5f2daE&t=2s&list=PLL3y4VLBMQfgmQqcppCvUdJvlsoQVlCvI&index=2

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Affiliate Disclaimer: This video and description contains affiliate links, which means that if you click on one of the product links, I'll receive a small commission. This is at no extra cost to you and in many cases include exclusive discounts where applicable. This helps support the channel and allows me to continue to make free videos like this. Thank you for the support!

Clozapine is the single most effective antipsychotic available, and it works in treatment resistant schizophrenia where no other medication is proven to be effective. This video will tell you everything you need to know about this important medication.

Time Stamps:
Topic Intro: 00:00 to 00:32
Old Vs New Medications: 00:33 to 01:20
Efficacy of Clozapine 01:21 to 03:10
Side Effects: 03:11 to 06:39
Mechanism of Action: 06:40 to 9:28
Important steps before starting the medication: 09:29 to 12:28
Dosing: 12:29 to 14:23

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Disclaimer: This is not medical advice, and the information is provided for educational purposes only. Please consult your doctor for any specific medical questions.

All content is created for informational purposes only. The Content is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified health provider. If you think you have a medical emergency, call your doctor, go to the emergency department, or call 911. We do not endorse any specific treatment, tests, or procedures. Reliance on this information is solely at your own risk.

In this video, we uncover the long-term and often irreversible effects of antipsychotic drugs, including brain volume loss, tardive dyskinesia, and cognitive decline.

Most doctors don't discuss these risks in detail, and patients are left unaware of the potential damage caused by these medications.

We’ll explore the evidence from both animal and human studies, explain how these medications affect your brain, and discuss what you can do to mitigate the risks.

If you or a loved one is on antipsychotics, this information is essential to understand the potential long-term consequences.

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🔗 LINKS MENTIONED
- Dorph-Petersen KA, Pierri JN, Perel JM, et al. (2005). The influence of chronic exposure to antipsychotic medications on brain size before and after tissue fixation: A comparison of haloperidol and olanzapine in macaque monkeys. Neuropsychopharmacology, 30, 1649–1661.**
- Fusar-Poli P, Smieskova R, Kempton MJ, Ho BC, Andreasen NC, Borgwardt S. Progressive brain changes in schizophrenia related to antipsychotic treatment? A meta-analysis of longitudinal MRI studies. Neurosci Biobehav Rev. 2013 Sep;37(8):1680-91. doi: 10.1016/j.neubiorev.2013.06.001. Epub 2013 Jun 14. PMID: 23769814; PMCID: PMC3964856.
- Wu JQ, Chen DC, Xiu MH, Tan YL, Yang FD, Kosten TR, Zhang XY. Tardive dyskinesia is associated with greater cognitive impairment in schizophrenia. Prog Neuropsychopharmacol Biol Psychiatry. 2013 Oct 1;46:71-7. doi: 10.1016/j.pnpbp.2013.06.013. Epub 2013 Jul 1. PMID: 23827756.
- https://www.psychiatrictimes.c....om/view/tardive-dysk
- Moncrieff J, Leo J. A systematic review of the effects of antipsychotic drugs on brain volume. Psychol Med. 2010 Sep;40(9):1409-22. doi: 10.1017/S0033291709992297. Epub 2010 Jan 20. PMID: 20085668.

Timestamps:
05:05 Brain Shrinkage and Its Implications
10:04 Movement Disorders: Tardive Dyskinesia Explained
15:11 Cognitive Decline and Long-Term Effects
16:33 Preventative Measures and Alternatives

‼️ DISCLAIMER: All the information on this channel is for educational and/or entertainment purposes and not intended to be specific/personal medical advice from me to you. Watching the videos, or getting answers to comments/question, does not establish a doctor-patient relationship. If you have your own doctor, these videos can maybe help you prepare for your discussion with him. We do our best to spread awareness with these videos, but for legal reasons we can’t answer health questions in the comments. If you leave questions, we’ll make videos about common questions in the future! If we catch incorrect health information, hate speech, illegal solicitation of drugs in the comments, we will remove them.

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► Britain is facing a drugs crisis, as many people rely on highly addictive prescription drugs.

One in four adults in England take sleeping tablets, anti-depressants or painkillers for far longer than they should - and the struggle to get off them can seem impossible.

Health chiefs say that although GPs need to stop handing them out, sometimes they are left with little choice.

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What Are The Side Effects Of Codeine? In this informative video, we will discuss the important aspects of codeine and its potential side effects. Codeine is a medication commonly prescribed for managing pain, but it is essential to be aware of the various reactions it may cause. We will cover common side effects that many individuals may encounter, as well as more serious concerns that could arise with use. Understanding these effects can help you make informed decisions about pain management.

We will also touch on how genetic factors can influence the way codeine is metabolized in the body, which can impact both its effectiveness and the likelihood of experiencing side effects. It is vital to have this knowledge when discussing treatment options with healthcare providers.

Join us as we navigate the complexities of codeine use and its implications for pain management. Whether you are considering codeine for your pain or are simply seeking to understand more about this medication, this video will provide you with essential information. Remember to consult with a healthcare professional before making any changes to your medication regimen.

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About Us: Welcome to Pain Medicine Network, your trusted source for comprehensive information on pain management and treatment options. Our channel is dedicated to exploring the latest advancements in pain medicine, offering insights into innovative therapies, research breakthroughs, and expert interviews.
Please note that our content is purely informational and should not be considered medical advice. Always consult a healthcare professional for personalized guidance and do your own due diligence when it comes to your health and treatment options. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

New research shows many Australians are unaware that taking strong opioid medicatoin for more than a few weeks can actually make their pain worse.

Experts say people are often put on opioid drugs after surgery and find it very difficult to get off them.

Sophie Scott reports.

Read more here: https://www.abc.net.au/news/20....20-06-17/long-term-u

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Promethazine DM is a combination of two medications: an antihistamine and a cough suppressant. It can help relieve cough, runny nose, and sneezing caused by allergies or the common cold.

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MEDICAL ADVICE DISCLAIMER: All content in this video and description including: infor­ma­tion, opinions, con­tent, ref­er­ences and links are for infor­ma­tional pur­poses only. The Author does not pro­vide any med­ical advice on the Site. Access­ing, viewing, read­ing or oth­er­wise using this content does NOT cre­ate a physician-patient rela­tion­ship between you and it’s author. Pro­vid­ing per­sonal or med­ical infor­ma­tion to the Principal author does not cre­ate a physician-patient rela­tion­ship between you and the Principal author or authors. Noth­ing con­tained in this video or it’s description is intended to estab­lish a physician-patient rela­tion­ship, to replace the ser­vices of a trained physi­cian or health care pro­fes­sional, or oth­er­wise to be a sub­sti­tute for pro­fes­sional med­ical advice, diag­no­sis, or treatment. You should con­sult a licensed physi­cian or appropriately-credentialed health care worker in your com­mu­nity in all mat­ters relat­ing to your health.

😷 Do you want a consultation with Dr Chung?
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Email to get details: [email protected]

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DISCLAIMER: This video is purely educational and does not constitute medical advice. The content of this video is my personal opinion and not that of my employer(s). Use of this information is at your own risk. Albert Chung, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness, or death.

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❤️ I wanted to provide a place where you can easily gather supplies that will help you to better deal and heal your problem. I really appreciate you clicking on the links. Your support will help to grow this channel!

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☎️ Dr. Albert Chung’s office info:
Phone: 714-988-8690
Fax: 714-988-2235
Email: [email protected]
Website: https://www.CRSurgeryOC.com

✅ Please read my reviews on Google.com and Yelp.com!

📸 Visit me on Social Media:
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DISCLAIMER: This video is purely educational and does not constitute medical advice. The content of this video is my personal opinion and not that of my employer(s). Use of this information is at your own risk. Albert Chung, M.D. will not assume any liability for any direct or indirect losses or damages that may result from the use of the information contained in this video including but not limited to economic loss, injury, illness, or death.

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In this video, we discuss the "Best Colace Clear 50 MG," a reliable solution for promoting digestive health and regularity. Learn about how this stool softener works, its benefits, and who can benefit from using it. We’ll provide insights on the "Best Colace Clear 50 MG," including dosage recommendations and tips for integrating it into your routine for optimal results!

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​@chubbyemu video about Fiber Supplement: https://www.youtube.com/watch?v=1MggKIfEld4
@HemeReview Audio-only episode A Grandma Collapsed From Abdominal Pain. This Is What Happened To Her Colon: https://anchor.fm/chubbyemu/ep....isodes/A-Grandma-Col

Psyllium husk fiber supplement can be part of a healthy diet, but it must be taken correctly. It has been shown to lower cholesterol levels to an extent, but is best in combination with a proper diet. Always take care to mix psyllium husk with more than enough water. It can become thick and cause problems if it isn't.

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References:

Potential Benefits of Dietary Fibre Intervention in Inflammatory Bowel Disease https://www.ncbi.nlm.nih.gov/p....mc/articles/PMC49264

Effects of psyllium on glucose and serum lipid responses in men with type 2 diabetes and hypercholesterolemia https://academic.oup.com/ajcn/....article/70/4/466/472

Anaphylaxis following psyllium ingestion https://pubmed.ncbi.nlm.nih.gov/6736485/

Long-term cholesterol-lowering effects of psyllium as an adjunct to diet therapy in the treatment of hypercholesterolemia https://academic.oup.com/ajcn/....article/71/6/1433/47

what is Metamucil ?,
what is Colace?,
what are the Difference Between Metamucil and Colace?,
#medicalknowledgeonline,

Content Disclaimer
"This video provides educational content for informational purposes only and is not a substitute for professional medical advice, diagnosis, or treatment. Always consult your healthcare provider with any questions regarding a medical condition or treatment. We do not endorse any specific treatments, medications, or products discussed on this channel."
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TOPICS
1. ANATOMY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1

2. PHYSIOLOGY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
3. DISEASES – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
4. PUBLIC HEALTH- Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
5. Rx – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
6. LABORATORY TEST – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
7. MEDICAL IMAGING – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
8. SURGICAL AND MEDICAL PROCEDURES – topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
9. MICROBIOLOGY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
10. BIOCHEMISTRY – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
11. NUTRITION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
12. HEALTH TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
13. MEDICAL & SURGICAL – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
14. PAEDIATRICS / CHILD HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
15. MENTAL HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
16. MATERNAL HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
17. COMMUNITY HEALTH – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
18. NURSING FOUNDATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
19. BIOSTATISTICS – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
20. PATHOLOGY – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
21. NURSING EDUCATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
22. HOSPITAL MANAGEMENT AND HEALTH CARE ADMINISTRATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
23. NURSING RESEARCH – TOPICS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
24. NURSING FOUNDATION – Topics
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
25. PHARMACOLOGY – TOPICS
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26. PUBLIC HEALTH – Topics
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27. INTERNATIONAL DAYS
https://www.youtube.com/playli....st?list=PLpHbgG-0bk1
#medicalknowledgeonline

This is video explore the key points and information you should know about your medication. For more Information about the medication click on the following link: https://drive.google.com/file/....d/1SQT9BkZdy_4lCFa_k stamp
00:00-00:42 Intro and Medication presentation
00:43 why am I Taking this medication?
00:49 How should I use this medication?
03:22 what If I miss a dose?
03:45 What side effects can occur?
04:08 What should I tell my healthcare provider before taking This medication?
04:47 where Should I store my medication?

Carmen Enoh
Student Pharmacist
PhamD candidate

PHARMACIST Fi shares the fascinating ways a medicine called colchicine works to reduce inflammation for people with gout. (Some colchicine brand names you might recognize include: Colcrys, Mitigare, or Gloperba in U.S.A.; Colgout, Lengout, or Colcine in Australia.)

Please also watch PHARMACIST Fi's 3 main videos on colchicine for gout:

'Part 1' (via the following link) looks at important things for you and your doctor to talk about before starting colchicine, or when already taking colchicine:
https://www.youtube.com/watch?v=N6jCa795bLg

'Part 2' Looks at potential colchicine side effects everyone should know how to recognize and report to a doctor (although thankfully side effects are less common with modern colchicine dose schedules), and serious medicine interactions to avoid: https://youtu.be/deO0BMqNwWM

'Part 3' gives 7 Top Tips to try to avoid colchicine side effects: https://youtu.be/GSZmW8DkdTY

Here is the link to the playlist of PHARMACIST Fi videos about gout, and gout treatment medicines which may or may not be prescribed (depending on a person's other medical conditions, other medicines, and kidney and liver function levels): https://www.youtube.com/playli....st?list=PLwyYRbsDY3j

Here is the link to the PHARMACIST Fi video about CMIs (a 'CMI' is 'Consumer Medicine Information' - which is the Australian name for a Medicine Information document; in the USA this is called a 'Medication Guide', and in the UK it is called a 'Patient Information Leaflet):
https://www.youtube.com/watch?v=79CF6A5ZZ3I

Here is a link to a PHARMACIST Fi video about medicine interactions (this video has general info and is not specific to colchicine), in case it may also be of interest to you:
https://www.youtube.com/watch?v=ckRihqtel-4

We hope this info has been helpful for you!
Please also see the disclaimer at the end of this video.
If you would like to support PHARMACIST Fi to produce more Medicine Safety videos, please consider making a purchase from her Official Store at: https://pharmacist-fi.myshopif....y.com/collections/al , or making a paypal donation to PHARMACIST Fi at https://www.pharmacistfi.com/donate

#shorts

If you’re experiencing uncomfortable side effects while treating gout, let’s chat about alternatives.

As a gout pain expert, I’m here to help you find relief. Join our Got Gout group on Facebook for more tips and support.

Join here - https://www.facebook.com/group....s/gotgout/?ref=share

#colchicine #diarrhea #gout #painmanagement #health #wellness #painfree #arthritis #medicine

PHILADELPHIA -- Low dose colchicine (Colcrys) appears to be as effective as high doses of the drug in reducing the pain of gout with fewer advers side effects, a researcher said here.

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COLCHICINE Tablets For The GOUT Treatment
Colchicine is a medicine which is used in the Gout treatment. In this video, we cover the colchicine gout treatment, colchicine side effects, colchicine for gout, Colchicine mechanism of action and drug interactions. Colchicine 0.6 mg and colchicine 0.5 mg tablets, which are available in the market, are the most popular dosage former of the medication.
Do you suffer from gout or other inflammatory conditions? Colchicine might be the solution you've been looking for. This medication has been used for centuries to treat a variety of conditions, and its benefits are well-known in the medical community.

Colchicine works by reducing inflammation in the body, which can help alleviate pain and discomfort. It is especially effective in treating gout flare-ups, as well as other inflammatory conditions like familial Mediterranean fever.

One of the key benefits of Colchicine is its ability to help prevent future gout attacks. By taking this medication as prescribed, you can reduce the frequency and severity of flare-ups, allowing you to live a more comfortable and active lifestyle.

It's important to note that Colchicine should only be taken as directed by your healthcare provider. Be sure to follow their instructions carefully and inform them of any other medications you are taking.

If you suffer from gout or other inflammatory conditions, talk to your doctor about whether Colchicine could be right for you. It could make a world of difference in managing your symptoms and improving your quality of life.


#colchicine #gout #inflammation #arthritis #health #wellness #painrelief #treatment #medication #naturalremedies #holistichealth #antiinflammatory #chronicpain #pharmacy #medicine #arthritisawareness #healthyhabits #supplements #prevention #doctor


Chapters:

00:00:00 "Gout and Its Impact on Health"

00:01:00 "Introduction to Colchicine"

00:01:32 "Mechanism of Action of
Colchicine"

00:02:29 "Side Effects and Drug Interactions of Colchicine"

00:03:57 "Dosage Forms and Key Points about Colchicine"

00:05:03 "Conclusion"

watch other videos about Pharmacology

Basic Introduction to Pharmacology

https://youtu.be/YuXIutQy0_k

https://youtu.be/WxXcDYG4vZ0k

https://youtu.be/qIaHalXHYBk

Metronidazole Pharmacology
https://youtu.be/H9O2g42DYuY


Please Subscribe to my channel 🔔 www.youtube.com/@ClearPharmaco....logy145?sub_confirma

Contributor: Don Stader, MD

Educational Pearls:

1. Gout is an arthritis caused by the deposition of urate crystals into the joint space
2. Colchicine works by disrupting microtubules and prevents white blood cells from getting into the joint space which stops the inflammatory response
3. Colchicine has a high rate of adverse events, in particular explosive diarrhea
4. The drug also has a very narrow therapeutic index and overdose is nearly universally fatal, with no antidote or effective treatment option available
5. Alternative agents such as steroids, which reduce the inflammatory response to urate crystals, along with NSAIDs may be better options for treatment

References

Angelidis C, Kotsialou Z, Kossyvakis C, et al. Colchicine Pharmacokinetics and Mechanism of Action. Curr Pharm Des. 2018;24(6):659-663. doi:10.2174/1381612824666180123110042

Finkelstein Y, Aks SE, Hutson JR, et al. Colchicine poisoning: the dark side of an ancient drug. Clin Toxicol (Phila). 2010;48(5):407-414. doi:10.3109/15563650.2010.495348

Dalbeth N, Merriman TR, Stamp LK. Gout. Lancet. 2016;388(10055):2039-2052. doi:10.1016/S0140-6736(16)00346-9

Summarized by Jackson Roos, MS4 | Edited by Erik Verzemnieks, MD

The Emergency Medical Minute is excited to announce that we are now offering AMA PRA Category 1 credits™ via online course modules. To access these and for more information, visit our website at https://emergencymedicalminute.org/cme-courses/ and create an account. 

Donate to EMM today: https://www.paypal.com/donate/....?token=CWfNGAw4j2pU0

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Are Colchicine Side Effects Normal For Gout Treatment? In this informative video, we will discuss the side effects associated with colchicine, a medication commonly used for managing gout. Understanding these side effects is essential for anyone considering or currently using colchicine as part of their treatment plan. We will cover the most frequently reported side effects, particularly those related to the gastrointestinal system, and provide tips on how to manage them effectively.

It's important to be aware that while many side effects are mild, some can be serious and may require immediate medical attention. We'll highlight the signs to watch for and the importance of adhering to prescribed dosages. Regular monitoring through blood tests may also be necessary to ensure your safety during treatment.

If you or someone you know is dealing with gout and considering colchicine, this video is a must-watch. We will also provide guidance on how to communicate with healthcare providers about any concerns or side effects experienced during treatment. Remember, managing gout effectively involves understanding both the benefits and potential risks of the medications used.

Join us in this essential discussion, and subscribe to our channel for more helpful information about gout management and treatment options.

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#Gout #Colchicine #GoutTreatment #GoutRelief #MedicationSideEffects #HealthTips #ChronicPain #JointHealth #GastrointestinalHealth #PatientEducation #Healthcare #MedicalAdvice #GoutAwareness #Wellness #HealthyLiving #MedicationManagement

About Us: Welcome to Gout Relief Guide! Our channel is dedicated to helping you understand and manage gout through informative discussions on crucial topics such as gout symptoms and flare-ups, causes of gout, uric acid levels, gout-friendly diets, foods to avoid with gout, gout medications, managing gout pain, chronic gout management, natural remedies for gout, and preventing gout attacks. We aim to provide relatable and practical advice for your gout management journey. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

In this video Doctor O'Donovan explains key facts about a medication called ALLOPURINOL and how it is used to treat a condition called GOUT - where uric acid crystals build up in the joints.

Allopurinol is also know by its trade or brand names: Zyloric, Uricto or Zyloprim.

In the video we cover:

00:00 Introduction
00:43 What is allopurinol (Zyloprim)?
01:06 Who can and can't take allopurinol?
01:49 How to take allopurinol?
03:24 Side effects of allopurinol
05:43 - Advice if pregnant
06:13 - Taking allopurinol with other medications

Key facts from the NHS:

*Allopurinol reduces the amount of uric acid made by your body's cells. *This reduces symptoms such as swollen and painful joints (gout).
*It may take several months before you feel the full benefit of allopurinol.
*During the first few months of treatment, as allopurinol starts to work, you may get more gout attacks. However, your doctor will prescribe non-steroidal anti-inflammatory drugs (NSAIDs) or colchicine to help with this.
*When allopurinol is taken regularly, it can lower the number of gout attacks and help prevent damage to the joints.
*Usually you will start allopurinol after an acute attack of gout has completely settled.

Further information:

https://www.nhs.uk/medicines/allopurinol/

https://bnf.nice.org.uk/drugs/allopurinol/

https://www.mayoclinic.org/dru....gs-supplements/allop

#doctor #gout #medication #pharmacy #health #healthcare #goutrelief #zyloprim

************************************************************************
Connect through:

Website: www.doctorodonovan.com
YouTube: www.youtube.com/doctorodonovan​

**************************************************************************
This video has been designed for EDUCATIONAL purposes ONLY and is NOT intended to promote or advertise any prescription-only medication.

Disclaimer:

The video is intended as an educational resource only. The information within this video or on this channel isn't designed to replace professional input, so if you have any medical issues please consult a medical provider. No professional relationship is being created by watching this video. Dr. O’Donovan cannot give any individual medical advice. All information should be verified for accuracy by the individual user. Dr O’Donovan accepts no responsibility for individual interpretation of data, although it is always accurate to the best of his knowledge at the time of the video being published. Dr. O'Donovan does not endorse or promote any medication discussed in this video. Images are used in accordance with fair use guidelines.

Legal information:

Content provided via YouTube is for general EDUCATIONAL factual purposes ONLY. No pharmaceutical company has been involved in creating any aspect of this video. Educational videos are not produced to provide individualised medical advice and are NOT designed as promotion of any medication. Medical education videos on Doctor O'Donovan are not a substitute for professional professional medical advice, diagnosis or treatment. NEVER ignore professional medical advice because of something you have heard here. ALWAYS consult your doctor regarding any concerns about your condition or treatment.


Reporting issues with medications:

In the UK anyone can report an issue with a medicine, vaccine, medical device, blood product or e-cigarette to the Yellow Card scheme.

The Yellow Card scheme is run by the Medicines and Healthcare products Regulatory Agency (MHRA), which safeguards medical products quality and efficacy in the United Kingdom.

Visit this website to do so: https://yellowcard.mhra.gov.uk

Harold Koplewicz: Your Brain on Ritalin
New videos DAILY: https://bigth.ink/youtube
Join Big Think Edge for exclusive videos: https://bigth.ink/Edge
----------------------------------------------------------------------------------
Koplewicz debunks the myth that Ritalin and Adderall affect those without ADHD differently than those with it. The effect is the same.
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HAROLD KOPLEWICZ:

Dr. Harold Koplewicz is one of the nation’s leading child and adolescent psychiatrists. He is widely recognized as an innovator in the field, a strong advocate for child mental health, and a master clinician. He has also been at the forefront of public education to dispel the myths and stigma surrounding children and adolescents living with psychiatric disorders. Koplewicz has been repeatedly recognized in America’s Top Doctors, Best Doctors in America, and New York Magazine’s “Best Doctors in New York.” In 2006, he was appointed Director of the Nathan S. Kline Institute for Psychiatric Research (NKI), making him the third person to hold that position since the institution’s founding in 1952. He is also the founding president of the Child Mind Institute.
----------------------------------------------------------------------------------
TRANSCRIPT:

Question: Do ADHD drugs affect a “normal” brain differently than a brain with ADHD?

Harold Koplewicz: Well I think that’s a myth. I think there’s a myth out there that if you are a hyper-active, or ADHD kid, Ritalin or Ritalin-like medications are going to work on you differently than they will on the normal population. And that’s what it is. It’s a myth; it’s inaccurate. So for all of us, whenever we would take on of these medicines, your dopamine and norepinephrine is going to be more readily available in your brain. You will be more focused. You will be more attentive, you will also, might be a little more uptight and a little more hyper-vigilant. And when you take any medicine, there’s a cost/benefit ratio. Any time you take a medicine, there’s a potential side effect. So if you don’t have ADHD and you’re going to take this medicine, any psychostimulant, any type of drug like this is going to increase your heart rate, it may elevate your blood pressure, it will decrease your appetite. Those things are side effects that are unnecessary if your dopamine and norepinephrine levels are normal. In the same way that if you take too many aspirin. It will thin your platelets, which might be good, but might be bad. And if you take too much aspirin you can actually get an ulcer.

So this is something that every time you get prescribed a medicine, a doctor is thinking about what the cost/benefit ratio is. A little quick soundbyte..

So, but the important part for us to remember is that when someone with ADHD gets these medicines, they get closer to what a normal, typical brain response is. So that they look less hyper-active, they look more attentive, therefore they’re less impulsive. They are able to do what they’re capable of doing. It doesn’t increase your IQ points, it doesn’t make you smarter, it lets you get to the IQ points that you do have. And therefore, while you’re never as attentive as a typical or normal individual, and you never stop moving around and stay as still as a typical normal, you are more in the normal range that permits you to be more contemplative, insightful, and therefore get in touch with and use your intelligence.

Question: Is there any danger of addiction or long-term chemical changes?

Harold Koplewicz: Well, I think there are other side effects. So, for instance, particularly if you take Dexedrine—which is a more potent version of Ritalin, slightly different chemical structure—there is no doubt that you will also get a slight rise in your mood and you will feel somewhat more euphoric and you will feel more expansive. And therefore, if you start taking that medicine on a regular basis, when you don’t have it you very possibly will feel a crash, or you will feel down. And therefore, that’s the potential side effect that could be quite serious, that you become used to it or become almost addicted to the sensation of feeling good when it’s not necessary to cause you to focus or you don’t need it for extended attention.

Recorded August 18, 2010

Interviewed by Max Miller

In this episode, I discuss a medication known as Ritalin (methylphenidate) and go over 3 things that you should know about it:

1. Some common side effects that you can watch out like like a decrease in appetite or weight loss. You could experience anxiety (8%) or depression (4%) as well.
2. I discuss a Black Box warning concerning dependence with methylphenidate.
3. I go over some situations in which you would not be able to use methylphenidate (contraindications). One example is marked anxiety or agitation as Ritalin my increase these symptoms.

My book is now available! It discusses my experience with Bipolar Disorder.
The Fifth Episode - Inside The Manic Mind.
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For information purposes only!

Let's talk about my concerta experience. We'll discuss the benefits, side effects and dosage of concerta during this video. It's primary use it to treat Attention deficit hyperactivity disorder. In this video, you'll hear hear an honest review on Concerta.

00:00 Intro
00:19 Video Agenda📑
00:55 Transition From Ritalin To Concerta
01:12 Benefits Of Ritalin😇
01:25 My Dosage Of Concerta
01:32 One Dose (Morning) / Day
01:40 Does It Really Work?
01:56 Who Is It Appropriate For?
03:11 Withdrawals
04:13 Concerta Vs Adderall
04:49 Concerta Vs Vyvanse
06:24 Consider This Before Trying Concerta
06:45 Side-Effects
07:30 Does It Initiate Fat Loss?
08:18 Sleep Deprivation and Other Benefits Of Concerta

WELCOME to my youtube channel and during this video, I'm talkIng about concerta, this is 27 milligrams and it can do some miraculous things when it comes to helping you with your focus, concentration and mood. Let this video be your guide, we'll go over my concerta experience. I'll compare it to other alternatives, like: Concerta vs Adderall, concerta vs Vyvanse, Concerta vs Ritalin and I'll go over some of the most common concerns about it, such as Concerta side effects, the Concerta dosage, concerta for a weight loss.

I used concerta for about 3 years on and off and it was my experience was that it is absolutely fantastic, it absolutely works... but the comedowns and the crash were bad enough to make it be an overall negative experience... and for that reason, I'm not a user and I never plan to touch the stuff again. Initially I began taking it after I used Ritalin. Ritalin was used to help me with school. They suggested it because I was having trouble studying... I would read and regress to the beginning of the paragraph repetitively, and it was just damn hard to pay attention. So, I was on Ritalin at a very small dose, and Ritalin was great... it would help you to concentrate for a couple of hours. However, it only lasted 2-3 hours and for this reason, I made the switch to concerta. I started at 18 mg and then went up to 27 milligrams.

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#Concerta #ConcertaADHD #ConcertaSideEffects

Have questions about Cosentyx? You’re not alone and this video gives you the clear, honest answers you’ve been searching for. From surprising side effects to how long it actually takes to work, we’re cutting through the myths and delivering real talk with actual facts on this powerful medication used for psoriasis, psoriatic arthritis & more.

Wondering if Cosentyx is safe long-term? If it causes hair loss or weight changes? Or whether you can still get vaccinated? We break it all down.

If you've Googled “Cosentyx side effects”, “is Cosentyx safe?”, or “how does Cosentyx work?” this is the must-watch guide your doctor didn’t have time to give you.

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#Cosentyx, #CosentyxSideEffects, #CosentyxSafety, #PsoriasisTreatment, #PsoriaticArthritis, #AutoimmuneHelp, #ElderlyHealth, #BiologicMedication, #CosentyxReview, #CosentyxExplained, #CosentyxInjection, #HealthOver50, #ChronicPainRelief, #SafeMedications, #CosentyxLongTerm, #RheumatoidArthritis, #MedicineFacts, #DrugSideEffects, #PatientSupport, and #CosentyxQuestions.

⚠️ DISCLAIMER: This video is for educational purposes only and should not be considered as medical advice. Always consult your healthcare provider for personalized guidance regarding your health or medications.

#medicalknowledgeonline
Generic Name, Brand Names, What is ?,
Vital information, Dosage info,
Before taking this medicine (Precautions ), How to use ,
Miss a dose, Overdose , Stop or Avoid Taking ,
Side Effects, Other Drugs Will Affect,
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Visit https://annenberg.net/Psoriati....c-Arthritis-EULAR-CM for the complete CE/CME activity and to claim credit.

This is module (1 of 5) of the CE/CME activity Psoriatic Arthritis Posters and Abstracts from Amsterdam which covers key posters presented at the Annual European Congress of Rheumatology EULAR 2018 meeting in Amsterdam, June 13-16, 2018.

This module covers:
[THU0325] Secukinumab Demonstrates a Consistent Safety Profile With Up to Five Years Treatment in Patients With Psoriatic Arthritis and Moderate to Severe Plaque Psoriasis: Updated Pooled Safety Analyses

Part 2: https://youtu.be/iS_ul028KUQ

Here are the common questions I get for my injection treatment for my psoriasis. Disclaimer, this is not a cure but it is very close to a cure against psoriasis.

Medicine Name: Secukinumab
Program: Access to Initiation Maintenance
Shots: 10 (2 shots per wk for 5 wks)
Free shots: 5
Duration: Good for approximately 6-7 months
Clinc: A Touch of Hope Cebu Doctor's Medical Arts Bldg
Location: Cebu City Philippines

For other questions please feel free to write them in the comments box below.

Don't forget to like and subscribe to my channel ❤️

Music copy rights: Music: Gather Round, Musician: Fox Morrow, Album: Fox Morrow, Source: https://www.vcg.com/
Camera: iPhone 12

Update 2021: After a long search for a new combination of meds that worked for me, I started taking Tremfya in March of 2021. It started working by May and is still working great, it completely cleared my skin and has kept my joints feeling good! I still have some visible swelling of fingers and toes so they added Otezla to the mix a few weeks ago.

Update 2/7/19: The Cosentyx did not end up working for me. I am now on MTX and Xeljanz.

I have suffered from Psoriatic Arthritis and Psoriasis for almost 20 years. In fact, it was my desire to reduce the inflammation in my body which led me to the Keto lifestyle almost 2 years ago. 5 weeks ago I switched medications from Remicade to Cosentyx. I just finished my 5 weeks of loading doses, so here is my update!

You can read more about my journey with both autoimmune disorders here:
http://ketointhecity.com/blog/2016/1/...



---

Buy my new cookbook, The Easy 5-Ingredient Ketogenic Diet Cookbook on Amazon: http://bit.ly/5IngredientKetoCookbook



For more keto information visit my blog and social platforms!


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Earn CME for related activities: https://hmpeducation.com/

This webcast features a presentations that outlines strategies for PsO treatment selection tailored to disease and patient characteristics.

© 2020 NACCME, an HMP Company

The Update in Treatment of Psoriatic Arthritis webcast will discuss treatment strategies for patients with psoriatic disease.

Faculty: M. Elaine Husni, MD, MPH, Cleveland Clinic

The video was produced by the Cleveland Clinic Foundation Center for Continuing Education and the Dermatology and Plastic Surgery Institute.

Interested in related CME education? Visit http://www.ccfcme.org

5 weeks so far 2 shots per week 300ml and i am feeling AMAZING!

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In this video we will cover everything you need to know about Rosuvastatin, also known as Crestor. We will discuss how and when to use it, we will cover its side effects, dosage and much, much more.

You can find more useful videos on cardiovascular diseases and their treatments here:
https://www.youtube.com/playli....st?list=PLaG3Bo3L0gX

Generic name: Rosuvastatin.
Brand names: Crestor and Ezallor.
Available as tablets and chewable tablets.

How to use it?
- Tablet: just swallow it whole with half a glass of water.
- Chewable tablet: just take the tablets and chew on it until it dissolves. If you want to you can also swallow this tablet whole.
It is best to take this medicine at fixed times. This will make you less likely to forget a dose.

When to use it?
Rosuvastatin is part of a group of drugs called Statins. They inhibit the enzyme HMG-CoA reductase, which normally plays an essential role in the synthesis of cholesterol in the liver. This lowers the circulating LDL, the total cholesterol and increased HDL-cholesterol.
Therefore Rosuvastatin can be used to treat a high cholesterol, familial hypercholesterolemia and it can be used to prevent cardiovascular disease.

What is the correct dosage?
The precise dose will depend on your specific indication of use, the side effect you might experience and the severity of your symptoms. Therefore always use the precise amount and frequency your doctor prescribed you.
- However, when treating adults most doctors will start with an initial dose of 5–10 mg 1×/day, if necessary your doctor might double your dose every 4 weeks up to a maximum dose of 40 mg 1x/day.

What are the side-effects?
- Common: Abdominal pain, Nausea, Constipation, Muscle pain, Diabetes mellitus, Dizziness and Headache.
- Uncommon: Skin Rash, Itching and Urticaria.
- Rare: changes in your blood values, edema, hypersensitivity reaction, muscle tear and inflammation of the pancreas.
- Very rare: it can cause several severe side effects.

Safety:
- First of all it is safe to drive when using Rosuvastatin.
- However, it rarely can cause liver abnormalities which can be increased with consumption of too much alcohol. Therefore it is often advised to not drink or at most 1 glass a day while using Rosuvastatin.
- Furthermore, Rosuvastatin can have interactions with other drugs your are taking. Always discuss this with your prescribing doctor.
- Lastly, do not use Rosuvastatin while pregnant or while breastfeeding, as it can be dangerous.

- Disclaimer: this video and the comments are meant purely informational! This is not medical advice! If you are looking for medical advice always contact your own doctor. -

I want to give special thanks to my sponsors on Patreon:
- Sebastian Houwing: Investor

Literature:
1: Farmacotherapeutisch Kompas. (2022). Rosuvastatine.
2: Apotheek.nl (2022). Rosuvastatine.

* The images in this video are used for educational purposes only. Most of the images and videos in this video come from https://www.canva.com/.

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#Rosuvastatin #Rosuvastatinsideefftects #Crestor #Crestorsideeffects #highcholesterol #cholesterol

Rosuvastatin belongs to a group of medicines called HMG-CoA
reductase inhibitors. It is most common known by its brand name
Crestor .

Cholesterol is taken into the body through food and also made by the liver. It is needed for our body to make hormones, bile and vitamin D. There are two major forms of cholesterol: LDL Low-density lipoprotein also known as
bad cholesterol, and HDL high-density lipoprotein also called
good cholesterol. Too much bad cholesterol can block your blood
vessels and lead to a heart attack or a stroke. On the other hand
the good cholesterol removes the bad cholesterol from the
blood vessels back to to the liver and remove it from the body.
Rosuvastatin works by reducing the amount of bad cholesterol
made by the liver and raises the good cholesterol to reduce the risk
of you getting a heart attack or a stroke.

Before you start Rosuvastatin, you need to tell your doctor
the following:
- if you are allergic to it, or to any ingredients listed on the
packaging.

- if you have any liver disease, kidney disease and breathing
problems.

- if you are pregnant, intend of likely to be pregnant as it may affect
the baby.

- if you are breast feeding or intend to breast feed, Rosuvastatin can
cross breast milk and affect the baby 

- if you get muscle pain, tenderness or weakness from other medicines used to treat high cholesterol or triglycerides
... more in the video

What Strength it comes in? 
Rosuvastatin comes in 10,20 and 40 mg

How to take it?
Depending on your condition and ethnic background, your doctor will decide the most appropriate starting dose for you.
The doses of rosuvastatin are between 10-40 mg taken once a day
at the same time everyday to get the best effect. It doesnt matter if
you take it with or without food. 

Things to be aware of: 
Be careful driving or operating machinery until you know how
this medicine affects you. Rosuvastain generally does not cause
any problems with your ability to drive a car or operate machinery.
However, it may cause dizziness in some people so make are you
know how the medication affects you before you start driving or
operate machinates.
... more in the video

Side Effects: 

• headache
• constipation
• dizziness
• nausea (feeling sick)
• stomach pain
• unusual tiredness

... more in video

These are not the only side effects, more side effects, if you feel unwell, let your doctor or pharmacist know.

More information and side effetcs about Rosuvastatin can be found on
https://www.nps.org.au/assets/....medicines/cb99939e-2
https://www.nhs.uk/conditions/....statins/side-effects


if you are prescribed rosuvastatin, it means the doctor deems that
the benefit of the medications to keep you alive preventing you
from getting a heart attack and stroke outweighs the rare
side effects that very likely might not happen. So, listen to your
doctor. If you experience any of the side effects that I mentioned,
you then inform the doctor immediately and take it from there. 

Now last note, it is great that we live in a world where we have all
these life saving medications available for us, but it is not a good
thing for us to solely rely on these medication and not do any
lifestyle modification. These medication only controls the
condition but does not cure the condition. Things you need to do
besides following the doctor’s instruction carefully to take your
medication daily on time are to
Exercise
Control your diet, reduce fat and salt intake
Quit smoking

These are very important to keep
your body and mind healthy and strong. Work with your local
doctor and pharmacist to achieve these goals.

Link to How to QUIT Smoking FAST : https://youtu.be/mi1v9YsiHLU

Want to see more videos about health and fitness or any other videos? Let me know in the comments below.

Subscribe for new videos ▶ https://www.youtube.com/c/Soonkie
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*All health videos are under Soonkie Pharmacy!

If you want to check out my other more creative life, check out my other playlists on youtube. I hope my creative side will bring joy and laughter to your life. Soonkie, Your online pharmacist with a Dose of FUN! 🙃 lol

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DISCLAIMER:
This video is for general information only and should not be used for the diagnosis or treatment of medical conditions. Pharmacist Soonkie has used all reasonable care in compiling the information but make no warranty as to its accuracy. Always consult a doctor or other healthcare professional for diagnosis and treatment of medical conditions.

Special Thanks to
* Dr. Joel Ten MBBS, FRACGP

Ref:
NPS Medicine Wise
NHS UK

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If you're taking statins or other cholesterol-lowering medication, liver problems or generalized muscle aches are some of the side effects you may experience. Banner Health's Dr. Brian Lyle, an experienced cardiologist at McKee Medical Center, recalls common issues and offers tips to keep an eye on side effects.

Learn more about our doctors at
https://www.bannerhealth.com/physician-directory.